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pckG pckG gpmA gpmA ADG14754.1 ADG14754.1 glk glk ADG14881.1 ADG14881.1 ADG14888.1 ADG14888.1 tpiA tpiA acsA acsA ADG15235.1 ADG15235.1 ADG15284.1 ADG15284.1 ADG15348.1 ADG15348.1 pgi pgi ADG15821.1 ADG15821.1 eno eno ADG15964.1 ADG15964.1 ADG15965.1 ADG15965.1 ADG15966.1 ADG15966.1 ADG16046.1 ADG16046.1 fbp fbp ADG16584.1 ADG16584.1 ADG16585.1 ADG16585.1 pgk pgk ADG16663.1 ADG16663.1 ADG16700.1 ADG16700.1 ADG16712.1 ADG16712.1 fbp-2 fbp-2 ADG17258.1 ADG17258.1 ADG17341.1 ADG17341.1 ADG17536.1 ADG17536.1 ADG17754.1 ADG17754.1 ADG17778.1 ADG17778.1 ADG17903.1 ADG17903.1 ADG17950.1 ADG17950.1 ADG18111.1 ADG18111.1 ADG18129.1 ADG18129.1 ADG18202.1 ADG18202.1 ADG18517.1 ADG18517.1 ADG18964.1 ADG18964.1 ADG19236.1 ADG19236.1 ADG19269.1 ADG19269.1 ADG19305.1 ADG19305.1 ADG19439.1 ADG19439.1 ADG19479.1 ADG19479.1 ADG19491.1 ADG19491.1 ADG19795.1 ADG19795.1 ADG19813.1 ADG19813.1 ADG19814.1 ADG19814.1 pdhA pdhA ADG20003.1 ADG20003.1 ADG20059.1 ADG20059.1 ADG20075.1 ADG20075.1 ADG20510.1 ADG20510.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (618 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
ADG14754.1Phosphomannomutase; KEGG: bxe:Bxe_A3701 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase. (464 aa)
glkTIGRFAM: glucokinase; KEGG: bxe:Bxe_A3454 glucokinase; PFAM: Glucokinase; helix-turn-helix protein RpiR; sugar isomerase (SIS); Belongs to the bacterial glucokinase family. (638 aa)
ADG14881.1KEGG: bac:BamMC406_0134 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (508 aa)
ADG14888.1KEGG: bpy:Bphyt_1095 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (479 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (258 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
ADG15235.1PFAM: Aldehyde Dehydrogenase; KEGG: vap:Vapar_6271 aldehyde dehydrogenase. (474 aa)
ADG15284.1KEGG: bxe:Bxe_A2810 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (476 aa)
ADG15348.1TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; KEGG: bcj:BCAM2368 putative quinoprotein ethanol dehydrogenase precursor; SMART: Pyrrolo-quinoline quinone beta-propeller repeat. (575 aa)
pgiKEGG: bpy:Bphyt_1914 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family. (540 aa)
ADG15821.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (800 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
ADG15964.1KEGG: bpy:Bphyt_2589 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; biotin/lipoyl attachment domain-containing protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (588 aa)
ADG15965.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (560 aa)
ADG15966.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (901 aa)
ADG16046.1PFAM: AMP-dependent synthetase and ligase; KEGG: bpy:Bphyt_2727 AMP-dependent synthetase and ligase. (554 aa)
fbpPFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: bxe:Bxe_A0920 fructose-1,6-bisphosphatase. (338 aa)
ADG16584.1Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
ADG16585.1TIGRFAM: pyruvate kinase; KEGG: bpy:Bphyt_3276 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (478 aa)
pgkKEGG: bpy:Bphyt_3277 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
ADG16663.1KEGG: bpy:Bphyt_3348 phosphoglycerate mutase; manually curated; PFAM: Phosphoglycerate mutase. (224 aa)
ADG16700.1TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: bpy:Bphyt_3390 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
ADG16712.1PFAM: Aldose 1-epimerase; KEGG: bpy:Bphyt_3405 aldose 1-epimerase. (353 aa)
fbp-2PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: bxe:Bxe_B2450 fructose-1,6-bisphosphatase. (367 aa)
ADG17258.1Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (345 aa)
ADG17341.1Gluconate 2-dehydrogenase (acceptor); KEGG: bxe:Bxe_C0083 putative alcohol dehydrogenase cytochrome c subunit; PFAM: cytochrome c class I. (442 aa)
ADG17536.1PFAM: Lactate/malate dehydrogenase; KEGG: geo:Geob_0424 L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (315 aa)
ADG17754.1PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bxe:Bxe_B1754 zinc-containing alcohol dehydrogenase superfamily protein. (350 aa)
ADG17778.1KEGG: bpy:Bphyt_4961 gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I. (434 aa)
ADG17903.1KEGG: bxe:Bxe_B1334 fructose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-I. (339 aa)
ADG17950.1KEGG: bpy:Bphyt_5336 HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase. (204 aa)
ADG18111.1PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: dar:Daro_1348 zinc-containing alcohol dehydrogenase superfamily protein. (369 aa)
ADG18129.1PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: vei:Veis_4413 alcohol dehydrogenase. (205 aa)
ADG18202.1PFAM: AMP-dependent synthetase and ligase; KEGG: bpy:Bphyt_5649 AMP-dependent synthetase and ligase. (563 aa)
ADG18517.1PFAM: Aldehyde Dehydrogenase; KEGG: bph:Bphy_6594 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (504 aa)
ADG18964.1KEGG: bpy:Bphyt_7098 ROK family protein; manually curated; PFAM: ROK family protein. (274 aa)
ADG19236.1Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (364 aa)
ADG19269.1PFAM: Aldehyde Dehydrogenase; KEGG: bxe:Bxe_B2578 putative aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (499 aa)
ADG19305.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (889 aa)
ADG19439.1PTS system, glucose-specific IIBC subunit; KEGG: cvi:CV_0979 protein-N p-phosphohistidine-sugar phosphotransferase; TIGRFAM: PTS system, glucose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site. (596 aa)
ADG19479.1PQQ-dependent enzyme-like protein; KEGG: bxe:Bxe_B2415 putative quinoprotein alcohol dehydrogenase; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone; SMART: Pyrrolo-quinoline quinone beta-propeller repeat. (577 aa)
ADG19491.1KEGG: bph:Bphy_4796 gluconate 2-dehydrogenase (acceptor); PFAM: cytochrome c class I. (453 aa)
ADG19795.1KEGG: bpy:Bphyt_5114 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
ADG19813.1Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; KEGG: rso:RSc1799 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein. (372 aa)
ADG19814.1PFAM: Transketolase central region; Transketolase domain protein; KEGG: bph:Bphy_6076 transketolase central region. (326 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa)
ADG20003.1KEGG: bpy:Bphyt_6316 zinc-binding alcohol dehydrogenase family protein; TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein. (328 aa)
ADG20059.1PFAM: Aldehyde Dehydrogenase; KEGG: bam:Bamb_5214 betaine-aldehyde dehydrogenase. (488 aa)
ADG20075.1PFAM: Aldehyde Dehydrogenase; KEGG: bmj:BMULJ_03357 NAD-dependent aldehyde dehydrogenase. (544 aa)
ADG20510.1PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: bph:Bphy_3758 branched-chain alpha-keto acid dehydrogenase subunit E2. (369 aa)
Your Current Organism:
Paraburkholderia sp. CCGE1002
NCBI taxonomy Id: 640511
Other names: P. sp. CCGE1002
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