(22 nodes) Glycosylphosphatidylinositol (GPI)-anchor biosynthesis network (Helobdella robusta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	T1EEI1_HELRO	PigN domain-containing protein. (940 aa)
	T1EFK5_HELRO	Uncharacterized protein. (624 aa)
	T1EG61_HELRO	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (326 aa)
	T1EGI8_HELRO	Uncharacterized protein. (218 aa)
	T1EHU2_HELRO	Uncharacterized protein. (663 aa)
	T1EMA6_HELRO	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (389 aa)
	T1EP62_HELRO	Uncharacterized protein. (155 aa)
	T1F1V3_HELRO	Uncharacterized protein. (405 aa)
	T1F256_HELRO	Mannosyltransferase. (601 aa)
	T1FFJ6_HELRO	Uncharacterized protein. (367 aa)
	T1FH72_HELRO	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (504 aa)
	T1FPA8_HELRO	Uncharacterized protein. (437 aa)
	T1FQM0_HELRO	Mannosyltransferase. (594 aa)
	T1FRD4_HELRO	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (979 aa)
	T1FTG5_HELRO	Uncharacterized protein. (1215 aa)
	T1FXP8_HELRO	Uncharacterized protein. (410 aa)
	T1FYK6_HELRO	Uncharacterized protein. (147 aa)
	T1FZW3_HELRO	PIG-P domain-containing protein. (94 aa)
	T1G138_HELRO	Uncharacterized protein. (396 aa)
	T1G292_HELRO	Uncharacterized protein. (237 aa)
	T1G382_HELRO	Uncharacterized protein. (283 aa)
	T1G5Y3_HELRO	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (528 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EEI1_HELRO	T1EFK5_HELRO	T1EEI1	T1EFK5	PigN domain-containing protein.	Uncharacterized protein.	0.572
T1EEI1_HELRO	T1EG61_HELRO	T1EEI1	T1EG61	PigN domain-containing protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.721
T1EEI1_HELRO	T1EGI8_HELRO	T1EEI1	T1EGI8	PigN domain-containing protein.	Uncharacterized protein.	0.670
T1EEI1_HELRO	T1EHU2_HELRO	T1EEI1	T1EHU2	PigN domain-containing protein.	Uncharacterized protein.	0.560
T1EEI1_HELRO	T1EMA6_HELRO	T1EEI1	T1EMA6	PigN domain-containing protein.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.	0.654
T1EEI1_HELRO	T1EP62_HELRO	T1EEI1	T1EP62	PigN domain-containing protein.	Uncharacterized protein.	0.672
T1EEI1_HELRO	T1F1V3_HELRO	T1EEI1	T1F1V3	PigN domain-containing protein.	Uncharacterized protein.	0.582
T1EEI1_HELRO	T1F256_HELRO	T1EEI1	T1F256	PigN domain-containing protein.	Mannosyltransferase.	0.622
T1EEI1_HELRO	T1FFJ6_HELRO	T1EEI1	T1FFJ6	PigN domain-containing protein.	Uncharacterized protein.	0.493
T1EEI1_HELRO	T1FQM0_HELRO	T1EEI1	T1FQM0	PigN domain-containing protein.	Mannosyltransferase.	0.965
T1EEI1_HELRO	T1FTG5_HELRO	T1EEI1	T1FTG5	PigN domain-containing protein.	Uncharacterized protein.	0.621
T1EEI1_HELRO	T1FYK6_HELRO	T1EEI1	T1FYK6	PigN domain-containing protein.	Uncharacterized protein.	0.827
T1EEI1_HELRO	T1FZW3_HELRO	T1EEI1	T1FZW3	PigN domain-containing protein.	PIG-P domain-containing protein.	0.579
T1EEI1_HELRO	T1G138_HELRO	T1EEI1	T1G138	PigN domain-containing protein.	Uncharacterized protein.	0.672
T1EEI1_HELRO	T1G382_HELRO	T1EEI1	T1G382	PigN domain-containing protein.	Uncharacterized protein.	0.622
T1EEI1_HELRO	T1G5Y3_HELRO	T1EEI1	T1G5Y3	PigN domain-containing protein.	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.	0.964
T1EFK5_HELRO	T1EEI1_HELRO	T1EFK5	T1EEI1	Uncharacterized protein.	PigN domain-containing protein.	0.572
T1EFK5_HELRO	T1EG61_HELRO	T1EFK5	T1EG61	Uncharacterized protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.569
T1EFK5_HELRO	T1EGI8_HELRO	T1EFK5	T1EGI8	Uncharacterized protein.	Uncharacterized protein.	0.965
T1EFK5_HELRO	T1EHU2_HELRO	T1EFK5	T1EHU2	Uncharacterized protein.	Uncharacterized protein.	0.621