(92 nodes) Protein kinase regulator activity network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1FKV4_HELRO	Radical_SAM_C domain-containing protein. (149 aa)
	T1FM95_HELRO	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (82 aa)
	T1FMF1_HELRO	Uncharacterized protein. (216 aa)
	T1FMK8_HELRO	Uncharacterized protein. (508 aa)
	T1FMU8_HELRO	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (116 aa)
	T1FRR0_HELRO	FOP_dimer domain-containing protein. (431 aa)
	T1FRI0_HELRO	Uncharacterized protein. (336 aa)
	T1FRH5_HELRO	CYCLIN domain-containing protein; Belongs to the cyclin family. (380 aa)
	T1FR06_HELRO	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (358 aa)
	T1FQX3_HELRO	Uncharacterized protein. (394 aa)
	T1FPU0_HELRO	BTB domain-containing protein. (191 aa)
	T1FPT9_HELRO	BTB domain-containing protein. (714 aa)
	T1FP87_HELRO	Uncharacterized protein. (372 aa)
	T1FP46_HELRO	CYCLIN domain-containing protein; Belongs to the cyclin family. (355 aa)
	T1FNW1_HELRO	RING-type domain-containing protein. (314 aa)
	T1FNQ9_HELRO	Uncharacterized protein; Belongs to the cyclin family. (511 aa)
	T1FN99_HELRO	Uncharacterized protein. (341 aa)
	T1FN83_HELRO	Uncharacterized protein. (399 aa)
	T1FRY9_HELRO	Uncharacterized protein. (725 aa)
	T1FS53_HELRO	Uncharacterized protein; Belongs to the cyclin family. (304 aa)
	T1FSI2_HELRO	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (159 aa)
	T1FT09_HELRO	Uncharacterized protein. (1502 aa)
	T1FT17_HELRO	Uncharacterized protein. (3098 aa)
	T1FU83_HELRO	TPX2 domain-containing protein. (611 aa)
	T1FUD2_HELRO	Uncharacterized protein. (538 aa)
	T1FUG5_HELRO	Uncharacterized protein. (1440 aa)
	T1FUH3_HELRO	INCENP_ARK-bind domain-containing protein. (1692 aa)
	T1FUM1_HELRO	Uncharacterized protein. (1967 aa)
	T1FWC4_HELRO	Uncharacterized protein. (215 aa)
	T1FX38_HELRO	Uncharacterized protein. (316 aa)
	T1FXG0_HELRO	Protein kinase domain-containing protein. (262 aa)
	T1FXL5_HELRO	Uncharacterized protein. (187 aa)
	T1FYW2_HELRO	Poly [ADP-ribose] polymerase. (288 aa)
	T1FZE6_HELRO	Uncharacterized protein; Belongs to the cyclin family. (339 aa)
	T1FZM7_HELRO	CYCLIN domain-containing protein; Belongs to the cyclin family. (265 aa)
	T1G022_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (252 aa)
	T1G0Q6_HELRO	Raptor_N domain-containing protein. (401 aa)
	T1G0U3_HELRO	Uncharacterized protein. (305 aa)
	T1G0Y2_HELRO	Uncharacterized protein. (369 aa)
	T1G283_HELRO	Uncharacterized protein. (342 aa)
	T1G303_HELRO	Uncharacterized protein. (178 aa)
	T1G4A2_HELRO	N-acetyltransferase domain-containing protein. (438 aa)
	T1G4A8_HELRO	Diacylglycerol kinase. (927 aa)
	T1G5R5_HELRO	Uncharacterized protein. (139 aa)
	T1G650_HELRO	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (182 aa)
	T1G6N7_HELRO	Uncharacterized protein; Belongs to the cyclin family. (290 aa)
	T1G751_HELRO	Uncharacterized protein. (313 aa)
	T1G7G7_HELRO	Uncharacterized protein. (361 aa)
	T1G7H5_HELRO	Uncharacterized protein. (362 aa)
	T1G8D7_HELRO	Cyclin N-terminal domain-containing protein. (217 aa)
	T1G7V9_HELRO	CYCLIN domain-containing protein; Belongs to the cyclin family. (233 aa)
	T1G8G9_HELRO	Cyclin_C domain-containing protein. (178 aa)
	T1G911_HELRO	Protein kinase domain-containing protein. (510 aa)
	T1G971_HELRO	Uncharacterized protein; Belongs to the cyclin family. (361 aa)
	T1FJT8_HELRO	Cyclin_C domain-containing protein. (134 aa)
	T1FE22_HELRO	Uncharacterized protein. (359 aa)
	T1FE20_HELRO	Uncharacterized protein. (714 aa)
	T1FAL1_HELRO	Uncharacterized protein. (852 aa)
	T1F8N9_HELRO	Uncharacterized protein. (353 aa)
	T1F6W9_HELRO	C2H2-type domain-containing protein. (2959 aa)
	T1F5J4_HELRO	Uncharacterized protein. (377 aa)
	T1F5E2_HELRO	RICTOR_N domain-containing protein. (274 aa)
	T1F5E1_HELRO	RICTOR_N domain-containing protein. (237 aa)
	T1F2J4_HELRO	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (254 aa)
	T1EYM9_HELRO	Uncharacterized protein. (159 aa)
	T1EXV3_HELRO	Uncharacterized protein. (522 aa)
	T1EVP1_HELRO	Uncharacterized protein. (777 aa)
	T1EV89_HELRO	VPS9 domain-containing protein. (253 aa)
	T1EKN2_HELRO	Uncharacterized protein. (130 aa)
	T1EKF3_HELRO	Uncharacterized protein. (293 aa)
	T1EJC5_HELRO	Uncharacterized protein. (152 aa)
	T1EJC4_HELRO	Protein kinase domain-containing protein. (199 aa)
	T1EJ64_HELRO	Protein kinase domain-containing protein. (220 aa)
	T1EIG0_HELRO	Uncharacterized protein. (152 aa)
	T1EHX4_HELRO	Uncharacterized protein; Belongs to the cyclin family. (277 aa)
	T1EGL2_HELRO	RIIa domain-containing protein. (97 aa)
	T1EGC7_HELRO	Cyclin A; Belongs to the cyclin family. (430 aa)
	T1EFL3_HELRO	Uncharacterized protein. (418 aa)
	T1EEY2_HELRO	Protein kinase domain-containing protein. (353 aa)
	T1EEQ9_HELRO	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (404 aa)
	T1EEN1_HELRO	Uncharacterized protein. (1152 aa)
	T1EEK6_HELRO	Uncharacterized protein. (381 aa)
	T1EEJ4_HELRO	Uncharacterized protein. (359 aa)
	T1EEC4_HELRO	CYCLIN domain-containing protein; Belongs to the cyclin family. (283 aa)
	T1EEA7_HELRO	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (619 aa)
	T1EE81_HELRO	TOG domain-containing protein. (2450 aa)
	T1EE28_HELRO	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (367 aa)
	T1EE16_HELRO	WD_REPEATS_REGION domain-containing protein. (325 aa)
	T1EDZ9_HELRO	Uncharacterized protein. (217 aa)
	T1EDZ5_HELRO	ANK_REP_REGION domain-containing protein. (587 aa)
	T1EDP6_HELRO	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (222 aa)
	T1FKI5_HELRO	Uncharacterized protein. (917 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EE16_HELRO	T1EE81_HELRO	T1EE16	T1EE81	WD_REPEATS_REGION domain-containing protein.	TOG domain-containing protein.	0.435
T1EE16_HELRO	T1EJ64_HELRO	T1EE16	T1EJ64	WD_REPEATS_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.444
T1EE16_HELRO	T1EYM9_HELRO	T1EE16	T1EYM9	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.986
T1EE16_HELRO	T1F5E1_HELRO	T1EE16	T1F5E1	WD_REPEATS_REGION domain-containing protein.	RICTOR_N domain-containing protein.	0.976
T1EE16_HELRO	T1F5E2_HELRO	T1EE16	T1F5E2	WD_REPEATS_REGION domain-containing protein.	RICTOR_N domain-containing protein.	0.967
T1EE16_HELRO	T1FXG0_HELRO	T1EE16	T1FXG0	WD_REPEATS_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.444
T1EE16_HELRO	T1G022_HELRO	T1EE16	T1G022	WD_REPEATS_REGION domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.445
T1EE16_HELRO	T1G0Q6_HELRO	T1EE16	T1G0Q6	WD_REPEATS_REGION domain-containing protein.	Raptor_N domain-containing protein.	0.986
T1EE16_HELRO	T1G911_HELRO	T1EE16	T1G911	WD_REPEATS_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.445
T1EE28_HELRO	T1EEQ9_HELRO	T1EE28	T1EEQ9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.585
T1EE28_HELRO	T1EGC7_HELRO	T1EE28	T1EGC7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin A; Belongs to the cyclin family.	0.805
T1EE28_HELRO	T1F2J4_HELRO	T1EE28	T1F2J4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.603
T1EE28_HELRO	T1F5J4_HELRO	T1EE28	T1F5J4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.564
T1EE28_HELRO	T1FE20_HELRO	T1EE28	T1FE20	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.501
T1EE28_HELRO	T1FE22_HELRO	T1EE28	T1FE22	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.501
T1EE28_HELRO	T1FJT8_HELRO	T1EE28	T1FJT8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin_C domain-containing protein.	0.546
T1EE28_HELRO	T1FM95_HELRO	T1EE28	T1FM95	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.869
T1EE28_HELRO	T1FNQ9_HELRO	T1EE28	T1FNQ9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.904
T1EE28_HELRO	T1FNW1_HELRO	T1EE28	T1FNW1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	RING-type domain-containing protein.	0.495
T1EE28_HELRO	T1FT09_HELRO	T1EE28	T1FT09	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.478