STRINGSTRING
Srot_0014 Srot_0014 Srot_0015 Srot_0015 Srot_0127 Srot_0127 fgd fgd Srot_0141 Srot_0141 Srot_0142 Srot_0142 Srot_0176 Srot_0176 Srot_0191 Srot_0191 Srot_0323 Srot_0323 Srot_0364 Srot_0364 Srot_0365 Srot_0365 Srot_0458 Srot_0458 Srot_0472 Srot_0472 Srot_0542 Srot_0542 Srot_0620 Srot_0620 Srot_0763 Srot_0763 Srot_0770 Srot_0770 Srot_0771 Srot_0771 Srot_0772 Srot_0772 Srot_0824 Srot_0824 Srot_0832 Srot_0832 Srot_1046 Srot_1046 Srot_1047 Srot_1047 Srot_1048 Srot_1048 Srot_1049 Srot_1049 Srot_1120 Srot_1120 Srot_1121 Srot_1121 Srot_1136 Srot_1136 Srot_1315 Srot_1315 Srot_1386 Srot_1386 secD secD secF secF Srot_1455 Srot_1455 Srot_1508 Srot_1508 Srot_1574 Srot_1574 ahpD ahpD Srot_1579 Srot_1579 Srot_1582 Srot_1582 Srot_1829 Srot_1829 Srot_1845 Srot_1845 Srot_1984 Srot_1984 Srot_2097 Srot_2097 Srot_2168 Srot_2168 Srot_2178 Srot_2178 secA secA Srot_2208 Srot_2208 Srot_2247 Srot_2247 secA-2 secA-2 Srot_2429 Srot_2429 Srot_2430 Srot_2430 Srot_2472 Srot_2472 Srot_2598 Srot_2598 secE secE Srot_2769 Srot_2769 Srot_2838 Srot_2838 secY secY Srot_2958 Srot_2958 msrA msrA Srot_2963 Srot_2963 Srot_3014 Srot_3014 Srot_3029 Srot_3029 Srot_3030 Srot_3030 Srot_3031 Srot_3031 Srot_3050 Srot_3050
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Srot_0014KEGG: sen:SACE_7384 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (323 aa)
Srot_0015Thioredoxin; KEGG: mjl:Mjls_5779 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; Belongs to the thioredoxin family. (109 aa)
Srot_0127KEGG: nfa:nfa12230 putative dehydrogenase; TIGRFAM: mycothiol-dependent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (368 aa)
fgdF420-dependent oxidoreductase, G6PDH family; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. (335 aa)
Srot_0141PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mab:MAB_3032 soluble pyridine nucleotide transhydrogenase. (473 aa)
Srot_0142KEGG: rer:RER_59100 hypothetical protein. (252 aa)
Srot_0176KEGG: mjl:Mjls_2657 hypothetical protein. (271 aa)
Srot_0191PFAM: Carboxymuconolactone decarboxylase; KEGG: rer:RER_15470 hypothetical protein. (180 aa)
Srot_0323PFAM: Redoxin domain protein; KEGG: mav:MAV_3729 15 kDa antigen. (170 aa)
Srot_0364KEGG: nfa:nfa21480 putative ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (627 aa)
Srot_0365KEGG: nfa:nfa21470 putative ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (605 aa)
Srot_0458PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: nfa:nfa18570 hypothetical protein. (155 aa)
Srot_0472PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: mab:MAB_0983c zinc-containing alcohol dehydrogenase. (379 aa)
Srot_0542Putative F420-dependent oxidoreductase; KEGG: mab:MAB_0968c luciferase-like hypothetical protein; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (301 aa)
Srot_0620Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (144 aa)
Srot_0763PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: mjl:Mjls_3657 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. (157 aa)
Srot_0770KEGG: sma:SAV_5622 ABC transporter ATP-binding protein; PFAM: ABC transporter related; binding-protein- dependent transport systems inner membrane component; SMART: AAA ATPase. (682 aa)
Srot_0771PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sma:SAV_5620 ABC transporter permease protein. (297 aa)
Srot_0772PFAM: extracellular solute-binding protein family 5; KEGG: sma:SAV_5619 ABC transporter solute-bing protein. (514 aa)
Srot_0824PFAM: superoxide dismutase copper/zinc binding; KEGG: rer:RER_14950 superoxide dismutase. (249 aa)
Srot_0832PFAM: extracellular solute-binding protein family 5; KEGG: nfa:nfa47580 hypothetical protein. (570 aa)
Srot_1046PFAM: extracellular solute-binding protein family 5; KEGG: rha:RHA1_ro05349 ABC oligopeptide transporter, permease component. (560 aa)
Srot_1047TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; KEGG: mbt:JTY_1315 putative oligopeptide-transport ATP-binding protein ABC transporter; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (623 aa)
Srot_1048PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rop:ROP_54510 putative ABC transporter permease protein. (299 aa)
Srot_1049PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rha:RHA1_ro05352 ABC oligopeptide transporter, permease component. (325 aa)
Srot_1120PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rop:ROP_42440 putative ABC transporter permease protein. (309 aa)
Srot_1121PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rha:RHA1_ro04335 ABC peptide transporter, permease component. (303 aa)
Srot_1136KEGG: mab:MAB_3748 putative luciferase-like oxidoreductase; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (345 aa)
Srot_1315PFAM: Siderophore-interacting protein; FAD-binding 9 siderophore-interacting domain protein; KEGG: rer:RER_17020 siderophore-interacting protein. (273 aa)
Srot_1386PFAM: globin; KEGG: mab:MAB_1566c hemoglobin-like protein HbO. (142 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (555 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (367 aa)
Srot_1455PFAM: extracellular solute-binding protein family 5; KEGG: rop:ROP_68770 hypothetical protein. (548 aa)
Srot_1508Alkanesulfonate monooxygenase; KEGG: mmi:MMAR_4200 F420-dependent glucose-6- phosphate dehydrogenase Fgd2. (387 aa)
Srot_1574PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: nfa:nfa37890 putative alkylhydroperoxide reductase. (197 aa)
ahpDAlkylhydroperoxidase, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. (174 aa)
Srot_15795,10-methylenetetrahydromethanopterin reductase; KEGG: kra:Krad_4268 luciferase family protein; PFAM: Luciferase-like, subgroup. (341 aa)
Srot_1582KEGG: msm:MSMEG_6454 hypothetical protein; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (280 aa)
Srot_1829PFAM: Thioredoxin domain; KEGG: rop:ROP_11650 putative thioredoxin. (311 aa)
Srot_1845Hypothetical protein; KEGG: mab:MAB_2246 thiol-specific antioxidant related protein/peroxidoxin BcpB. (218 aa)
Srot_1984KEGG: mab:MAB_4127c dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (466 aa)
Srot_2097KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. (585 aa)
Srot_2168Putative F420-dependent oxidoreductase; KEGG: rha:RHA1_ro02495 5,10- methylenetetrahydromethanopterin reductase; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (342 aa)
Srot_2178Putative F420-dependent oxidoreductase; KEGG: rha:RHA1_ro02495 5,10- methylenetetrahydromethanopterin reductase; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (323 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (921 aa)
Srot_2208KEGG: nfa:nfa55380 hypothetical protein. (291 aa)
Srot_2247PFAM: Carboxymuconolactone decarboxylase; KEGG: rha:RHA1_ro02133 hypothetical protein. (186 aa)
secA-2SecA DEAD domain protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (762 aa)
Srot_2429KEGG: mab:MAB_2261c ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase. (592 aa)
Srot_2430KEGG: mab:MAB_2262c ABC transporter ATP-binding protein; PFAM: ABC transporter related; FAD-binding 9 siderophore-interacting domain protein; Siderophore- interacting protein; ABC transporter transmembrane region; SMART: AAA ATPase. (866 aa)
Srot_2472KEGG: rer:RER_54700 aryl-alcohol dehydrogenase AdhC; TIGRFAM: mycothiol-dependent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (361 aa)
Srot_2598KEGG: mjl:Mjls_0897 putative monooxygenase. (473 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (163 aa)
Srot_2769KEGG: rop:ROP_39410 putative oxidoreductase; TIGRFAM: putative F420-dependent oxidoreductase; PFAM: Luciferase-like, subgroup. (345 aa)
Srot_2838KEGG: mab:MAB_3016c hypothetical protein. (279 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (437 aa)
Srot_2958Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (203 aa)
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (248 aa)
Srot_2963Ferritin Dps family protein; Iron-storage protein. (193 aa)
Srot_3014PFAM: catalytic domain of components of various dehydrogenase complexes; KEGG: mab:MAB_3571c hypothetical protein. (256 aa)
Srot_3029PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mab:MAB_0721 oligopeptide ABC transporter, permease protein. (382 aa)
Srot_3030PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mab:MAB_0720 oligopeptide ABC transporter, permease protein. (352 aa)
Srot_3031PFAM: extracellular solute-binding protein family 5; KEGG: mab:MAB_0719 putative oligopeptide ABC transporter, solute-binding protein. (532 aa)
Srot_3050PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: nfa:nfa5960 putative thioredoxin. (138 aa)
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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