(11 nodes) Toll-like receptor signaling pathway, and Ion channel regulatory protein UNC-93 network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1EED9_HELRO	Uncharacterized protein. (610 aa)
	T1EGQ6_HELRO	Uncharacterized protein. (433 aa)
	T1EGT3_HELRO	Uncharacterized protein. (427 aa)
	T1EHA2_HELRO	TIR domain-containing protein. (93 aa)
	T1EK40_HELRO	TIR domain-containing protein. (72 aa)
	T1EQN5_HELRO	TIR domain-containing protein; Belongs to the Toll-like receptor family. (684 aa)
	T1EUA2_HELRO	TIR domain-containing protein. (873 aa)
	T1FRM5_HELRO	TIR domain-containing protein. (749 aa)
	T1FST4_HELRO	TIR domain-containing protein; Belongs to the Toll-like receptor family. (673 aa)
	T1G0W0_HELRO	DUF3456 domain-containing protein. (191 aa)
	T1G558_HELRO	Uncharacterized protein. (468 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EED9_HELRO	T1G0W0_HELRO	T1EED9	T1G0W0	Uncharacterized protein.	DUF3456 domain-containing protein.	0.629
T1EGQ6_HELRO	T1EHA2_HELRO	T1EGQ6	T1EHA2	Uncharacterized protein.	TIR domain-containing protein.	0.494
T1EGQ6_HELRO	T1EK40_HELRO	T1EGQ6	T1EK40	Uncharacterized protein.	TIR domain-containing protein.	0.494
T1EGQ6_HELRO	T1EQN5_HELRO	T1EGQ6	T1EQN5	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.494
T1EGQ6_HELRO	T1EUA2_HELRO	T1EGQ6	T1EUA2	Uncharacterized protein.	TIR domain-containing protein.	0.494
T1EGQ6_HELRO	T1FRM5_HELRO	T1EGQ6	T1FRM5	Uncharacterized protein.	TIR domain-containing protein.	0.494
T1EGQ6_HELRO	T1FST4_HELRO	T1EGQ6	T1FST4	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.494
T1EGQ6_HELRO	T1G0W0_HELRO	T1EGQ6	T1G0W0	Uncharacterized protein.	DUF3456 domain-containing protein.	0.483
T1EGT3_HELRO	T1EHA2_HELRO	T1EGT3	T1EHA2	Uncharacterized protein.	TIR domain-containing protein.	0.494
T1EGT3_HELRO	T1EK40_HELRO	T1EGT3	T1EK40	Uncharacterized protein.	TIR domain-containing protein.	0.494
T1EGT3_HELRO	T1EQN5_HELRO	T1EGT3	T1EQN5	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.494
T1EGT3_HELRO	T1EUA2_HELRO	T1EGT3	T1EUA2	Uncharacterized protein.	TIR domain-containing protein.	0.494
T1EGT3_HELRO	T1FRM5_HELRO	T1EGT3	T1FRM5	Uncharacterized protein.	TIR domain-containing protein.	0.494
T1EGT3_HELRO	T1FST4_HELRO	T1EGT3	T1FST4	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.494
T1EGT3_HELRO	T1G0W0_HELRO	T1EGT3	T1G0W0	Uncharacterized protein.	DUF3456 domain-containing protein.	0.483
T1EHA2_HELRO	T1EGQ6_HELRO	T1EHA2	T1EGQ6	TIR domain-containing protein.	Uncharacterized protein.	0.494
T1EHA2_HELRO	T1EGT3_HELRO	T1EHA2	T1EGT3	TIR domain-containing protein.	Uncharacterized protein.	0.494
T1EHA2_HELRO	T1G558_HELRO	T1EHA2	T1G558	TIR domain-containing protein.	Uncharacterized protein.	0.494
T1EK40_HELRO	T1EGQ6_HELRO	T1EK40	T1EGQ6	TIR domain-containing protein.	Uncharacterized protein.	0.494
T1EK40_HELRO	T1EGT3_HELRO	T1EK40	T1EGT3	TIR domain-containing protein.	Uncharacterized protein.	0.494