(18 nodes) Insertion of tail-anchored proteins into the endoplasmic reticulum membrane, and Cytochrome b5-like Heme/Steroid binding domain network (Helobdella robusta)

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second shell of interactors

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Your Input:
	T1ED36_HELRO	TPR_REGION domain-containing protein. (145 aa)
	T1EDY5_HELRO	MOSC domain-containing protein. (370 aa)
	T1EKX0_HELRO	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (75 aa)
	T1EL91_HELRO	RING-type domain-containing protein. (70 aa)
	T1EL98_HELRO	RING-type domain-containing protein. (51 aa)
	T1EPB6_HELRO	Uncharacterized protein. (146 aa)
	T1EVE6_HELRO	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (113 aa)
	T1F484_HELRO	GLOBIN domain-containing protein; Belongs to the globin family. (215 aa)
	T1FMN0_HELRO	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (132 aa)
	T1FMZ5_HELRO	Ubiquitin-like domain-containing protein. (181 aa)
	T1FNV7_HELRO	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (340 aa)
	T1FPE0_HELRO	Ubiquitin-like domain-containing protein. (557 aa)
	T1FPE1_HELRO	Uncharacterized protein. (529 aa)
	T1FPN1_HELRO	RING-type domain-containing protein. (392 aa)
	T1FPU1_HELRO	RING-type domain-containing protein. (159 aa)
	T1FUH2_HELRO	RING-type domain-containing protein. (443 aa)
	T1FXX8_HELRO	Uncharacterized protein. (64 aa)
	T1G296_HELRO	Uncharacterized protein. (279 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1ED36_HELRO	T1EKX0_HELRO	T1ED36	T1EKX0	TPR_REGION domain-containing protein.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.491
T1ED36_HELRO	T1EPB6_HELRO	T1ED36	T1EPB6	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.571
T1ED36_HELRO	T1EVE6_HELRO	T1ED36	T1EVE6	TPR_REGION domain-containing protein.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.491
T1ED36_HELRO	T1FMN0_HELRO	T1ED36	T1FMN0	TPR_REGION domain-containing protein.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.491
T1ED36_HELRO	T1FNV7_HELRO	T1ED36	T1FNV7	TPR_REGION domain-containing protein.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.811
T1ED36_HELRO	T1FPE0_HELRO	T1ED36	T1FPE0	TPR_REGION domain-containing protein.	Ubiquitin-like domain-containing protein.	0.505
T1ED36_HELRO	T1FPE1_HELRO	T1ED36	T1FPE1	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.505
T1ED36_HELRO	T1FXX8_HELRO	T1ED36	T1FXX8	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.619
T1ED36_HELRO	T1G296_HELRO	T1ED36	T1G296	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.873
T1EDY5_HELRO	T1EKX0_HELRO	T1EDY5	T1EKX0	MOSC domain-containing protein.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.594
T1EDY5_HELRO	T1EVE6_HELRO	T1EDY5	T1EVE6	MOSC domain-containing protein.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.594
T1EDY5_HELRO	T1FMN0_HELRO	T1EDY5	T1FMN0	MOSC domain-containing protein.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.594
T1EKX0_HELRO	T1ED36_HELRO	T1EKX0	T1ED36	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	TPR_REGION domain-containing protein.	0.491
T1EKX0_HELRO	T1EDY5_HELRO	T1EKX0	T1EDY5	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	MOSC domain-containing protein.	0.594
T1EKX0_HELRO	T1F484_HELRO	T1EKX0	T1F484	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	GLOBIN domain-containing protein; Belongs to the globin family.	0.402
T1EKX0_HELRO	T1FPU1_HELRO	T1EKX0	T1FPU1	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	RING-type domain-containing protein.	0.583
T1EKX0_HELRO	T1FXX8_HELRO	T1EKX0	T1FXX8	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Uncharacterized protein.	0.463
T1EL98_HELRO	T1FPE0_HELRO	T1EL98	T1FPE0	RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.615
T1EL98_HELRO	T1FPE1_HELRO	T1EL98	T1FPE1	RING-type domain-containing protein.	Uncharacterized protein.	0.615
T1EL98_HELRO	T1G296_HELRO	T1EL98	T1G296	RING-type domain-containing protein.	Uncharacterized protein.	0.488