STRINGSTRING
Srot_0273 Srot_0273 trpE trpE Srot_0620 Srot_0620 Srot_0770 Srot_0770 Srot_0771 Srot_0771 Srot_0772 Srot_0772 Srot_0871 Srot_0871 Srot_1046 Srot_1046 Srot_1047 Srot_1047 Srot_1048 Srot_1048 Srot_1049 Srot_1049 Srot_1070 Srot_1070 Srot_1112 Srot_1112 Srot_1119 Srot_1119 Srot_1120 Srot_1120 Srot_1121 Srot_1121 Srot_1122 Srot_1122 Srot_1452 Srot_1452 Srot_1455 Srot_1455 Srot_1710 Srot_1710 ffh ffh Srot_2073 Srot_2073 secA secA ftsY ftsY secA-2 secA-2 Srot_2652 Srot_2652 secE secE secY secY Srot_3029 Srot_3029 Srot_3030 Srot_3030 Srot_3031 Srot_3031 Srot_3072 Srot_3072
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Srot_0273TIGRFAM: glutamate decarboxylase; KEGG: rha:RHA1_ro06016 glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; Belongs to the group II decarboxylase family. (449 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (521 aa)
Srot_0620Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (144 aa)
Srot_0770KEGG: sma:SAV_5622 ABC transporter ATP-binding protein; PFAM: ABC transporter related; binding-protein- dependent transport systems inner membrane component; SMART: AAA ATPase. (682 aa)
Srot_0771PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sma:SAV_5620 ABC transporter permease protein. (297 aa)
Srot_0772PFAM: extracellular solute-binding protein family 5; KEGG: sma:SAV_5619 ABC transporter solute-bing protein. (514 aa)
Srot_0871Two component transcriptional regulator, winged helix family; KEGG: rer:RER_37220 turgor pressure transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver. (250 aa)
Srot_1046PFAM: extracellular solute-binding protein family 5; KEGG: rha:RHA1_ro05349 ABC oligopeptide transporter, permease component. (560 aa)
Srot_1047TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; KEGG: mbt:JTY_1315 putative oligopeptide-transport ATP-binding protein ABC transporter; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (623 aa)
Srot_1048PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rop:ROP_54510 putative ABC transporter permease protein. (299 aa)
Srot_1049PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rha:RHA1_ro05352 ABC oligopeptide transporter, permease component. (325 aa)
Srot_1070TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: nfa:nfa17320 putative 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) synthase II; PFAM: DAHP synthetase class II. (465 aa)
Srot_1112KEGG: rer:RER_04800 CRP/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp. (224 aa)
Srot_1119PFAM: extracellular solute-binding protein family 5; KEGG: mpa:MAP0409 hypothetical protein. (563 aa)
Srot_1120PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rop:ROP_42440 putative ABC transporter permease protein. (309 aa)
Srot_1121PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rha:RHA1_ro04335 ABC peptide transporter, permease component. (303 aa)
Srot_1122ABC transporter related protein; KEGG: mbt:JTY_3722 putative dipeptide-transport ATP- binding protein ABC transporter; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily. (548 aa)
Srot_1452KEGG: mjl:Mjls_2314 preprotein translocase subunit YajC; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. (105 aa)
Srot_1455PFAM: extracellular solute-binding protein family 5; KEGG: rop:ROP_68770 hypothetical protein. (548 aa)
Srot_1710PFAM: phosphoesterase; KEGG: cjk:jk0010 putative acid phosphatase. (607 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (516 aa)
Srot_2073PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro06034 long-chain-fatty-acid--CoA ligase. (599 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (921 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (425 aa)
secA-2SecA DEAD domain protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (762 aa)
Srot_2652Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (343 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (163 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (437 aa)
Srot_3029PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mab:MAB_0721 oligopeptide ABC transporter, permease protein. (382 aa)
Srot_3030PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: mab:MAB_0720 oligopeptide ABC transporter, permease protein. (352 aa)
Srot_3031PFAM: extracellular solute-binding protein family 5; KEGG: mab:MAB_0719 putative oligopeptide ABC transporter, solute-binding protein. (532 aa)
Srot_3072KEGG: rop:ROP_34790 putative OxaA family protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein. (320 aa)
Your Current Organism:
Segniliparus rotundus
NCBI taxonomy Id: 640132
Other names: S. rotundus DSM 44985, Segniliparus rotundus ATCC BAA-972, Segniliparus rotundus CIP 108378, Segniliparus rotundus DSM 44985, Segniliparus rotundus JCM 13578, Segniliparus rotundus str. DSM 44985, Segniliparus rotundus strain DSM 44985
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