Your Input: | |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (212 aa) |
| | Srot_0185 | TIGRFAM: citrate synthase I; KEGG: rha:RHA1_ro04998 type II citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family. (442 aa) |
| | Srot_0187 | PFAM: monooxygenase FAD-binding; KEGG: gbr:Gbro_3294 monooxygenase FAD-binding protein. (389 aa) |
| | Srot_0273 | TIGRFAM: glutamate decarboxylase; KEGG: rha:RHA1_ro06016 glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; Belongs to the group II decarboxylase family. (449 aa) |
| | Srot_0299 | PFAM: Acyl-CoA dehydrogenase type 2 domain; KEGG: rop:ROP_53450 putative oxidoreductase. (395 aa) |
| | Srot_0301 | TIGRFAM: serine O-acetyltransferase; KEGG: rer:RER_10920 serine acetyltransferase. (194 aa) |
| | Srot_0302 | KEGG: rer:RER_10910 cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa) |
| | Srot_0314 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: nfa:nfa32360 enoyl-CoA hydratase. (349 aa) |
| | Srot_0320 | PFAM: Aldehyde Dehydrogenase; KEGG: rha:RHA1_ro03944 succinic semialdehyde dehydrogenase. (516 aa) |
| | Srot_0384 | KEGG: rop:ROP_35350 glutamate synthase large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein. (1520 aa) |
| | Srot_0385 | KEGG: mul:MUL_5036 glutamate synthase subunit beta; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (482 aa) |
| | Srot_0394 | PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; KEGG: msm:MSMEG_6116 putative OHCU decarboxylase. (171 aa) |
| | Srot_0411 | PFAM: Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; ferredoxin; KEGG: mab:MAB_3918c putative oxidoreductase. (355 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (235 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (515 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (373 aa) |
| | Srot_0467 | Transketolase; KEGG: mab:MAB_2759 transketolase; TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase central region; Belongs to the transketolase family. (714 aa) |
| | Srot_0472 | PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: mab:MAB_0983c zinc-containing alcohol dehydrogenase. (379 aa) |
| | Srot_0479 | KEGG: mva:Mvan_2338 lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | Srot_0519 | PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: mgi:Mflv_4784 carbamoyl-phosphate synthase L chain, ATP-binding. (596 aa) |
| | Srot_0520 | Rhodanese domain protein; KEGG: rer:RER_21240 thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein. (294 aa) |
| | Srot_0533 | KEGG: rop:ROP_08930 glutamine synthetase I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. (446 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (336 aa) |
| | Srot_0537 | PFAM: monooxygenase FAD-binding; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: mab:MAB_3330 putative salicylate hydroxylase. (404 aa) |
| | Srot_0558 | PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: nfa:nfa45590 bifunctional uroporphyrinogen- III synthetase/response regulator domain protein. (402 aa) |
| | Srot_0579 | TIGRFAM: acetyl-CoA acetyltransferase; KEGG: rer:RER_38940 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | Srot_0616 | TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: nfa:nfa35890 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa) |
| | pgk | KEGG: mgi:Mflv_3709 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (408 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (264 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (930 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (451 aa) |
| | Srot_0682 | KEGG: mav:MAV_1509 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein. (471 aa) |
| | Srot_0683 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (358 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (311 aa) |
| | Srot_0716 | PFAM: FAD linked oxidase domain protein; KEGG: rha:RHA1_ro01589 glycolate oxidase FAD-linked subunit. (458 aa) |
| | Srot_0776 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. (457 aa) |
| | Srot_0779 | KEGG: gbr:Gbro_0072 flavin-containing monooxygenase FMO. (505 aa) |
| | Srot_0804 | Hypothetical protein; KEGG: cli:Clim_1716 STE24 endopeptidase. (102 aa) |
| | Srot_0812 | KEGG: rop:ROP_08840 glutamine synthetase I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp. (478 aa) |
| | Srot_0813 | PFAM: glutamine synthetase catalytic region; KEGG: rer:RER_38440 glutamine synthetase III. (731 aa) |
| | Srot_0847 | Glutamate--tRNA ligase; KEGG: nfa:nfa2690 glutamyl-Q tRNA(Asp) synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family. (310 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (308 aa) |
| | Srot_0962 | PFAM: ROK family protein; KEGG: nfa:nfa37580 putative polyphosphate glucokinase. (272 aa) |
| | argD | KEGG: nfa:nfa19390 acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa) |
| | fbiD | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. (236 aa) |
| | Srot_1013 | PFAM: dienelactone hydrolase; KEGG: sen:SACE_5348 putative carboxymethylenebutenolidase precursor (dienelactone hydrolase) (DLH). (248 aa) |
| | Srot_1072 | KEGG: rha:RHA1_ro01105 5,10- methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (336 aa) |
| | Srot_1082 | TIGRFAM: fructose-1,6-bisphosphatase, class II; KEGG: rop:ROP_59270 fructose 1,6-bisphosphatase class II; PFAM: GlpX family protein. (340 aa) |
| | Srot_1118 | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (647 aa) |
| | pfkA | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (344 aa) |
| | Srot_1256 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: mab:MAB_1156c diaminopimelate decarboxylase LysA. (396 aa) |
| | Srot_1302 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1127 aa) |
| | Srot_1311 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: mtb:TBMG_00066 isocitrate dehydrogenase [NADP] icd2; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (745 aa) |
| | Srot_1317 | PFAM: Transketolase domain protein; Transketolase central region; KEGG: rop:ROP_72230 putative pyruvate dehydrogenase E1 component. (772 aa) |
| | Srot_1335 | KEGG: nca:Noca_3205 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (470 aa) |
| | Srot_1367 | TIGRFAM: phosphoserine phosphatase SerB; HAD- superfamily hydrolase, subfamily IB (PSPase-like); KEGG: nfa:nfa42930 putative phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. (420 aa) |
| | cysH | Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (237 aa) |
| | Srot_1378 | KEGG: rer:RER_37460 sulfite reductase; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein. (565 aa) |
| | Srot_1442 | PFAM: Aldose 1-epimerase; KEGG: mul:MUL_0129 hypothetical protein. (305 aa) |
| | Srot_1473 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (935 aa) |
| | Srot_1491 | PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: kra:Krad_2715 alcohol dehydrogenase GroES domain protein. (445 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | Srot_1538 | PFAM: Asp/Glu/hydantoin racemase; KEGG: aau:AAur_3389 hydantoin racemase. (248 aa) |
| | Srot_1540 | TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; KEGG: sco:SCO4972 dehydrogenase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead. (782 aa) |
| | Srot_1541 | PFAM: molybdopterin dehydrogenase FAD-binding; [2Fe- 2S]-binding domain protein; ferredoxin; CO dehydrogenase flavoprotein domain protein; KEGG: sco:SCO4971 dehydrogenase. (481 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (325 aa) |
| | Srot_1587 | KEGG: gbr:Gbro_3315 succinyl-diaminopimelate desuccinylase; TIGRFAM: succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein. (364 aa) |
| | Srot_1615 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (440 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (308 aa) |
| | Srot_1644 | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: rop:ROP_17230 putative uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase. (526 aa) |
| | Srot_1645 | KEGG: gbr:Gbro_1016 porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (332 aa) |
| | Srot_1684 | PFAM: dienelactone hydrolase; KEGG: rha:RHA1_ro01784 dienelactone hydrolase. (327 aa) |
| | hemL | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: mgi:Mflv_0054 glutamate-1-semialdehyde aminotransferase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III. (448 aa) |
| | Srot_1720 | PFAM: DoxX family protein; KEGG: gfo:GFO_3158 membrane protein. (148 aa) |
| | Srot_1726 | PFAM: monooxygenase FAD-binding; KEGG: mva:Mvan_4906 3-(3-hydroxyphenyl)propionate hydroxylase. (532 aa) |
| | Srot_1770 | KEGG: rha:RHA1_ro00862 nitrite reductase [NAD(P)H] large subunit; TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region. (839 aa) |
| | Srot_1771 | Rieske (2Fe-2S) iron-sulfur domain protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; KEGG: rha:RHA1_ro00863 nitrite reductase [NAD(P)H] small subunit. (110 aa) |
| | ureC | TIGRFAM: urease, alpha subunit; KEGG: nfa:nfa25260 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein. (573 aa) |
| | ureB | TIGRFAM: urease, beta subunit; KEGG: rop:ROP_57390 urease beta subunit; PFAM: Urease beta subunit; Belongs to the urease beta subunit family. (119 aa) |
| | ureA | TIGRFAM: urease, gamma subunit; KEGG: mva:Mvan_3084 urease subunit gamma; PFAM: Urease gamma subunit region; Belongs to the urease gamma subunit family. (100 aa) |
| | Srot_1784 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (479 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (726 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (250 aa) |
| | Srot_1835 | PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: kra:Krad_0345 alcohol dehydrogenase GroES domain protein. (350 aa) |
| | Srot_1863 | KEGG: rop:ROP_66530 siroheme synthase CysG; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. (410 aa) |
| | mqo | TIGRFAM: malate/quinone oxidoreductase; KEGG: rer:RER_26040 malate--quinone oxidoreductase; PFAM: Malate:quinone-oxidoreductase. (505 aa) |
| | Srot_1882 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (397 aa) |
| | Srot_1885 | PFAM: NAD-glutamate dehydrogenase; KEGG: nfa:nfa13060 putative NAD-dependent glutamate dehydrogenase. (1580 aa) |
| | Srot_1886 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; KEGG: rha:RHA1_ro06238 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | Srot_1892 | PFAM: Aldehyde Dehydrogenase; KEGG: mva:Mvan_0105 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (472 aa) |
| | Srot_1899 | TIGRFAM: ribose 5-phosphate isomerase; sugar- phosphate isomerase, RpiB/LacA/LacB family; KEGG: nfa:nfa13270 ribose-5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (154 aa) |
| | Srot_1910 | KEGG: rha:RHA1_ro02121 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein. (292 aa) |
| | Srot_1911 | KEGG: mva:Mvan_0801 isocitrate lyase; TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase. (432 aa) |
| | Srot_1937 | PFAM: Aldehyde Dehydrogenase; KEGG: rop:ROP_63370 piperideine-6-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (518 aa) |
| | Srot_1984 | KEGG: mab:MAB_4127c dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (466 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (298 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa) |
| | Srot_2009 | PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; flavodoxin/nitric oxide synthase; FAD- binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: mva:Mvan_3491 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (1393 aa) |
| | Srot_2054 | KEGG: mav:MAV_3847 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein. (531 aa) |
| | Srot_2057 | TIGRFAM: pyruvate kinase; KEGG: rha:RHA1_ro03221 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (473 aa) |
| | Srot_2059 | KEGG: nfa:nfa29950 putative aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (505 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (498 aa) |
| | Srot_2079 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: nca:Noca_0288 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa) |
| | Srot_2097 | KEGG: nfa:nfa16900 dihydrolipoamide acetyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein. (585 aa) |
| | Srot_2154 | KEGG: mab:MAB_3673 succinate dehydrogenase (cytochrome b-556 subunit) SdhC; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit. (126 aa) |
| | Srot_2155 | KEGG: mjl:Mjls_1255 succinate dehydrogenase subunit D. (139 aa) |
| | Srot_2156 | KEGG: rha:RHA1_ro06246 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (585 aa) |
| | Srot_2157 | KEGG: rop:ROP_63040 succinate dehydrogenase iron- sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (267 aa) |
| | Srot_2160 | KEGG: rop:ROP_52500 acetyl-CoA acyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (449 aa) |
| | alc | TIGRFAM: allantoicase; KEGG: rer:RER_47590 allantoicase; PFAM: Allantoicase region; Belongs to the allantoicase family. (345 aa) |
| | Srot_2215 | PFAM: 4-oxalocrotonate tautomerase; KEGG: ach:Achl_0086 4-oxalocrotonate tautomerase. (65 aa) |
| | Srot_2267 | TIGRFAM: glycerate kinase; KEGG: rer:RER_36060 glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (355 aa) |
| | Srot_2307 | KEGG: mab:MAB_1558c allophanate hydrolase; TIGRFAM: allophanate hydrolase; PFAM: Amidase. (552 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (371 aa) |
| | Srot_2370 | Phosphoketolase; KEGG: ami:Amir_1918 phosphoketolase; PFAM: Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase-like; D-xylulose 5-phosphate/D-fructose 6- phosphate phosphoketolase. (814 aa) |
| | Srot_2410 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: cai:Caci_4435 enoyl-CoA hydratase/isomerase. (254 aa) |
| | Srot_2412 | PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: rer:RER_17550 acyl-CoA carboxylase alpha chain. (680 aa) |
| | Srot_2422 | PFAM: monooxygenase FAD-binding; KEGG: scl:sce6695 PheA/TfdB family FAD-binding monooxygenase. (603 aa) |
| | Srot_2423 | PFAM: (2R)-phospho-3-sulfolactate synthase ComA; KEGG: cgb:cg2797 hypothetical protein. (270 aa) |
| | Srot_2440 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ami:Amir_4781 pyridoxal-5'-phosphate- dependent protein beta subunit. (348 aa) |
| | Srot_2443 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: nfa:nfa48630 hypothetical protein. (453 aa) |
| | Srot_2457 | PFAM: Carboxymuconolactone decarboxylase; KEGG: son:SO_0083 carboxymuconolactone decarboxylase family protein. (131 aa) |
| | Srot_2523 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: mab:MAB_0759c putative dehydrogenase (3- hydroxybutyryl-CoA dehydrogenase FadB). (286 aa) |
| | Srot_2536 | PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: svi:Svir_30240 short chain enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. (719 aa) |
| | Srot_2537 | KEGG: gbr:Gbro_4504 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | fumC | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (472 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (436 aa) |
| | Srot_2618 | KEGG: rha:RHA1_ro04291 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (421 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | pgi | KEGG: nfa:nfa49980 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family. (550 aa) |
| | Srot_2637 | PFAM: inositol monophosphatase; KEGG: gbr:Gbro_1322 inositol monophosphatase. (244 aa) |
| | Srot_2654 | TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: mjl:Mjls_2426 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa) |
| | Srot_2670 | LPPG domain protein containing protein; KEGG: rop:ROP_63740 LPPG--FO 2-phopspho-L-lactate transferase; TIGRFAM: LPPG domain protein containing protein; PFAM: protein of unknown function UPF0052 and CofD. (324 aa) |
| | Srot_2671 | KEGG: sen:SACE_6467 F420-0--gamma-glutamyl ligase; TIGRFAM: F420 biosynthesis protein FbiB, C-terminal domain; F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129; nitroreductase. (445 aa) |
| | Srot_2679 | KEGG: mab:MAB_2486c glutamate synthase, large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein. (1823 aa) |
| | Srot_2680 | PFAM: flavodoxin/nitric oxide synthase; FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: mab:MAB_2485c sulfite reductase. (577 aa) |
| | Srot_2684 | Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (545 aa) |
| | Srot_2685 | KEGG: rha:RHA1_ro01266 sulfate adenylyltransferase subunit 2; TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase. (298 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa) |
| | Srot_2723 | PFAM: Amidase; KEGG: svi:Svir_03450 amidase, Asp-tRNAAsn/Glu- tRNAGln amidotransferase A subunit; Belongs to the amidase family. (494 aa) |
| | Srot_2734 | 2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (908 aa) |
| | Srot_2824 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mjl:Mjls_4812 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (242 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (617 aa) |
| | Srot_2876 | PFAM: aminotransferase class I and II; KEGG: ami:Amir_6777 aminotransferase class I and II. (403 aa) |
| | Srot_2884 | TIGRFAM: 2-methylcitrate synthase/citrate synthase II; KEGG: rer:RER_50290 2-methylcitrate synthase/citrate synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family. (382 aa) |
| | Srot_2942 | PFAM: FAD dependent oxidoreductase; KEGG: rer:RER_19350 hypothetical protein. (567 aa) |
| | Srot_2980 | PFAM: carboxyl transferase; KEGG: gbr:Gbro_1840 carboxyl transferase. (540 aa) |
| | Srot_3052 | Thiosulfate sulfurtransferase; PFAM: Rhodanese domain protein; KEGG: gbr:Gbro_3937 thiosulfate sulfurtransferase; SMART: Rhodanese domain protein. (277 aa) |
| | Srot_3065 | KEGG: msm:MSMEG_1294 putative OHCU decarboxylase; TIGRFAM: OHCU decarboxylase; PFAM: Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. (177 aa) |
| | Srot_3066 | Hydroxyisourate hydrolase; KEGG: mmi:MMAR_4947 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (106 aa) |
