(18 nodes) Tryptophan catabolism, and Tyrosine catabolism network (Helobdella robusta)

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Your Input:
	T1ED92_HELRO	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (492 aa)
	T1EDA9_HELRO	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (472 aa)
	T1EE50_HELRO	Transket_pyr domain-containing protein. (821 aa)
	T1EEF7_HELRO	Fumarylacetoacetase. (418 aa)
	T1EEF9_HELRO	Aminotran_1_2 domain-containing protein. (425 aa)
	T1EP92_HELRO	Abhydrolase_3 domain-containing protein. (315 aa)
	T1ERL7_HELRO	Uncharacterized protein. (379 aa)
	T1F8J7_HELRO	Uncharacterized protein; Belongs to the GST superfamily. (227 aa)
	T1FMR2_HELRO	Uncharacterized protein. (315 aa)
	T1FMU4_HELRO	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (475 aa)
	T1FN07_HELRO	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (345 aa)
	T1FN21_HELRO	Uncharacterized protein. (458 aa)
	T1FNN4_HELRO	4-hydroxyphenylpyruvate dioxygenase. (382 aa)
	T1FP43_HELRO	FAA_hydrolase domain-containing protein. (221 aa)
	T1FPR7_HELRO	Aminotran_1_2 domain-containing protein. (442 aa)
	T1FPR8_HELRO	Aminotran_1_2 domain-containing protein. (451 aa)
	T1FQB2_HELRO	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (495 aa)
	T1FYF4_HELRO	Aminotran_1_2 domain-containing protein. (332 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1ED92_HELRO	T1EDA9_HELRO	T1ED92	T1EDA9	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.562
T1ED92_HELRO	T1EE50_HELRO	T1ED92	T1EE50	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Transket_pyr domain-containing protein.	0.547
T1ED92_HELRO	T1EEF7_HELRO	T1ED92	T1EEF7	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Fumarylacetoacetase.	0.646
T1ED92_HELRO	T1FN07_HELRO	T1ED92	T1FN07	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	0.960
T1ED92_HELRO	T1FNN4_HELRO	T1ED92	T1FNN4	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	4-hydroxyphenylpyruvate dioxygenase.	0.411
T1ED92_HELRO	T1FP43_HELRO	T1ED92	T1FP43	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	FAA_hydrolase domain-containing protein.	0.646
T1EDA9_HELRO	T1ED92_HELRO	T1EDA9	T1ED92	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.562
T1EDA9_HELRO	T1EEF7_HELRO	T1EDA9	T1EEF7	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Fumarylacetoacetase.	0.767
T1EDA9_HELRO	T1EEF9_HELRO	T1EDA9	T1EEF9	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.961
T1EDA9_HELRO	T1EP92_HELRO	T1EDA9	T1EP92	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Abhydrolase_3 domain-containing protein.	0.977
T1EDA9_HELRO	T1ERL7_HELRO	T1EDA9	T1ERL7	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.942
T1EDA9_HELRO	T1FMR2_HELRO	T1EDA9	T1FMR2	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.894
T1EDA9_HELRO	T1FMU4_HELRO	T1EDA9	T1FMU4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.737
T1EDA9_HELRO	T1FN07_HELRO	T1EDA9	T1FN07	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	0.780
T1EDA9_HELRO	T1FN21_HELRO	T1EDA9	T1FN21	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.730
T1EDA9_HELRO	T1FNN4_HELRO	T1EDA9	T1FNN4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	4-hydroxyphenylpyruvate dioxygenase.	0.480
T1EDA9_HELRO	T1FP43_HELRO	T1EDA9	T1FP43	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	FAA_hydrolase domain-containing protein.	0.585
T1EDA9_HELRO	T1FPR7_HELRO	T1EDA9	T1FPR7	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.961
T1EDA9_HELRO	T1FPR8_HELRO	T1EDA9	T1FPR8	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Aminotran_1_2 domain-containing protein.	0.961
T1EDA9_HELRO	T1FQB2_HELRO	T1EDA9	T1FQB2	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.999