(26 nodes) Voltage-gated cation channel calcium and sodium network (Helobdella robusta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	T1EEX7_HELRO	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1792 aa)
	T1EGM2_HELRO	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1864 aa)
	T1EGZ0_HELRO	Uncharacterized protein. (302 aa)
	T1EH36_HELRO	Ion_trans domain-containing protein. (226 aa)
	T1EH93_HELRO	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (155 aa)
	T1EHI1_HELRO	Ion_trans domain-containing protein. (77 aa)
	T1EIJ2_HELRO	Ion_trans domain-containing protein. (70 aa)
	T1EIQ6_HELRO	Uncharacterized protein. (62 aa)
	T1EIU9_HELRO	Ion_trans domain-containing protein. (52 aa)
	T1EJ29_HELRO	Ion_trans domain-containing protein. (346 aa)
	T1EJR2_HELRO	Ion_trans domain-containing protein. (110 aa)
	T1EKC2_HELRO	Uncharacterized protein. (1572 aa)
	T1EM08_HELRO	Ion_trans domain-containing protein. (116 aa)
	T1EQF1_HELRO	Ion_trans domain-containing protein. (283 aa)
	T1F3E3_HELRO	Uncharacterized protein. (2301 aa)
	T1FXE0_HELRO	Ion_trans domain-containing protein. (56 aa)
	T1FXF7_HELRO	Ion_trans domain-containing protein. (80 aa)
	T1FXW1_HELRO	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1823 aa)
	T1FYK0_HELRO	Uncharacterized protein. (1581 aa)
	T1G0H5_HELRO	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1722 aa)
	T1G411_HELRO	Ion_trans domain-containing protein. (205 aa)
	T1G432_HELRO	Ion_trans domain-containing protein. (268 aa)
	T1G6L3_HELRO	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (475 aa)
	T1G6L4_HELRO	Ion_trans domain-containing protein. (289 aa)
	T1G7B6_HELRO	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1792 aa)
	T1G7P3_HELRO	Uncharacterized protein. (100 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EEX7_HELRO	T1EGM2_HELRO	T1EEX7	T1EGM2	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.551
T1EEX7_HELRO	T1EGZ0_HELRO	T1EEX7	T1EGZ0	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Uncharacterized protein.	0.547
T1EEX7_HELRO	T1EH36_HELRO	T1EEX7	T1EH36	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.544
T1EEX7_HELRO	T1EH93_HELRO	T1EEX7	T1EH93	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.544
T1EEX7_HELRO	T1EHI1_HELRO	T1EEX7	T1EHI1	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.664
T1EEX7_HELRO	T1EIJ2_HELRO	T1EEX7	T1EIJ2	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.543
T1EEX7_HELRO	T1EIQ6_HELRO	T1EEX7	T1EIQ6	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Uncharacterized protein.	0.540
T1EEX7_HELRO	T1EIU9_HELRO	T1EEX7	T1EIU9	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.544
T1EEX7_HELRO	T1EJ29_HELRO	T1EEX7	T1EJ29	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.547
T1EEX7_HELRO	T1EJR2_HELRO	T1EEX7	T1EJR2	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.682
T1EEX7_HELRO	T1EKC2_HELRO	T1EEX7	T1EKC2	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Uncharacterized protein.	0.684
T1EEX7_HELRO	T1EM08_HELRO	T1EEX7	T1EM08	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.664
T1EEX7_HELRO	T1F3E3_HELRO	T1EEX7	T1F3E3	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Uncharacterized protein.	0.689
T1EEX7_HELRO	T1FXE0_HELRO	T1EEX7	T1FXE0	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.546
T1EEX7_HELRO	T1FXF7_HELRO	T1EEX7	T1FXF7	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.547
T1EEX7_HELRO	T1FXW1_HELRO	T1EEX7	T1FXW1	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.552
T1EEX7_HELRO	T1FYK0_HELRO	T1EEX7	T1FYK0	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Uncharacterized protein.	0.684
T1EEX7_HELRO	T1G0H5_HELRO	T1EEX7	T1G0H5	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.554
T1EEX7_HELRO	T1G411_HELRO	T1EEX7	T1G411	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.682
T1EEX7_HELRO	T1G432_HELRO	T1EEX7	T1G432	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ion_trans domain-containing protein.	0.685