node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
T1EDA9_HELRO | T1EFI8_HELRO | T1EDA9 | T1EFI8 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.631 |
T1EDA9_HELRO | T1EFR0_HELRO | T1EDA9 | T1EFR0 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Nicotinamide-nucleotide adenylyltransferase. | 0.575 |
T1EDA9_HELRO | T1ELP5_HELRO | T1EDA9 | T1ELP5 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.645 |
T1EDA9_HELRO | T1FMR2_HELRO | T1EDA9 | T1FMR2 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Uncharacterized protein. | 0.894 |
T1EDA9_HELRO | T1FQB2_HELRO | T1EDA9 | T1FQB2 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.999 |
T1EDA9_HELRO | T1FT24_HELRO | T1EDA9 | T1FT24 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.607 |
T1EFI8_HELRO | T1EDA9_HELRO | T1EFI8 | T1EDA9 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.631 |
T1EFI8_HELRO | T1EFR0_HELRO | T1EFI8 | T1EFR0 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.994 |
T1EFI8_HELRO | T1ELP5_HELRO | T1EFI8 | T1ELP5 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.977 |
T1EFI8_HELRO | T1FMR2_HELRO | T1EFI8 | T1FMR2 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Uncharacterized protein. | 0.659 |
T1EFI8_HELRO | T1FQB2_HELRO | T1EFI8 | T1FQB2 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.647 |
T1EFI8_HELRO | T1FT24_HELRO | T1EFI8 | T1FT24 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.864 |
T1EFI8_HELRO | T1FZ55_HELRO | T1EFI8 | T1FZ55 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Uncharacterized protein. | 0.556 |
T1EFR0_HELRO | T1EDA9_HELRO | T1EFR0 | T1EDA9 | Nicotinamide-nucleotide adenylyltransferase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.575 |
T1EFR0_HELRO | T1EFI8_HELRO | T1EFR0 | T1EFI8 | Nicotinamide-nucleotide adenylyltransferase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.994 |
T1EFR0_HELRO | T1ELP5_HELRO | T1EFR0 | T1ELP5 | Nicotinamide-nucleotide adenylyltransferase. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.994 |
T1EFR0_HELRO | T1FMR2_HELRO | T1EFR0 | T1FMR2 | Nicotinamide-nucleotide adenylyltransferase. | Uncharacterized protein. | 0.576 |
T1EFR0_HELRO | T1FQB2_HELRO | T1EFR0 | T1FQB2 | Nicotinamide-nucleotide adenylyltransferase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. | 0.566 |
T1EFR0_HELRO | T1FT24_HELRO | T1EFR0 | T1FT24 | Nicotinamide-nucleotide adenylyltransferase. | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. | 0.994 |
T1EFR0_HELRO | T1FZ55_HELRO | T1EFR0 | T1FZ55 | Nicotinamide-nucleotide adenylyltransferase. | Uncharacterized protein. | 0.960 |