(68 nodes) Macroautophagy network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1FNG8_HELRO	Uncharacterized protein. (204 aa)
	T1ED30_HELRO	ATG_C domain-containing protein. (424 aa)
	T1EDE5_HELRO	N_BRCA1_IG domain-containing protein. (309 aa)
	T1EDL7_HELRO	Uncharacterized protein. (459 aa)
	T1EDQ8_HELRO	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (712 aa)
	T1EDV9_HELRO	RING-type domain-containing protein. (818 aa)
	T1EEA0_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (406 aa)
	T1EEJ7_HELRO	Uncharacterized protein. (709 aa)
	T1EFP5_HELRO	Phosphatidylinositol 3-kinase catalytic subunit type 3. (915 aa)
	T1EFT3_HELRO	Uncharacterized protein. (210 aa)
	T1EHB4_HELRO	DUF4206 domain-containing protein. (124 aa)
	T1EJS2_HELRO	RGS domain-containing protein. (130 aa)
	T1EJT4_HELRO	Uncharacterized protein. (103 aa)
	T1ELX7_HELRO	Uncharacterized protein. (94 aa)
	T1EM55_HELRO	Uncharacterized protein. (231 aa)
	T1EQJ8_HELRO	Uncharacterized protein. (807 aa)
	T1ER48_HELRO	Uncharacterized protein. (380 aa)
	T1ERF9_HELRO	Uncharacterized protein. (297 aa)
	T1EU06_HELRO	Uncharacterized protein. (201 aa)
	T1EWF3_HELRO	Uncharacterized protein. (585 aa)
	T1EXC4_HELRO	Vps5 domain-containing protein. (185 aa)
	T1EYV2_HELRO	Uncharacterized protein. (194 aa)
	T1EZN7_HELRO	Uncharacterized protein. (1778 aa)
	T1EZV7_HELRO	Uncharacterized protein. (910 aa)
	T1F0K1_HELRO	ATG11 domain-containing protein. (173 aa)
	T1F8G5_HELRO	Uncharacterized protein. (581 aa)
	T1F9Z3_HELRO	PXA domain-containing protein. (235 aa)
	T1FM26_HELRO	Uncharacterized protein. (489 aa)
	T1FM55_HELRO	Uncharacterized protein. (322 aa)
	T1FMC6_HELRO	Prohibitin. (301 aa)
	T1FME2_HELRO	Uncharacterized protein. (209 aa)
	T1FMH6_HELRO	Autophagy-related protein 3. (340 aa)
	T1FMU2_HELRO	Uncharacterized protein. (347 aa)
	T1FNA1_HELRO	Uncharacterized protein. (205 aa)
	T1FNB8_HELRO	ANAPC4_WD40 domain-containing protein. (424 aa)
	T1FNG1_HELRO	Uncharacterized protein. (368 aa)
	T1FPA4_HELRO	Uncharacterized protein. (1281 aa)
	T1FPN6_HELRO	WD_REPEATS_REGION domain-containing protein. (338 aa)
	T1FR39_HELRO	Uncharacterized protein. (634 aa)
	T1FR86_HELRO	CNH domain-containing protein. (484 aa)
	T1FRD6_HELRO	PX domain-containing protein. (283 aa)
	T1FS14_HELRO	Uncharacterized protein. (386 aa)
	T1FS72_HELRO	Uncharacterized protein. (390 aa)
	T1FSR1_HELRO	Uncharacterized protein. (218 aa)
	T1FSV5_HELRO	Protein kinase domain-containing protein. (672 aa)
	T1FTR8_HELRO	Uncharacterized protein. (2502 aa)
	T1FU42_HELRO	Chorein_N domain-containing protein. (1370 aa)
	T1FU52_HELRO	Uncharacterized protein. (410 aa)
	T1FU53_HELRO	Uncharacterized protein. (1255 aa)
	T1FU82_HELRO	Uncharacterized protein. (2140 aa)
	T1FWX7_HELRO	Uncharacterized protein. (106 aa)
	T1FY85_HELRO	Autophagy protein 5; Involved in autophagic vesicle formation. (268 aa)
	T1FYQ6_HELRO	Protein kinase domain-containing protein. (211 aa)
	T1FZ92_HELRO	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (86 aa)
	T1FZQ9_HELRO	Uncharacterized protein. (192 aa)
	T1G0G5_HELRO	Uncharacterized protein. (117 aa)
	T1G1N0_HELRO	Protein kinase domain-containing protein. (182 aa)
	T1G2I8_HELRO	t-SNARE coiled-coil homology domain-containing protein. (223 aa)
	T1G3D7_HELRO	Uncharacterized protein. (424 aa)
	T1G3G7_HELRO	Uncharacterized protein. (68 aa)
	T1G531_HELRO	Uncharacterized protein. (234 aa)
	T1G542_HELRO	PX domain-containing protein. (363 aa)
	T1G6K0_HELRO	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (613 aa)
	T1G7Q9_HELRO	Uncharacterized protein. (335 aa)
	T1G7Z7_HELRO	Uncharacterized protein. (253 aa)
	T1G8V9_HELRO	Uncharacterized protein. (121 aa)
	T1G994_HELRO	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (718 aa)
	T1G9V0_HELRO	WD_REPEATS_REGION domain-containing protein. (551 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1ED30_HELRO	T1EDQ8_HELRO	T1ED30	T1EDQ8	ATG_C domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.542
T1ED30_HELRO	T1EEA0_HELRO	T1ED30	T1EEA0	ATG_C domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.677
T1ED30_HELRO	T1EFP5_HELRO	T1ED30	T1EFP5	ATG_C domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.542
T1ED30_HELRO	T1EM55_HELRO	T1ED30	T1EM55	ATG_C domain-containing protein.	Uncharacterized protein.	0.532
T1ED30_HELRO	T1F0K1_HELRO	T1ED30	T1F0K1	ATG_C domain-containing protein.	ATG11 domain-containing protein.	0.437
T1ED30_HELRO	T1FM26_HELRO	T1ED30	T1FM26	ATG_C domain-containing protein.	Uncharacterized protein.	0.449
T1ED30_HELRO	T1FMH6_HELRO	T1ED30	T1FMH6	ATG_C domain-containing protein.	Autophagy-related protein 3.	0.542
T1ED30_HELRO	T1FMU2_HELRO	T1ED30	T1FMU2	ATG_C domain-containing protein.	Uncharacterized protein.	0.571
T1ED30_HELRO	T1FNB8_HELRO	T1ED30	T1FNB8	ATG_C domain-containing protein.	ANAPC4_WD40 domain-containing protein.	0.971
T1ED30_HELRO	T1FNG1_HELRO	T1ED30	T1FNG1	ATG_C domain-containing protein.	Uncharacterized protein.	0.571
T1ED30_HELRO	T1FPA4_HELRO	T1ED30	T1FPA4	ATG_C domain-containing protein.	Uncharacterized protein.	0.562
T1ED30_HELRO	T1FR39_HELRO	T1ED30	T1FR39	ATG_C domain-containing protein.	Uncharacterized protein.	0.971
T1ED30_HELRO	T1FS14_HELRO	T1ED30	T1FS14	ATG_C domain-containing protein.	Uncharacterized protein.	0.437
T1ED30_HELRO	T1FSV5_HELRO	T1ED30	T1FSV5	ATG_C domain-containing protein.	Protein kinase domain-containing protein.	0.721
T1ED30_HELRO	T1FU42_HELRO	T1ED30	T1FU42	ATG_C domain-containing protein.	Chorein_N domain-containing protein.	0.960
T1ED30_HELRO	T1FY85_HELRO	T1ED30	T1FY85	ATG_C domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.548
T1ED30_HELRO	T1FYQ6_HELRO	T1ED30	T1FYQ6	ATG_C domain-containing protein.	Protein kinase domain-containing protein.	0.970
T1ED30_HELRO	T1FZ92_HELRO	T1ED30	T1FZ92	ATG_C domain-containing protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.542
T1ED30_HELRO	T1G1N0_HELRO	T1ED30	T1G1N0	ATG_C domain-containing protein.	Protein kinase domain-containing protein.	0.970
T1ED30_HELRO	T1G3D7_HELRO	T1ED30	T1G3D7	ATG_C domain-containing protein.	Uncharacterized protein.	0.542