(15 nodes) Steroid dehydrogenase activity network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1G4L2_HELRO	3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (261 aa)
	T1G7C5_HELRO	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (370 aa)
	T1FVS5_HELRO	R3H-assoc domain-containing protein. (643 aa)
	T1FQG8_HELRO	S5A_REDUCTASE domain-containing protein. (183 aa)
	T1FMV1_HELRO	Uncharacterized protein. (339 aa)
	T1FMT8_HELRO	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (349 aa)
	T1EHZ1_HELRO	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (182 aa)
	T1G124_HELRO	Epimerase domain-containing protein. (353 aa)
	T1G9N3_HELRO	Uncharacterized protein. (732 aa)
	T1FMJ1_HELRO	Uncharacterized protein. (323 aa)
	T1FZE5_HELRO	Epimerase domain-containing protein. (358 aa)
	T1FYP3_HELRO	S5A_REDUCTASE domain-containing protein. (190 aa)
	T1FWZ7_HELRO	Uncharacterized protein. (201 aa)
	T1G2M7_HELRO	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
	T1G2J3_HELRO	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (235 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EHZ1_HELRO	T1FMJ1_HELRO	T1EHZ1	T1FMJ1	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein.	0.611
T1EHZ1_HELRO	T1G2M7_HELRO	T1EHZ1	T1G2M7	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.623
T1FMJ1_HELRO	T1EHZ1_HELRO	T1FMJ1	T1EHZ1	Uncharacterized protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.611
T1FMJ1_HELRO	T1FMV1_HELRO	T1FMJ1	T1FMV1	Uncharacterized protein.	Uncharacterized protein.	0.611
T1FMJ1_HELRO	T1G2J3_HELRO	T1FMJ1	T1G2J3	Uncharacterized protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.611
T1FMT8_HELRO	T1FVS5_HELRO	T1FMT8	T1FVS5	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.	R3H-assoc domain-containing protein.	0.962
T1FMV1_HELRO	T1FMJ1_HELRO	T1FMV1	T1FMJ1	Uncharacterized protein.	Uncharacterized protein.	0.611
T1FMV1_HELRO	T1G2M7_HELRO	T1FMV1	T1G2M7	Uncharacterized protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.620
T1FQG8_HELRO	T1FYP3_HELRO	T1FQG8	T1FYP3	S5A_REDUCTASE domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.906
T1FVS5_HELRO	T1FMT8_HELRO	T1FVS5	T1FMT8	R3H-assoc domain-containing protein.	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.	0.962
T1FVS5_HELRO	T1FZE5_HELRO	T1FVS5	T1FZE5	R3H-assoc domain-containing protein.	Epimerase domain-containing protein.	0.899
T1FVS5_HELRO	T1G124_HELRO	T1FVS5	T1G124	R3H-assoc domain-containing protein.	Epimerase domain-containing protein.	0.595
T1FVS5_HELRO	T1G2M7_HELRO	T1FVS5	T1G2M7	R3H-assoc domain-containing protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.555
T1FVS5_HELRO	T1G7C5_HELRO	T1FVS5	T1G7C5	R3H-assoc domain-containing protein.	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.	0.955
T1FWZ7_HELRO	T1G2M7_HELRO	T1FWZ7	T1G2M7	Uncharacterized protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.563
T1FYP3_HELRO	T1FQG8_HELRO	T1FYP3	T1FQG8	S5A_REDUCTASE domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.906
T1FYP3_HELRO	T1G4L2_HELRO	T1FYP3	T1G4L2	S5A_REDUCTASE domain-containing protein.	3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).	0.425
T1FZE5_HELRO	T1FVS5_HELRO	T1FZE5	T1FVS5	Epimerase domain-containing protein.	R3H-assoc domain-containing protein.	0.899
T1G124_HELRO	T1FVS5_HELRO	T1G124	T1FVS5	Epimerase domain-containing protein.	R3H-assoc domain-containing protein.	0.595
T1G2J3_HELRO	T1FMJ1_HELRO	T1G2J3	T1FMJ1	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein.	0.611