STRINGSTRING
ADG14132.1 ADG14132.1 gpmA gpmA glyA glyA ADG14657.1 ADG14657.1 ppc ppc acsA acsA ADG15498.1 ADG15498.1 ADG15657.1 ADG15657.1 ADG15660.1 ADG15660.1 ADG15821.1 ADG15821.1 eno eno ADG16046.1 ADG16046.1 serC serC ADG16305.1 ADG16305.1 ADG16306.1 ADG16306.1 ADG16307.1 ADG16307.1 ADG16308.1 ADG16308.1 fbp fbp ADG16561.1 ADG16561.1 ADG16584.1 ADG16584.1 ADG16663.1 ADG16663.1 ADG17242.1 ADG17242.1 ffsA ffsA ADG17244.1 ADG17244.1 ADG17245.1 ADG17245.1 ADG17247.1 ADG17247.1 ADG17248.1 ADG17248.1 ADG17249.1 ADG17249.1 fbp-2 fbp-2 ADG17258.1 ADG17258.1 ADG17265.1 ADG17265.1 mch mch ADG17270.1 ADG17270.1 ADG17273.1 ADG17273.1 ADG17280.1 ADG17280.1 ADG17281.1 ADG17281.1 ADG17282.1 ADG17282.1 ADG17283.1 ADG17283.1 ADG17859.1 ADG17859.1 glyA-2 glyA-2 ackA ackA ADG17903.1 ADG17903.1 ADG18202.1 ADG18202.1 ADG19085.1 ADG19085.1 mdh mdh ADG19276.1 ADG19276.1 ADG19282.1 ADG19282.1 ADG19283.1 ADG19283.1 ADG19284.1 ADG19284.1 ADG19285.1 ADG19285.1 ADG19316.1 ADG19316.1 ADG19467.1 ADG19467.1 ackA-2 ackA-2 ADG19795.1 ADG19795.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ADG14132.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: bxe:Bxe_A4423 putative 2-hydroxyacid dehydrogenase. (337 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
ADG14657.1PFAM: aminotransferase class V; KEGG: bpy:Bphyt_0791 aminotransferase class V. (407 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (1072 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
ADG15498.1TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: bpy:Bphyt_1855 phosphoserine phosphatase SerB; PFAM: Haloacid dehalogenase domain protein hydrolase. (279 aa)
ADG15657.1TIGRFAM: methylamine dehydrogenase light chain; KEGG: bac:BamMC406_4994 amine dehydrogenase; PFAM: methylamine dehydrogenase light chain domain protein; Belongs to the aromatic amine dehydrogenase light chain family. (179 aa)
ADG15660.1KEGG: bam:Bamb_4472 amine dehydrogenase; PFAM: methylamine dehydrogenase heavy subunit. (382 aa)
ADG15821.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (800 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
ADG16046.1PFAM: AMP-dependent synthetase and ligase; KEGG: bpy:Bphyt_2727 AMP-dependent synthetase and ligase. (554 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa)
ADG16305.1PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: bpy:Bphyt_3021 NAD-dependent formate dehydrogenase, gamma subunit. (161 aa)
ADG16306.1KEGG: bpy:Bphyt_3022 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding. (524 aa)
ADG16307.1KEGG: bpy:Bphyt_3023 formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molydopterin dinucleotide-binding region. (1012 aa)
ADG16308.1KEGG: bxe:Bxe_A0963 formate dehydrogenase delta subunit. (84 aa)
fbpPFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: bxe:Bxe_A0920 fructose-1,6-bisphosphatase. (338 aa)
ADG16561.1S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (284 aa)
ADG16584.1Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
ADG16663.1KEGG: bpy:Bphyt_3348 phosphoglycerate mutase; manually curated; PFAM: Phosphoglycerate mutase. (224 aa)
ADG17242.1TIGRFAM: formylmethanofuran dehydrogenase subunit C; KEGG: bxe:Bxe_B2464 formylmethanofuran dehydrogenase, subunit C; PFAM: glutamate synthase alpha subunit domain protein. (278 aa)
ffsAFormylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family. (323 aa)
ADG17244.1KEGG: bxe:Bxe_B2462 formylmethanofuran dehydrogenase, subunit A; TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3. (574 aa)
ADG17245.1KEGG: bxe:Bxe_B2461 formylmethanofuran dehydrogenase, subunit B. (459 aa)
ADG17247.1PFAM: protein of unknown function DUF201; KEGG: bxe:Bxe_B2459 hypothetical protein. (347 aa)
ADG17248.1H4MPT-linked C1 transfer pathway protein; KEGG: bxe:Bxe_B2458 tetrahydromethanopterin biosynthesis protein, putative hydrolase; TIGRFAM: H4MPT-linked C1 transfer pathway protein; PFAM: Hydantoinase/oxoprolinase. (369 aa)
ADG17249.1KEGG: bxe:Bxe_B2457 tetrahydromethanopterin biosynthesis protein, putative kinase. (196 aa)
fbp-2PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: bxe:Bxe_B2450 fructose-1,6-bisphosphatase. (367 aa)
ADG17258.1Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (345 aa)
ADG17265.1KEGG: bxe:Bxe_B2436 formaldehyde-activating protein; TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae). (169 aa)
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family. (345 aa)
ADG17270.1PFAM: Methylene-tetrahydromethanopterin dehydrogenase; KEGG: bxe:Bxe_B2431 methylene-tetrahydromethanopterin dehydrogenase(NAD+/NADP+) (MtdB). (308 aa)
ADG17273.1KEGG: bxe:Bxe_B2427 methanol dehydrogenase-like protein (XoxF); TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone. (605 aa)
ADG17280.1KEGG: bxe:Bxe_B2418a hypothetical protein. (307 aa)
ADG17281.1SMART: von Willebrand factor type A; KEGG: bxe:Bxe_B2418 putative MxaC-like protein. (328 aa)
ADG17282.1KEGG: bxe:Bxe_B2417 putative MxaK-like protein. (181 aa)
ADG17283.1KEGG: bxe:Bxe_B2416 putative MxaL-like protein. (331 aa)
ADG17859.1KEGG: bxe:Bxe_B1589 glutathione-independent formaldehyde dehydrogenase; TIGRFAM: formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein. (399 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (383 aa)
ADG17903.1KEGG: bxe:Bxe_B1334 fructose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-I. (339 aa)
ADG18202.1PFAM: AMP-dependent synthetase and ligase; KEGG: bpy:Bphyt_5649 AMP-dependent synthetase and ligase. (563 aa)
ADG19085.1PFAM: aminotransferase class V; KEGG: bpy:Bphyt_6959 serine--glyoxylate transaminase. (406 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
ADG19276.1TIGRFAM: dihydroxyacetone kinase, DhaK subunit; dihydroxyacetone kinase, L subunit; KEGG: bpy:Bphyt_6567 dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase; Dak phosphatase. (567 aa)
ADG19282.1PFAM: molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; KEGG: bxe:Bxe_B2554 formate dehydrogenase-O, major subunit. (196 aa)
ADG19283.1KEGG: bxe:Bxe_B2553 formate dehydrogenase alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (809 aa)
ADG19284.1KEGG: bpy:Bphyt_6559 formate dehydrogenase, beta subunit; TIGRFAM: formate dehydrogenase, beta subunit; PFAM: Formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein. (307 aa)
ADG19285.1TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: bxe:Bxe_B2551 formate dehydrogenase gamma subunit. (218 aa)
ADG19316.1D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (386 aa)
ADG19467.1KEGG: reu:Reut_A1202 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase. (311 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (391 aa)
ADG19795.1KEGG: bpy:Bphyt_5114 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
Your Current Organism:
Paraburkholderia sp. CCGE1002
NCBI taxonomy Id: 640511
Other names: P. sp. CCGE1002
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