(25 nodes) Negative regulation of MAPK cascade network (Helobdella robusta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1EDW7_HELRO	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (236 aa)
	T1EEC8_HELRO	UDENN FLCN/SMCR8-type domain-containing protein. (597 aa)
	T1EGN5_HELRO	Uncharacterized protein. (260 aa)
	T1EH25_HELRO	Uncharacterized protein. (173 aa)
	T1EHE9_HELRO	WH1 domain-containing protein. (118 aa)
	T1EIM7_HELRO	Uncharacterized protein. (82 aa)
	T1EJX7_HELRO	Uncharacterized protein. (64 aa)
	T1EKD6_HELRO	Uncharacterized protein. (256 aa)
	T1EVP1_HELRO	Uncharacterized protein. (777 aa)
	T1F6R0_HELRO	Uncharacterized protein. (143 aa)
	T1FAB5_HELRO	WH1 domain-containing protein. (748 aa)
	T1FIS4_HELRO	Sortilin-Vps10 domain-containing protein. (246 aa)
	T1FMG7_HELRO	Uncharacterized protein. (561 aa)
	T1FT15_HELRO	Uncharacterized protein. (478 aa)
	T1FUD2_HELRO	Uncharacterized protein. (538 aa)
	T1FWB1_HELRO	VPS10 domain-containing protein. (2037 aa)
	T1FWH4_HELRO	Uncharacterized protein. (557 aa)
	T1FYG5_HELRO	USP domain-containing protein. (371 aa)
	T1FYR1_HELRO	Uncharacterized protein. (367 aa)
	T1FZD7_HELRO	Uncharacterized protein. (254 aa)
	T1G0Q8_HELRO	WH1 domain-containing protein. (360 aa)
	T1G132_HELRO	Uncharacterized protein. (283 aa)
	T1G3F2_HELRO	Uncharacterized protein. (144 aa)
	T1G3U8_HELRO	Uncharacterized protein. (267 aa)
	T1G6H8_HELRO	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (376 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EDW7_HELRO	T1FIS4_HELRO	T1EDW7	T1FIS4	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Sortilin-Vps10 domain-containing protein.	0.416
T1EDW7_HELRO	T1FWB1_HELRO	T1EDW7	T1FWB1	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	VPS10 domain-containing protein.	0.416
T1EH25_HELRO	T1FIS4_HELRO	T1EH25	T1FIS4	Uncharacterized protein.	Sortilin-Vps10 domain-containing protein.	0.416
T1EH25_HELRO	T1FWB1_HELRO	T1EH25	T1FWB1	Uncharacterized protein.	VPS10 domain-containing protein.	0.416
T1EH25_HELRO	T1G3U8_HELRO	T1EH25	T1G3U8	Uncharacterized protein.	Uncharacterized protein.	0.462
T1FIS4_HELRO	T1EDW7_HELRO	T1FIS4	T1EDW7	Sortilin-Vps10 domain-containing protein.	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.416
T1FIS4_HELRO	T1EH25_HELRO	T1FIS4	T1EH25	Sortilin-Vps10 domain-containing protein.	Uncharacterized protein.	0.416
T1FIS4_HELRO	T1FT15_HELRO	T1FIS4	T1FT15	Sortilin-Vps10 domain-containing protein.	Uncharacterized protein.	0.429
T1FIS4_HELRO	T1FWH4_HELRO	T1FIS4	T1FWH4	Sortilin-Vps10 domain-containing protein.	Uncharacterized protein.	0.418
T1FIS4_HELRO	T1G3F2_HELRO	T1FIS4	T1G3F2	Sortilin-Vps10 domain-containing protein.	Uncharacterized protein.	0.429
T1FIS4_HELRO	T1G3U8_HELRO	T1FIS4	T1G3U8	Sortilin-Vps10 domain-containing protein.	Uncharacterized protein.	0.416
T1FIS4_HELRO	T1G6H8_HELRO	T1FIS4	T1G6H8	Sortilin-Vps10 domain-containing protein.	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.416
T1FT15_HELRO	T1FIS4_HELRO	T1FT15	T1FIS4	Uncharacterized protein.	Sortilin-Vps10 domain-containing protein.	0.429
T1FT15_HELRO	T1FWB1_HELRO	T1FT15	T1FWB1	Uncharacterized protein.	VPS10 domain-containing protein.	0.429
T1FWB1_HELRO	T1EDW7_HELRO	T1FWB1	T1EDW7	VPS10 domain-containing protein.	Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.416
T1FWB1_HELRO	T1EH25_HELRO	T1FWB1	T1EH25	VPS10 domain-containing protein.	Uncharacterized protein.	0.416
T1FWB1_HELRO	T1FT15_HELRO	T1FWB1	T1FT15	VPS10 domain-containing protein.	Uncharacterized protein.	0.429
T1FWB1_HELRO	T1FWH4_HELRO	T1FWB1	T1FWH4	VPS10 domain-containing protein.	Uncharacterized protein.	0.418
T1FWB1_HELRO	T1G3F2_HELRO	T1FWB1	T1G3F2	VPS10 domain-containing protein.	Uncharacterized protein.	0.429
T1FWB1_HELRO	T1G3U8_HELRO	T1FWB1	T1G3U8	VPS10 domain-containing protein.	Uncharacterized protein.	0.416