(105 nodes) Perinuclear region of cytoplasm network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1EVS7_HELRO	Uncharacterized protein. (712 aa)
	T1EVQ5_HELRO	Uncharacterized protein. (226 aa)
	T1EUD9_HELRO	Atx10homo_assoc domain-containing protein. (535 aa)
	T1EU44_HELRO	Uncharacterized protein. (174 aa)
	T1ERM2_HELRO	Uncharacterized protein. (233 aa)
	T1EPN4_HELRO	RabBD domain-containing protein. (376 aa)
	T1EPD6_HELRO	BZIP domain-containing protein. (543 aa)
	T1EMI8_HELRO	HATPase_c domain-containing protein. (729 aa)
	T1EMI5_HELRO	SEC7 domain-containing protein. (1575 aa)
	T1EMF5_HELRO	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (295 aa)
	T1EM86_HELRO	SAC domain-containing protein. (1080 aa)
	T1EM75_HELRO	HATPase_c domain-containing protein. (736 aa)
	T1ELV8_HELRO	AAA domain-containing protein. (404 aa)
	T1ELN7_HELRO	Ubiquitin carboxyl-terminal hydrolase. (830 aa)
	T1EKY7_HELRO	Syntaxin-6_N domain-containing protein. (69 aa)
	T1EKC8_HELRO	PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (329 aa)
	T1EK09_HELRO	Nanos-type domain-containing protein; Belongs to the nanos family. (53 aa)
	T1EJX2_HELRO	PDEase domain-containing protein. (85 aa)
	T1EJT4_HELRO	Uncharacterized protein. (103 aa)
	T1EIY3_HELRO	PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (445 aa)
	T1EHB1_HELRO	Uncharacterized protein. (116 aa)
	T1EGE1_HELRO	Sortilin. (618 aa)
	T1EG78_HELRO	GP-PDE domain-containing protein. (450 aa)
	T1EFZ6_HELRO	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (586 aa)
	T1EF46_HELRO	Uncharacterized protein. (402 aa)
	T1EF09_HELRO	TPR_REGION domain-containing protein. (940 aa)
	T1EEY5_HELRO	Uncharacterized protein. (1226 aa)
	T1EER9_HELRO	PH domain-containing protein. (729 aa)
	T1EER3_HELRO	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (542 aa)
	T1EEJ7_HELRO	Uncharacterized protein. (709 aa)
	T1EEG5_HELRO	ENTH domain-containing protein. (411 aa)
	T1EEC2_HELRO	Phosphodiesterase. (475 aa)
	T1EDC5_HELRO	Uncharacterized protein. (602 aa)
	T1G3D4_HELRO	Uncharacterized protein. (141 aa)
	T1G303_HELRO	Uncharacterized protein. (178 aa)
	T1G2T5_HELRO	Phosphodiesterase. (552 aa)
	T1G2P4_HELRO	Phosphodiesterase. (491 aa)
	T1G203_HELRO	Uncharacterized protein. (359 aa)
	T1G1H6_HELRO	Uncharacterized protein. (202 aa)
	T1G152_HELRO	Vps53_N domain-containing protein. (840 aa)
	T1G0U2_HELRO	Uncharacterized protein. (371 aa)
	T1G0C4_HELRO	Phosphodiesterase. (548 aa)
	T1FZP7_HELRO	Uncharacterized protein. (108 aa)
	T1FZJ4_HELRO	HORMA domain-containing protein. (177 aa)
	T1FYW7_HELRO	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (232 aa)
	T1FYT6_HELRO	BH4_AAA_HYDROXYL_2 domain-containing protein. (336 aa)
	T1FYR1_HELRO	Uncharacterized protein. (367 aa)
	T1FYQ5_HELRO	Uncharacterized protein. (174 aa)
	T1FYG5_HELRO	USP domain-containing protein. (371 aa)
	T1FWX5_HELRO	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (609 aa)
	T1FWM1_HELRO	Uncharacterized protein. (925 aa)
	T1FWF3_HELRO	PH domain-containing protein. (627 aa)
	T1FVQ3_HELRO	Uncharacterized protein. (745 aa)
	T1FVF3_HELRO	PDZ domain-containing protein. (129 aa)
	T1FV48_HELRO	Uncharacterized protein. (1397 aa)
	T1FV23_HELRO	Uncharacterized protein. (492 aa)
	T1FTP1_HELRO	BZIP domain-containing protein. (458 aa)
	T1FRX3_HELRO	Uncharacterized protein. (526 aa)
	T1FRV0_HELRO	TYR_PHOSPHATASE_2 domain-containing protein. (643 aa)
	T1FRR0_HELRO	FOP_dimer domain-containing protein. (431 aa)
	T1FRD5_HELRO	RanGAP1_C domain-containing protein. (551 aa)
	T1FQW0_HELRO	JmjC domain-containing protein. (364 aa)
	T1FPY7_HELRO	Methyltransf_21 domain-containing protein. (313 aa)
	T1FPQ0_HELRO	Btz domain-containing protein. (1765 aa)
	T1FPF9_HELRO	Uncharacterized protein. (1143 aa)
	T1FPB1_HELRO	Uncharacterized protein. (430 aa)
	T1FNW8_HELRO	ANK_REP_REGION domain-containing protein. (121 aa)
	T1FNL9_HELRO	Uncharacterized protein. (212 aa)
	T1FNI6_HELRO	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (770 aa)
	T1FNF4_HELRO	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (308 aa)
	T1FN04_HELRO	Uncharacterized protein. (276 aa)
	T1FMN3_HELRO	Uncharacterized protein. (454 aa)
	T1G3S2_HELRO	Uncharacterized protein. (968 aa)
	T1FML4_HELRO	Uncharacterized protein. (282 aa)
	T1FMD3_HELRO	Uncharacterized protein. (209 aa)
	T1FKE6_HELRO	Methyltransf_21 domain-containing protein. (284 aa)
	T1FKE5_HELRO	Methyltransf_21 domain-containing protein. (281 aa)
	T1FFN9_HELRO	UBX domain-containing protein. (449 aa)
	T1FFJ5_HELRO	SURP motif domain-containing protein. (751 aa)
	T1FED7_HELRO	Uncharacterized protein. (163 aa)
	T1FDW1_HELRO	GRIP domain-containing protein. (327 aa)
	T1FB67_HELRO	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (544 aa)
	T1FAJ5_HELRO	Methyltransf_21 domain-containing protein. (322 aa)
	T1F8V8_HELRO	Methyltransf_21 domain-containing protein. (234 aa)
	T1F8U4_HELRO	SURP motif domain-containing protein. (290 aa)
	T1F717_HELRO	Methyltransf_21 domain-containing protein. (264 aa)
	T1F705_HELRO	Uncharacterized protein. (139 aa)
	T1F702_HELRO	Methyltransf_21 domain-containing protein. (297 aa)
	T1F6R0_HELRO	Uncharacterized protein. (143 aa)
	T1F3D7_HELRO	Uncharacterized protein. (282 aa)
	T1F347_HELRO	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1226 aa)
	T1F2H7_HELRO	RabBD domain-containing protein. (444 aa)
	T1F2H0_HELRO	Uncharacterized protein. (113 aa)
	T1EY34_HELRO	Uncharacterized protein. (124 aa)
	T1EXF8_HELRO	Btz domain-containing protein. (1389 aa)
	T1EXD8_HELRO	Uncharacterized protein. (306 aa)
	T1G9G6_HELRO	PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (283 aa)
	T1G830_HELRO	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (557 aa)
	T1G812_HELRO	Uncharacterized protein. (243 aa)
	T1G7S4_HELRO	Uncharacterized protein. (983 aa)
	T1G6P3_HELRO	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (386 aa)
	T1G6M7_HELRO	Uncharacterized protein. (409 aa)
	T1G6K0_HELRO	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (613 aa)
	T1G5W2_HELRO	Uncharacterized protein. (343 aa)
	T1G547_HELRO	GBD/FH3 domain-containing protein. (228 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EDC5_HELRO	T1EKY7_HELRO	T1EDC5	T1EKY7	Uncharacterized protein.	Syntaxin-6_N domain-containing protein.	0.809
T1EDC5_HELRO	T1FDW1_HELRO	T1EDC5	T1FDW1	Uncharacterized protein.	GRIP domain-containing protein.	0.408
T1EDC5_HELRO	T1FMD3_HELRO	T1EDC5	T1FMD3	Uncharacterized protein.	Uncharacterized protein.	0.415
T1EDC5_HELRO	T1FNF4_HELRO	T1EDC5	T1FNF4	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.866
T1EDC5_HELRO	T1FNL9_HELRO	T1EDC5	T1FNL9	Uncharacterized protein.	Uncharacterized protein.	0.415
T1EDC5_HELRO	T1FV48_HELRO	T1EDC5	T1FV48	Uncharacterized protein.	Uncharacterized protein.	0.647
T1EDC5_HELRO	T1FYW7_HELRO	T1EDC5	T1FYW7	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.809
T1EDC5_HELRO	T1G152_HELRO	T1EDC5	T1G152	Uncharacterized protein.	Vps53_N domain-containing protein.	0.998
T1EEG5_HELRO	T1FWM1_HELRO	T1EEG5	T1FWM1	ENTH domain-containing protein.	Uncharacterized protein.	0.652
T1EEJ7_HELRO	T1FWM1_HELRO	T1EEJ7	T1FWM1	Uncharacterized protein.	Uncharacterized protein.	0.626
T1EEY5_HELRO	T1EXF8_HELRO	T1EEY5	T1EXF8	Uncharacterized protein.	Btz domain-containing protein.	0.500
T1EEY5_HELRO	T1F8U4_HELRO	T1EEY5	T1F8U4	Uncharacterized protein.	SURP motif domain-containing protein.	0.417
T1EEY5_HELRO	T1FFJ5_HELRO	T1EEY5	T1FFJ5	Uncharacterized protein.	SURP motif domain-containing protein.	0.417
T1EEY5_HELRO	T1FPQ0_HELRO	T1EEY5	T1FPQ0	Uncharacterized protein.	Btz domain-containing protein.	0.500
T1EF09_HELRO	T1EM75_HELRO	T1EF09	T1EM75	TPR_REGION domain-containing protein.	HATPase_c domain-containing protein.	0.707
T1EF09_HELRO	T1EMI8_HELRO	T1EF09	T1EMI8	TPR_REGION domain-containing protein.	HATPase_c domain-containing protein.	0.906
T1EFZ6_HELRO	T1FVQ3_HELRO	T1EFZ6	T1FVQ3	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.598
T1EFZ6_HELRO	T1G6P3_HELRO	T1EFZ6	T1G6P3	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.903
T1EGE1_HELRO	T1EJT4_HELRO	T1EGE1	T1EJT4	Sortilin.	Uncharacterized protein.	0.608
T1EGE1_HELRO	T1FV48_HELRO	T1EGE1	T1FV48	Sortilin.	Uncharacterized protein.	0.711