(42 nodes) Mixed, incl. ERAD pathway, and Josephin domain DUBs network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1ECZ9_HELRO	Uncharacterized protein. (682 aa)
	T1EDA7_HELRO	RING-type domain-containing protein. (658 aa)
	T1EDL7_HELRO	Uncharacterized protein. (459 aa)
	T1EE70_HELRO	Uncharacterized protein. (720 aa)
	T1EFY5_HELRO	Uncharacterized protein; Belongs to the AAA ATPase family. (555 aa)
	T1EIU8_HELRO	UBX domain-containing protein. (58 aa)
	T1EQ81_HELRO	SEP domain-containing protein. (223 aa)
	T1EQJ8_HELRO	Uncharacterized protein. (807 aa)
	T1EQM0_HELRO	PRKCSH domain-containing protein. (907 aa)
	T1ER48_HELRO	Uncharacterized protein. (380 aa)
	T1ESA4_HELRO	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (237 aa)
	T1ET36_HELRO	Uncharacterized protein. (131 aa)
	T1EUR6_HELRO	Uncharacterized protein. (227 aa)
	T1EVI6_HELRO	Uncharacterized protein. (382 aa)
	T1EYV2_HELRO	Uncharacterized protein. (194 aa)
	T1F067_HELRO	UAS domain-containing protein. (430 aa)
	T1F5H2_HELRO	UBX domain-containing protein. (307 aa)
	T1F5H3_HELRO	UBX domain-containing protein. (181 aa)
	T1F8T4_HELRO	RING-type domain-containing protein. (132 aa)
	T1FFN9_HELRO	UBX domain-containing protein. (449 aa)
	T1FKH0_HELRO	Uncharacterized protein. (403 aa)
	T1FMC3_HELRO	Uncharacterized protein. (607 aa)
	T1FNF7_HELRO	Uncharacterized protein. (364 aa)
	T1FNS6_HELRO	Uncharacterized protein. (331 aa)
	T1FP37_HELRO	UBA domain-containing protein. (280 aa)
	T1FQ29_HELRO	Uncharacterized protein. (285 aa)
	T1FQT2_HELRO	UBX domain-containing protein. (539 aa)
	T1FQW1_HELRO	Josephin domain-containing protein. (356 aa)
	T1FR03_HELRO	Uncharacterized protein. (689 aa)
	T1FRD2_HELRO	UBX domain-containing protein. (560 aa)
	T1FS09_HELRO	Uncharacterized protein. (1353 aa)
	T1FUE1_HELRO	Uncharacterized protein; Belongs to the AAA ATPase family. (582 aa)
	T1FXD4_HELRO	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (549 aa)
	T1FY33_HELRO	Uncharacterized protein. (775 aa)
	T1FYY2_HELRO	Uncharacterized protein. (795 aa)
	T1FYZ5_HELRO	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (251 aa)
	T1G0J3_HELRO	RING-type domain-containing protein. (102 aa)
	T1G3A1_HELRO	AAA domain-containing protein. (160 aa)
	T1G4L5_HELRO	PAW domain-containing protein. (616 aa)
	T1G5Z1_HELRO	AAA domain-containing protein; Belongs to the AAA ATPase family. (490 aa)
	T1G7Q9_HELRO	Uncharacterized protein. (335 aa)
	T1G9T6_HELRO	Uncharacterized protein; Belongs to the AAA ATPase family. (841 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1ECZ9_HELRO	T1EDA7_HELRO	T1ECZ9	T1EDA7	Uncharacterized protein.	RING-type domain-containing protein.	0.871
T1ECZ9_HELRO	T1EE70_HELRO	T1ECZ9	T1EE70	Uncharacterized protein.	Uncharacterized protein.	0.732
T1ECZ9_HELRO	T1EFY5_HELRO	T1ECZ9	T1EFY5	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.732
T1ECZ9_HELRO	T1EQM0_HELRO	T1ECZ9	T1EQM0	Uncharacterized protein.	PRKCSH domain-containing protein.	0.937
T1ECZ9_HELRO	T1ESA4_HELRO	T1ECZ9	T1ESA4	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.990
T1ECZ9_HELRO	T1F8T4_HELRO	T1ECZ9	T1F8T4	Uncharacterized protein.	RING-type domain-containing protein.	0.598
T1ECZ9_HELRO	T1FKH0_HELRO	T1ECZ9	T1FKH0	Uncharacterized protein.	Uncharacterized protein.	0.937
T1ECZ9_HELRO	T1FMC3_HELRO	T1ECZ9	T1FMC3	Uncharacterized protein.	Uncharacterized protein.	0.458
T1ECZ9_HELRO	T1FQ29_HELRO	T1ECZ9	T1FQ29	Uncharacterized protein.	Uncharacterized protein.	0.448
T1ECZ9_HELRO	T1FS09_HELRO	T1ECZ9	T1FS09	Uncharacterized protein.	Uncharacterized protein.	0.871
T1ECZ9_HELRO	T1FXD4_HELRO	T1ECZ9	T1FXD4	Uncharacterized protein.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.406
T1ECZ9_HELRO	T1FY33_HELRO	T1ECZ9	T1FY33	Uncharacterized protein.	Uncharacterized protein.	0.732
T1ECZ9_HELRO	T1FYZ5_HELRO	T1ECZ9	T1FYZ5	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.946
T1ECZ9_HELRO	T1G0J3_HELRO	T1ECZ9	T1G0J3	Uncharacterized protein.	RING-type domain-containing protein.	0.598
T1ECZ9_HELRO	T1G3A1_HELRO	T1ECZ9	T1G3A1	Uncharacterized protein.	AAA domain-containing protein.	0.732
T1ECZ9_HELRO	T1G9T6_HELRO	T1ECZ9	T1G9T6	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.732
T1EDA7_HELRO	T1ECZ9_HELRO	T1EDA7	T1ECZ9	RING-type domain-containing protein.	Uncharacterized protein.	0.871
T1EDA7_HELRO	T1EE70_HELRO	T1EDA7	T1EE70	RING-type domain-containing protein.	Uncharacterized protein.	0.760
T1EDA7_HELRO	T1EFY5_HELRO	T1EDA7	T1EFY5	RING-type domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.760
T1EDA7_HELRO	T1EIU8_HELRO	T1EDA7	T1EIU8	RING-type domain-containing protein.	UBX domain-containing protein.	0.473