(55 nodes) Positive regulation of cell death network (Helobdella robusta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1F9F3_HELRO	Uncharacterized protein. (384 aa)
	T1FAW7_HELRO	Uncharacterized protein. (612 aa)
	T1FB67_HELRO	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (544 aa)
	T1FBB9_HELRO	Uncharacterized protein; Belongs to the peptidase C14A family. (330 aa)
	T1FGB2_HELRO	Uncharacterized protein. (195 aa)
	T1FHT7_HELRO	SARAH domain-containing protein. (316 aa)
	T1FJS2_HELRO	Uncharacterized protein. (276 aa)
	T1FM50_HELRO	Inhibitor of growth protein. (246 aa)
	T1FMH3_HELRO	Inhibitor of growth protein. (255 aa)
	T1FNM8_HELRO	DUF1716 domain-containing protein. (603 aa)
	T1FP67_HELRO	PRELI/MSF1 domain-containing protein. (199 aa)
	T1FPL7_HELRO	Uncharacterized protein. (731 aa)
	T1FPQ1_HELRO	Tyrosine-protein phosphatase domain-containing protein. (363 aa)
	T1FQC3_HELRO	Inhibitor of growth protein. (361 aa)
	T1G9J5_HELRO	Uncharacterized protein. (378 aa)
	T1FSJ3_HELRO	Non-specific serine/threonine protein kinase. (756 aa)
	T1G4N5_HELRO	PDZ domain-containing protein. (391 aa)
	T1FT73_HELRO	Uncharacterized protein. (352 aa)
	T1FTH1_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (427 aa)
	T1FUM1_HELRO	Uncharacterized protein. (1967 aa)
	T1FVH0_HELRO	Uncharacterized protein. (1066 aa)
	T1FVM8_HELRO	Uncharacterized protein. (924 aa)
	T1FYG5_HELRO	USP domain-containing protein. (371 aa)
	T1FYH9_HELRO	Semialdhyde_dh domain-containing protein. (232 aa)
	T1FYJ7_HELRO	C2 NT-type domain-containing protein. (176 aa)
	T1FYR1_HELRO	Uncharacterized protein. (367 aa)
	T1FZD7_HELRO	Uncharacterized protein. (254 aa)
	T1G0C8_HELRO	Uncharacterized protein. (583 aa)
	T1G3V4_HELRO	Uncharacterized protein. (197 aa)
	T1EE34_HELRO	IBR domain-containing protein. (218 aa)
	T1EE77_HELRO	P53 domain-containing protein. (344 aa)
	T1EEC8_HELRO	UDENN FLCN/SMCR8-type domain-containing protein. (597 aa)
	T1EEM5_HELRO	Protein kinase domain-containing protein. (537 aa)
	T1EHM6_HELRO	Homeobox domain-containing protein. (70 aa)
	T1EID8_HELRO	Anti_prolifrtn domain-containing protein. (120 aa)
	T1EIX1_HELRO	Homeobox domain-containing protein. (60 aa)
	T1EJ25_HELRO	Uncharacterized protein; Belongs to the protein kinase superfamily. (402 aa)
	T1EKL4_HELRO	Death domain-containing protein. (120 aa)
	T1ELK5_HELRO	Uncharacterized protein. (113 aa)
	T1G482_HELRO	PRA1 family protein. (179 aa)
	T1G4Q0_HELRO	Uncharacterized protein. (1000 aa)
	T1G4Z2_HELRO	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (316 aa)
	T1G8R2_HELRO	Uncharacterized protein. (79 aa)
	T1G979_HELRO	Peptidase_M48 domain-containing protein. (447 aa)
	T1G994_HELRO	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (718 aa)
	T1EPG8_HELRO	Rhodanese domain-containing protein. (154 aa)
	T1ERI1_HELRO	Uncharacterized protein. (308 aa)
	T1ET05_HELRO	ANK_REP_REGION domain-containing protein. (433 aa)
	T1ET06_HELRO	Death domain-containing protein. (1096 aa)
	T1EY39_HELRO	Uncharacterized protein. (200 aa)
	T1EY96_HELRO	PP1c_bdg domain-containing protein. (578 aa)
	T1EZJ4_HELRO	Uncharacterized protein. (383 aa)
	T1F3E5_HELRO	Uncharacterized protein. (3163 aa)
	T1F8M6_HELRO	Homeobox domain-containing protein. (251 aa)
	T1F8Q6_HELRO	KH type-2 domain-containing protein. (242 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EE34_HELRO	T1FYG5_HELRO	T1EE34	T1FYG5	IBR domain-containing protein.	USP domain-containing protein.	0.625
T1EE34_HELRO	T1FYR1_HELRO	T1EE34	T1FYR1	IBR domain-containing protein.	Uncharacterized protein.	0.625
T1EE34_HELRO	T1G9J5_HELRO	T1EE34	T1G9J5	IBR domain-containing protein.	Uncharacterized protein.	0.520
T1EE77_HELRO	T1FM50_HELRO	T1EE77	T1FM50	P53 domain-containing protein.	Inhibitor of growth protein.	0.457
T1EE77_HELRO	T1FMH3_HELRO	T1EE77	T1FMH3	P53 domain-containing protein.	Inhibitor of growth protein.	0.457
T1EE77_HELRO	T1FQC3_HELRO	T1EE77	T1FQC3	P53 domain-containing protein.	Inhibitor of growth protein.	0.457
T1EEM5_HELRO	T1ET05_HELRO	T1EEM5	T1ET05	Protein kinase domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.841
T1EJ25_HELRO	T1EPG8_HELRO	T1EJ25	T1EPG8	Uncharacterized protein; Belongs to the protein kinase superfamily.	Rhodanese domain-containing protein.	0.505
T1EJ25_HELRO	T1FHT7_HELRO	T1EJ25	T1FHT7	Uncharacterized protein; Belongs to the protein kinase superfamily.	SARAH domain-containing protein.	0.961
T1EJ25_HELRO	T1FPQ1_HELRO	T1EJ25	T1FPQ1	Uncharacterized protein; Belongs to the protein kinase superfamily.	Tyrosine-protein phosphatase domain-containing protein.	0.505
T1ELK5_HELRO	T1F8Q6_HELRO	T1ELK5	T1F8Q6	Uncharacterized protein.	KH type-2 domain-containing protein.	0.849
T1EPG8_HELRO	T1EJ25_HELRO	T1EPG8	T1EJ25	Rhodanese domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.505
T1ET05_HELRO	T1EEM5_HELRO	T1ET05	T1EEM5	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.841
T1ET05_HELRO	T1ET06_HELRO	T1ET05	T1ET06	ANK_REP_REGION domain-containing protein.	Death domain-containing protein.	0.899
T1ET05_HELRO	T1FTH1_HELRO	T1ET05	T1FTH1	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.899
T1ET06_HELRO	T1ET05_HELRO	T1ET06	T1ET05	Death domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.899
T1ET06_HELRO	T1FTH1_HELRO	T1ET06	T1FTH1	Death domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.460
T1ET06_HELRO	T1FVM8_HELRO	T1ET06	T1FVM8	Death domain-containing protein.	Uncharacterized protein.	0.918
T1EZJ4_HELRO	T1FM50_HELRO	T1EZJ4	T1FM50	Uncharacterized protein.	Inhibitor of growth protein.	0.457
T1EZJ4_HELRO	T1FMH3_HELRO	T1EZJ4	T1FMH3	Uncharacterized protein.	Inhibitor of growth protein.	0.457