(21 nodes) Polyol biosynthetic process network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1G7K9_HELRO	Sepiapterin reductase. (277 aa)
	T1EE02_HELRO	Uncharacterized protein. (635 aa)
	T1EE40_HELRO	DAGKc domain-containing protein. (347 aa)
	T1EEI9_HELRO	Aminotran_1_2 domain-containing protein. (495 aa)
	T1EEN3_HELRO	Neutral ceramidase. (721 aa)
	T1EEQ7_HELRO	Uncharacterized protein. (630 aa)
	T1EKD8_HELRO	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (468 aa)
	T1ELZ8_HELRO	Uncharacterized protein. (642 aa)
	T1EMJ5_HELRO	Aminotran_1_2 domain-containing protein. (378 aa)
	T1EN59_HELRO	Kinase; Belongs to the inositol phosphokinase (IPK) family. (303 aa)
	T1EQQ3_HELRO	Kinase; Belongs to the inositol phosphokinase (IPK) family. (330 aa)
	T1EZ60_HELRO	Uncharacterized protein. (102 aa)
	T1FL85_HELRO	Kinase; Belongs to the inositol phosphokinase (IPK) family. (465 aa)
	T1FP76_HELRO	GTP_cyclohydroI domain-containing protein. (372 aa)
	T1FVC8_HELRO	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (454 aa)
	T1FYA4_HELRO	Uncharacterized protein. (237 aa)
	T1G0Y7_HELRO	Uncharacterized protein. (150 aa)
	T1G3I9_HELRO	Uncharacterized protein. (386 aa)
	T1G6X6_HELRO	Uncharacterized protein. (645 aa)
	T1G6Y7_HELRO	Kinase; Belongs to the inositol phosphokinase (IPK) family. (287 aa)
	T1G750_HELRO	Inositol-1-monophosphatase. (254 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EE02_HELRO	T1EEQ7_HELRO	T1EE02	T1EEQ7	Uncharacterized protein.	Uncharacterized protein.	0.803
T1EE02_HELRO	T1ELZ8_HELRO	T1EE02	T1ELZ8	Uncharacterized protein.	Uncharacterized protein.	0.806
T1EE02_HELRO	T1EMJ5_HELRO	T1EE02	T1EMJ5	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.823
T1EE02_HELRO	T1G6X6_HELRO	T1EE02	T1G6X6	Uncharacterized protein.	Uncharacterized protein.	0.803
T1EE40_HELRO	T1EEI9_HELRO	T1EE40	T1EEI9	DAGKc domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.689
T1EE40_HELRO	T1EEN3_HELRO	T1EE40	T1EEN3	DAGKc domain-containing protein.	Neutral ceramidase.	0.971
T1EEI9_HELRO	T1EE40_HELRO	T1EEI9	T1EE40	Aminotran_1_2 domain-containing protein.	DAGKc domain-containing protein.	0.689
T1EEI9_HELRO	T1EEN3_HELRO	T1EEI9	T1EEN3	Aminotran_1_2 domain-containing protein.	Neutral ceramidase.	0.671
T1EEN3_HELRO	T1EE40_HELRO	T1EEN3	T1EE40	Neutral ceramidase.	DAGKc domain-containing protein.	0.971
T1EEN3_HELRO	T1EEI9_HELRO	T1EEN3	T1EEI9	Neutral ceramidase.	Aminotran_1_2 domain-containing protein.	0.671
T1EEQ7_HELRO	T1EE02_HELRO	T1EEQ7	T1EE02	Uncharacterized protein.	Uncharacterized protein.	0.803
T1EEQ7_HELRO	T1ELZ8_HELRO	T1EEQ7	T1ELZ8	Uncharacterized protein.	Uncharacterized protein.	0.805
T1EEQ7_HELRO	T1EMJ5_HELRO	T1EEQ7	T1EMJ5	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.823
T1EEQ7_HELRO	T1G6X6_HELRO	T1EEQ7	T1G6X6	Uncharacterized protein.	Uncharacterized protein.	0.803
T1EKD8_HELRO	T1EN59_HELRO	T1EKD8	T1EN59	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.405
T1EKD8_HELRO	T1FL85_HELRO	T1EKD8	T1FL85	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.962
T1EKD8_HELRO	T1FVC8_HELRO	T1EKD8	T1FVC8	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).	0.460
T1EKD8_HELRO	T1G3I9_HELRO	T1EKD8	T1G3I9	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Uncharacterized protein.	0.947
T1ELZ8_HELRO	T1EE02_HELRO	T1ELZ8	T1EE02	Uncharacterized protein.	Uncharacterized protein.	0.806
T1ELZ8_HELRO	T1EEQ7_HELRO	T1ELZ8	T1EEQ7	Uncharacterized protein.	Uncharacterized protein.	0.805