STRINGSTRING
apt apt surE surE guaA guaA guaB guaB purA purA gmk gmk ADG16745.1 ADG16745.1 ADG16898.1 ADG16898.1 ADG17180.1 ADG17180.1 surE-2 surE-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (188 aa)
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (252 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (527 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (448 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (227 aa)
ADG16745.1PFAM: phosphoribosyltransferase; KEGG: bxe:Bxe_A0515 hypoxanthine-guanine phosphoribosyltransferase. (183 aa)
ADG16898.1TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: bpy:Bphyt_3596 deoxyguanosinetriphosphate triphosphohydrolase-like protein; SMART: metal-dependent phosphohydrolase HD region; Belongs to the dGTPase family. Type 2 subfamily. (424 aa)
ADG17180.1PFAM: glutamine amidotransferase class-I; KEGG: bpy:Bphyt_3928 glutamine amidotransferase. (245 aa)
surE-2Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (259 aa)
Your Current Organism:
Paraburkholderia sp. CCGE1002
NCBI taxonomy Id: 640511
Other names: P. sp. CCGE1002
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