(30 nodes) Negative regulation of canonical Wnt signaling pathway network (Helobdella robusta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1FP37_HELRO	UBA domain-containing protein. (280 aa)
	T1FR54_HELRO	SAM domain-containing protein. (383 aa)
	T1FTH4_HELRO	Uncharacterized protein. (2007 aa)
	T1FXL3_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (323 aa)
	T1FY80_HELRO	Uncharacterized protein. (411 aa)
	T1FYG5_HELRO	USP domain-containing protein. (371 aa)
	T1FYR1_HELRO	Uncharacterized protein. (367 aa)
	T1FZH9_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (382 aa)
	T1G0D4_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (331 aa)
	T1G1B1_HELRO	RuvB-like helicase; Belongs to the RuvB family. (456 aa)
	T1G1P1_HELRO	DIX domain-containing protein. (110 aa)
	T1G4K4_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
	T1G6E7_HELRO	Protein kinase domain-containing protein. (316 aa)
	T1G6S6_HELRO	TLE_N domain-containing protein. (125 aa)
	T1ESK4_HELRO	FERM domain-containing protein. (432 aa)
	T1ESK3_HELRO	RING-type domain-containing protein. (583 aa)
	T1EL84_HELRO	DIX domain-containing protein. (80 aa)
	T1EK65_HELRO	HMG box domain-containing protein. (58 aa)
	T1EJ25_HELRO	Uncharacterized protein; Belongs to the protein kinase superfamily. (402 aa)
	T1EIG2_HELRO	RGS domain-containing protein. (134 aa)
	T1EHW7_HELRO	Uncharacterized protein. (395 aa)
	T1EDK4_HELRO	Protein kinase domain-containing protein. (379 aa)
	T1G6T6_HELRO	Uncharacterized protein. (336 aa)
	T1G9L8_HELRO	Uncharacterized protein. (375 aa)
	T1G9R0_HELRO	WD_REPEATS_REGION domain-containing protein. (345 aa)
	T1ET82_HELRO	Uncharacterized protein. (455 aa)
	T1F4F4_HELRO	TLE_N domain-containing protein. (193 aa)
	T1FEX9_HELRO	Uncharacterized protein. (125 aa)
	T1FM22_HELRO	Uncharacterized protein. (762 aa)
	T1FNW7_HELRO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EDK4_HELRO	T1EHW7_HELRO	T1EDK4	T1EHW7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.794
T1EDK4_HELRO	T1EIG2_HELRO	T1EDK4	T1EIG2	Protein kinase domain-containing protein.	RGS domain-containing protein.	0.798
T1EDK4_HELRO	T1EL84_HELRO	T1EDK4	T1EL84	Protein kinase domain-containing protein.	DIX domain-containing protein.	0.798
T1EDK4_HELRO	T1FNW7_HELRO	T1EDK4	T1FNW7	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.534
T1EDK4_HELRO	T1FTH4_HELRO	T1EDK4	T1FTH4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.794
T1EDK4_HELRO	T1FXL3_HELRO	T1EDK4	T1FXL3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.534
T1EDK4_HELRO	T1G0D4_HELRO	T1EDK4	T1G0D4	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.534
T1EDK4_HELRO	T1G1P1_HELRO	T1EDK4	T1G1P1	Protein kinase domain-containing protein.	DIX domain-containing protein.	0.798
T1EDK4_HELRO	T1G6E7_HELRO	T1EDK4	T1G6E7	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.534
T1EHW7_HELRO	T1EDK4_HELRO	T1EHW7	T1EDK4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.794
T1EHW7_HELRO	T1EIG2_HELRO	T1EHW7	T1EIG2	Uncharacterized protein.	RGS domain-containing protein.	0.833
T1EHW7_HELRO	T1EL84_HELRO	T1EHW7	T1EL84	Uncharacterized protein.	DIX domain-containing protein.	0.919
T1EHW7_HELRO	T1FNW7_HELRO	T1EHW7	T1FNW7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.566
T1EHW7_HELRO	T1FTH4_HELRO	T1EHW7	T1FTH4	Uncharacterized protein.	Uncharacterized protein.	0.540
T1EHW7_HELRO	T1FXL3_HELRO	T1EHW7	T1FXL3	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.566
T1EHW7_HELRO	T1FZH9_HELRO	T1EHW7	T1FZH9	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.794
T1EHW7_HELRO	T1G0D4_HELRO	T1EHW7	T1G0D4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.566
T1EHW7_HELRO	T1G1P1_HELRO	T1EHW7	T1G1P1	Uncharacterized protein.	DIX domain-containing protein.	0.919
T1EHW7_HELRO	T1G4K4_HELRO	T1EHW7	T1G4K4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.794
T1EHW7_HELRO	T1G6E7_HELRO	T1EHW7	T1G6E7	Uncharacterized protein.	Protein kinase domain-containing protein.	0.566