(40 nodes) Mixed, incl. Small GTPase Rho, and Diaphanous FH3 Domain network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1EEJ2_HELRO	Uncharacterized protein. (1639 aa)
	T1EFC7_HELRO	Uncharacterized protein. (193 aa)
	T1EG87_HELRO	Profilin; Belongs to the profilin family. (140 aa)
	T1EGW3_HELRO	Uncharacterized protein. (153 aa)
	T1EJC4_HELRO	Protein kinase domain-containing protein. (199 aa)
	T1EKE1_HELRO	Uncharacterized protein. (96 aa)
	T1ELY9_HELRO	Uncharacterized protein. (191 aa)
	T1EMF6_HELRO	Uncharacterized protein. (187 aa)
	T1ER92_HELRO	Uncharacterized protein. (572 aa)
	T1EUD0_HELRO	Uncharacterized protein. (191 aa)
	T1EUQ3_HELRO	Uncharacterized protein. (187 aa)
	T1EWE9_HELRO	Anillin domain-containing protein. (994 aa)
	T1F073_HELRO	ANK_REP_REGION domain-containing protein. (387 aa)
	T1F074_HELRO	ANK_REP_REGION domain-containing protein. (319 aa)
	T1F076_HELRO	ANK_REP_REGION domain-containing protein. (173 aa)
	T1F134_HELRO	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	T1F287_HELRO	Uncharacterized protein. (392 aa)
	T1F2E9_HELRO	Uncharacterized protein. (125 aa)
	T1F2W5_HELRO	FH2 domain-containing protein. (1414 aa)
	T1F3L7_HELRO	Uncharacterized protein. (261 aa)
	T1F9D8_HELRO	FH2 domain-containing protein. (795 aa)
	T1FDC5_HELRO	Uncharacterized protein. (223 aa)
	T1FER4_HELRO	Drf_FH3 domain-containing protein. (113 aa)
	T1FFJ7_HELRO	Uncharacterized protein. (552 aa)
	T1FFZ5_HELRO	Uncharacterized protein. (515 aa)
	T1FGI5_HELRO	Uncharacterized protein. (257 aa)
	T1FRA4_HELRO	DEP domain-containing protein. (2012 aa)
	T1FRW8_HELRO	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1925 aa)
	T1FRZ4_HELRO	Uncharacterized protein. (408 aa)
	T1FSG7_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (251 aa)
	T1FT27_HELRO	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1643 aa)
	T1FU14_HELRO	Uncharacterized protein. (1219 aa)
	T1FVP2_HELRO	Uncharacterized protein. (184 aa)
	T1FWL2_HELRO	PH domain-containing protein. (1714 aa)
	T1FXP1_HELRO	Uncharacterized protein. (944 aa)
	T1FZ83_HELRO	Uncharacterized protein. (192 aa)
	T1G204_HELRO	Uncharacterized protein. (167 aa)
	T1G6H1_HELRO	Uncharacterized protein. (801 aa)
	T1G7E3_HELRO	Uncharacterized protein. (1085 aa)
	T1G951_HELRO	PH domain-containing protein. (409 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EEJ2_HELRO	T1EFC7_HELRO	T1EEJ2	T1EFC7	Uncharacterized protein.	Uncharacterized protein.	0.792
T1EEJ2_HELRO	T1EGW3_HELRO	T1EEJ2	T1EGW3	Uncharacterized protein.	Uncharacterized protein.	0.786
T1EEJ2_HELRO	T1EJC4_HELRO	T1EEJ2	T1EJC4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.500
T1EEJ2_HELRO	T1EKE1_HELRO	T1EEJ2	T1EKE1	Uncharacterized protein.	Uncharacterized protein.	0.582
T1EEJ2_HELRO	T1ELY9_HELRO	T1EEJ2	T1ELY9	Uncharacterized protein.	Uncharacterized protein.	0.786
T1EEJ2_HELRO	T1EMF6_HELRO	T1EEJ2	T1EMF6	Uncharacterized protein.	Uncharacterized protein.	0.792
T1EEJ2_HELRO	T1ER92_HELRO	T1EEJ2	T1ER92	Uncharacterized protein.	Uncharacterized protein.	0.582
T1EEJ2_HELRO	T1EUD0_HELRO	T1EEJ2	T1EUD0	Uncharacterized protein.	Uncharacterized protein.	0.786
T1EEJ2_HELRO	T1EUQ3_HELRO	T1EEJ2	T1EUQ3	Uncharacterized protein.	Uncharacterized protein.	0.582
T1EEJ2_HELRO	T1EWE9_HELRO	T1EEJ2	T1EWE9	Uncharacterized protein.	Anillin domain-containing protein.	0.585
T1EEJ2_HELRO	T1F2W5_HELRO	T1EEJ2	T1F2W5	Uncharacterized protein.	FH2 domain-containing protein.	0.611
T1EEJ2_HELRO	T1F9D8_HELRO	T1EEJ2	T1F9D8	Uncharacterized protein.	FH2 domain-containing protein.	0.611
T1EEJ2_HELRO	T1FER4_HELRO	T1EEJ2	T1FER4	Uncharacterized protein.	Drf_FH3 domain-containing protein.	0.479
T1EEJ2_HELRO	T1FFJ7_HELRO	T1EEJ2	T1FFJ7	Uncharacterized protein.	Uncharacterized protein.	0.582
T1EEJ2_HELRO	T1FFZ5_HELRO	T1EEJ2	T1FFZ5	Uncharacterized protein.	Uncharacterized protein.	0.471
T1EEJ2_HELRO	T1FRA4_HELRO	T1EEJ2	T1FRA4	Uncharacterized protein.	DEP domain-containing protein.	0.456
T1EEJ2_HELRO	T1FRW8_HELRO	T1EEJ2	T1FRW8	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.959
T1EEJ2_HELRO	T1FSG7_HELRO	T1EEJ2	T1FSG7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.471
T1EEJ2_HELRO	T1FT27_HELRO	T1EEJ2	T1FT27	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.471
T1EEJ2_HELRO	T1FU14_HELRO	T1EEJ2	T1FU14	Uncharacterized protein.	Uncharacterized protein.	0.479