(62 nodes) Cytoplasmic side of plasma membrane network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Esyt2a	Extended synaptotagmin-like protein 2a. (333 aa)
	T1EG99_HELRO	WD_REPEATS_REGION domain-containing protein. (368 aa)
	T1EF69_HELRO	Uncharacterized protein. (361 aa)
	T1EF45_HELRO	Protein kinase domain-containing protein. (203 aa)
	T1FP44_HELRO	Protein kinase domain-containing protein. (327 aa)
	T1FP45_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (319 aa)
	T1G1E7_HELRO	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	T1G0A1_HELRO	Protein kinase domain-containing protein. (89 aa)
	T1G039_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (310 aa)
	T1G028_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (252 aa)
	T1FZD7_HELRO	Uncharacterized protein. (254 aa)
	T1FZA6_HELRO	Uncharacterized protein. (286 aa)
	T1FZ51_HELRO	Uncharacterized protein. (338 aa)
	T1FYQ4_HELRO	MATH domain-containing protein. (207 aa)
	T1FY02_HELRO	IMD domain-containing protein. (155 aa)
	T1FVQ3_HELRO	Uncharacterized protein. (745 aa)
	T1FVE1_HELRO	Uncharacterized protein. (619 aa)
	T1FUN3_HELRO	Protein kinase domain-containing protein. (266 aa)
	T1ESD7_HELRO	Uncharacterized protein. (791 aa)
	T1ESD4_HELRO	Uncharacterized protein. (353 aa)
	T1FU45_HELRO	Uncharacterized protein. (354 aa)
	T1FSK1_HELRO	ML domain-containing protein. (226 aa)
	T1FSC6_HELRO	IMD domain-containing protein. (822 aa)
	T1FPS1_HELRO	Tyrosine-protein kinase. (801 aa)
	T1FP72_HELRO	Uncharacterized protein. (358 aa)
	T1EJL7_HELRO	Protein kinase domain-containing protein. (101 aa)
	T1EIB1_HELRO	Focal_AT domain-containing protein. (76 aa)
	T1ESA8_HELRO	TRAF-type domain-containing protein. (248 aa)
	T1ELZ9_HELRO	Uncharacterized protein. (336 aa)
	T1ELM9_HELRO	Uncharacterized protein. (333 aa)
	T1ELM1_HELRO	Uncharacterized protein. (212 aa)
	T1EKN9_HELRO	Uncharacterized protein. (89 aa)
	T1EJQ0_HELRO	IMD domain-containing protein. (113 aa)
	T1F710_HELRO	Uncharacterized protein. (566 aa)
	T1F703_HELRO	Uncharacterized protein. (561 aa)
	T1F5R4_HELRO	Protein kinase domain-containing protein. (220 aa)
	T1F559_HELRO	Uncharacterized protein. (786 aa)
	T1F321_HELRO	Uncharacterized protein. (540 aa)
	T1F258_HELRO	IMD domain-containing protein. (1158 aa)
	T1EXV6_HELRO	Uncharacterized protein. (152 aa)
	T1EXC1_HELRO	FCH domain-containing protein. (152 aa)
	T1G1R3_HELRO	Protein kinase domain-containing protein. (261 aa)
	T1G222_HELRO	WD_REPEATS_REGION domain-containing protein. (340 aa)
	T1G293_HELRO	MATH domain-containing protein. (195 aa)
	T1G3H9_HELRO	Protein kinase domain-containing protein. (250 aa)
	T1G4B0_HELRO	MATH domain-containing protein. (189 aa)
	T1G5H9_HELRO	Protein kinase domain-containing protein. (229 aa)
	T1G5J5_HELRO	Tyrosine-protein kinase. (473 aa)
	T1G827_HELRO	WD_REPEATS_REGION domain-containing protein. (341 aa)
	T1G8D2_HELRO	WD_REPEATS_REGION domain-containing protein. (328 aa)
	T1G955_HELRO	Uncharacterized protein. (354 aa)
	T1G9A9_HELRO	Uncharacterized protein. (365 aa)
	T1F7F2_HELRO	Uncharacterized protein. (609 aa)
	T1F9B4_HELRO	Uncharacterized protein. (334 aa)
	T1FAS6_HELRO	Uncharacterized protein. (652 aa)
	T1EI38_HELRO	Protein kinase domain-containing protein. (257 aa)
	T1FF04_HELRO	PID domain-containing protein. (198 aa)
	T1FFN9_HELRO	UBX domain-containing protein. (449 aa)
	T1FM18_HELRO	Uncharacterized protein. (353 aa)
	Esyt2b	Extended synaptotagmin-like protein 2b. (846 aa)
	T1FNR7_HELRO	Uncharacterized protein. (354 aa)
	T1EGU2_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (372 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Esyt2a	T1FVE1_HELRO	T1FFK6	T1FVE1	Extended synaptotagmin-like protein 2a.	Uncharacterized protein.	0.647
T1EF45_HELRO	T1EIB1_HELRO	T1EF45	T1EIB1	Protein kinase domain-containing protein.	Focal_AT domain-containing protein.	0.521
T1EF45_HELRO	T1EXC1_HELRO	T1EF45	T1EXC1	Protein kinase domain-containing protein.	FCH domain-containing protein.	0.446
T1EF45_HELRO	T1FZD7_HELRO	T1EF45	T1FZD7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.453
T1EF45_HELRO	T1G028_HELRO	T1EF45	T1G028	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.623
T1EF45_HELRO	T1G039_HELRO	T1EF45	T1G039	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.465
T1EF45_HELRO	T1G5H9_HELRO	T1EF45	T1G5H9	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.722
T1EF69_HELRO	T1EG99_HELRO	T1EF69	T1EG99	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.895
T1EF69_HELRO	T1EKN9_HELRO	T1EF69	T1EKN9	Uncharacterized protein.	Uncharacterized protein.	0.536
T1EF69_HELRO	T1ELM9_HELRO	T1EF69	T1ELM9	Uncharacterized protein.	Uncharacterized protein.	0.591
T1EF69_HELRO	T1ELZ9_HELRO	T1EF69	T1ELZ9	Uncharacterized protein.	Uncharacterized protein.	0.590
T1EF69_HELRO	T1ESD4_HELRO	T1EF69	T1ESD4	Uncharacterized protein.	Uncharacterized protein.	0.640
T1EF69_HELRO	T1FM18_HELRO	T1EF69	T1FM18	Uncharacterized protein.	Uncharacterized protein.	0.640
T1EF69_HELRO	T1FNR7_HELRO	T1EF69	T1FNR7	Uncharacterized protein.	Uncharacterized protein.	0.590
T1EF69_HELRO	T1FP72_HELRO	T1EF69	T1FP72	Uncharacterized protein.	Uncharacterized protein.	0.595
T1EF69_HELRO	T1FU45_HELRO	T1EF69	T1FU45	Uncharacterized protein.	Uncharacterized protein.	0.587
T1EF69_HELRO	T1FZ51_HELRO	T1EF69	T1FZ51	Uncharacterized protein.	Uncharacterized protein.	0.592
T1EF69_HELRO	T1FZA6_HELRO	T1EF69	T1FZA6	Uncharacterized protein.	Uncharacterized protein.	0.782
T1EF69_HELRO	T1G1E7_HELRO	T1EF69	T1G1E7	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.589
T1EF69_HELRO	T1G222_HELRO	T1EF69	T1G222	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.895