(50 nodes) Wnt signaling pathway, and Regulation of establishment of planar polarity network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1EDF0_HELRO	Uncharacterized protein. (441 aa)
	T1EFK9_HELRO	Uncharacterized protein. (394 aa)
	T1EFW4_HELRO	Uncharacterized protein. (369 aa)
	T1EG52_HELRO	Uncharacterized protein. (282 aa)
	T1EG76_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (399 aa)
	T1EGE8_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (303 aa)
	T1EGG0_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (49 aa)
	T1EGR1_HELRO	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (500 aa)
	T1EHT6_HELRO	Uncharacterized protein. (303 aa)
	T1EL13_HELRO	PDZ domain-containing protein. (88 aa)
	T1ELM8_HELRO	Uncharacterized protein. (285 aa)
	T1EMJ1_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (319 aa)
	T1ESK3_HELRO	RING-type domain-containing protein. (583 aa)
	T1EYB4_HELRO	CA domain-containing protein. (985 aa)
	T1F226_HELRO	Uncharacterized protein. (2426 aa)
	T1F3D0_HELRO	Uncharacterized protein. (1959 aa)
	T1F3M5_HELRO	Uncharacterized protein. (609 aa)
	T1F6E5_HELRO	Uncharacterized protein. (382 aa)
	T1F941_HELRO	Uncharacterized protein. (1862 aa)
	T1F9D7_HELRO	FH2 domain-containing protein. (177 aa)
	T1FBL1_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (308 aa)
	T1FIP3_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (275 aa)
	T1FM65_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
	T1FMH4_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (302 aa)
	T1FP01_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
	T1FQ35_HELRO	Uncharacterized protein. (992 aa)
	T1FS49_HELRO	Uncharacterized protein. (290 aa)
	T1FSL1_HELRO	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (634 aa)
	T1FSP2_HELRO	Uncharacterized protein. (585 aa)
	T1FT28_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (472 aa)
	T1FUK4_HELRO	RING-type domain-containing protein. (449 aa)
	T1FVX1_HELRO	Uncharacterized protein. (607 aa)
	T1FWQ2_HELRO	FZ domain-containing protein. (584 aa)
	T1FWS3_HELRO	Uncharacterized protein. (614 aa)
	T1FXD5_HELRO	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (610 aa)
	T1FXM4_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (323 aa)
	T1FY80_HELRO	Uncharacterized protein. (411 aa)
	T1G3I8_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (301 aa)
	T1G4C2_HELRO	PDZ domain-containing protein. (91 aa)
	T1G560_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (252 aa)
	T1G5T5_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (88 aa)
	T1G5U5_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (245 aa)
	T1G749_HELRO	FZ domain-containing protein. (278 aa)
	T1G7D5_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (347 aa)
	T1G7T4_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (311 aa)
	T1G7X0_HELRO	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
	T1G7Y9_HELRO	LIM zinc-binding domain-containing protein. (94 aa)
	T1G947_HELRO	Uncharacterized protein. (303 aa)
	T1G984_HELRO	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (513 aa)
	T1G9M0_HELRO	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (519 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EDF0_HELRO	T1EFK9_HELRO	T1EDF0	T1EFK9	Uncharacterized protein.	Uncharacterized protein.	0.970
T1EDF0_HELRO	T1EFW4_HELRO	T1EDF0	T1EFW4	Uncharacterized protein.	Uncharacterized protein.	0.555
T1EDF0_HELRO	T1EG52_HELRO	T1EDF0	T1EG52	Uncharacterized protein.	Uncharacterized protein.	0.445
T1EDF0_HELRO	T1EGR1_HELRO	T1EDF0	T1EGR1	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.555
T1EDF0_HELRO	T1EHT6_HELRO	T1EDF0	T1EHT6	Uncharacterized protein.	Uncharacterized protein.	0.974
T1EDF0_HELRO	T1EL13_HELRO	T1EDF0	T1EL13	Uncharacterized protein.	PDZ domain-containing protein.	0.713
T1EDF0_HELRO	T1ELM8_HELRO	T1EDF0	T1ELM8	Uncharacterized protein.	Uncharacterized protein.	0.445
T1EDF0_HELRO	T1EYB4_HELRO	T1EDF0	T1EYB4	Uncharacterized protein.	CA domain-containing protein.	0.507
T1EDF0_HELRO	T1F226_HELRO	T1EDF0	T1F226	Uncharacterized protein.	Uncharacterized protein.	0.507
T1EDF0_HELRO	T1F3M5_HELRO	T1EDF0	T1F3M5	Uncharacterized protein.	Uncharacterized protein.	0.489
T1EDF0_HELRO	T1F9D7_HELRO	T1EDF0	T1F9D7	Uncharacterized protein.	FH2 domain-containing protein.	0.481
T1EDF0_HELRO	T1FS49_HELRO	T1EDF0	T1FS49	Uncharacterized protein.	Uncharacterized protein.	0.445
T1EDF0_HELRO	T1FSL1_HELRO	T1EDF0	T1FSL1	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.555
T1EDF0_HELRO	T1FSP2_HELRO	T1EDF0	T1FSP2	Uncharacterized protein.	Uncharacterized protein.	0.489
T1EDF0_HELRO	T1FVX1_HELRO	T1EDF0	T1FVX1	Uncharacterized protein.	Uncharacterized protein.	0.489
T1EDF0_HELRO	T1FWQ2_HELRO	T1EDF0	T1FWQ2	Uncharacterized protein.	FZ domain-containing protein.	0.555
T1EDF0_HELRO	T1FWS3_HELRO	T1EDF0	T1FWS3	Uncharacterized protein.	Uncharacterized protein.	0.905
T1EDF0_HELRO	T1FXD5_HELRO	T1EDF0	T1FXD5	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.555
T1EDF0_HELRO	T1G4C2_HELRO	T1EDF0	T1G4C2	Uncharacterized protein.	PDZ domain-containing protein.	0.771
T1EDF0_HELRO	T1G749_HELRO	T1EDF0	T1G749	Uncharacterized protein.	FZ domain-containing protein.	0.555