(12 nodes) Protease binding network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1EU02_HELRO	A20-type domain-containing protein. (440 aa)
	T1EY29_HELRO	Uncharacterized protein. (659 aa)
	T1F360_HELRO	Uncharacterized protein. (218 aa)
	T1FKA2_HELRO	Uncharacterized protein. (578 aa)
	T1FMP4_HELRO	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (423 aa)
	T1FPG1_HELRO	NFRKB_winged domain-containing protein. (762 aa)
	T1FTR6_HELRO	Tower domain-containing protein. (3257 aa)
	T1FY30_HELRO	Uncharacterized protein. (261 aa)
	T1FYA2_HELRO	RING-type domain-containing protein. (312 aa)
	T1FYZ5_HELRO	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (251 aa)
	T1G119_HELRO	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (493 aa)
	T1G153_HELRO	Protein YIPF. (196 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1FMP4_HELRO	T1G119_HELRO	T1FMP4	T1G119	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.557
T1FYA2_HELRO	T1FYZ5_HELRO	T1FYA2	T1FYZ5	RING-type domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.781
T1FYZ5_HELRO	T1FYA2_HELRO	T1FYZ5	T1FYA2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	RING-type domain-containing protein.	0.781
T1FYZ5_HELRO	T1G153_HELRO	T1FYZ5	T1G153	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Protein YIPF.	0.861
T1G119_HELRO	T1FMP4_HELRO	T1G119	T1FMP4	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	PHB domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.557
T1G153_HELRO	T1FYZ5_HELRO	T1G153	T1FYZ5	Protein YIPF.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.861