44 items (Helobdella robusta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1F9F3_HELRO	Uncharacterized protein. (384 aa)
	T1EDE2_HELRO	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (790 aa)
	T1EES6_HELRO	BRCT domain-containing protein. (410 aa)
	T1EHU7_HELRO	Uncharacterized protein. (484 aa)
	T1EI79_HELRO	Uncharacterized protein. (109 aa)
	T1EKH9_HELRO	MPN domain-containing protein. (264 aa)
	T1ELV7_HELRO	WD_REPEATS_REGION domain-containing protein. (300 aa)
	T1ENL0_HELRO	NUC194 domain-containing protein. (1382 aa)
	T1ER96_HELRO	Protein kinase domain-containing protein. (708 aa)
	T1EX14_HELRO	Uncharacterized protein. (2000 aa)
	T1EY35_HELRO	FCP1 homology domain-containing protein. (443 aa)
	T1EYD6_HELRO	Uncharacterized protein. (299 aa)
	T1F2R6_HELRO	Uncharacterized protein. (248 aa)
	T1F3D2_HELRO	WW domain-containing protein. (960 aa)
	T1FAH1_HELRO	Uncharacterized protein. (437 aa)
	T1FB67_HELRO	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (544 aa)
	T1FJ71_HELRO	Protein kinase domain-containing protein. (317 aa)
	T1FJN1_HELRO	F-box domain-containing protein. (382 aa)
	T1FJQ7_HELRO	Uncharacterized protein. (104 aa)
	T1FP02_HELRO	Checkpoint protein; Belongs to the HUS1 family. (283 aa)
	T1FPP5_HELRO	Uncharacterized protein. (531 aa)
	T1FQ99_HELRO	Uncharacterized protein. (408 aa)
	T1FQW8_HELRO	Protein kinase domain-containing protein. (579 aa)
	T1FR22_HELRO	Uncharacterized protein. (111 aa)
	T1FR23_HELRO	Uncharacterized protein. (345 aa)
	T1FR33_HELRO	Uncharacterized protein. (672 aa)
	T1FR47_HELRO	Uncharacterized protein. (779 aa)
	T1FRW9_HELRO	Uncharacterized protein. (1019 aa)
	T1FTS6_HELRO	BUB1 N-terminal domain-containing protein. (1612 aa)
	T1FU31_HELRO	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (756 aa)
	T1FU85_HELRO	TPR_MLP1_2 domain-containing protein. (2420 aa)
	T1FUP2_HELRO	Uncharacterized protein. (418 aa)
	T1FVJ3_HELRO	Uncharacterized protein. (679 aa)
	T1FVM1_HELRO	Uncharacterized protein. (1295 aa)
	T1FW96_HELRO	Rod_C domain-containing protein. (2611 aa)
	T1FWP7_HELRO	Uncharacterized protein. (787 aa)
	T1FWY9_HELRO	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (694 aa)
	T1FWZ3_HELRO	Uncharacterized protein. (273 aa)
	T1FXI8_HELRO	AAA domain-containing protein. (398 aa)
	T1FZJ4_HELRO	HORMA domain-containing protein. (177 aa)
	T1G305_HELRO	FCP1 homology domain-containing protein. (224 aa)
	T1G3E7_HELRO	G-patch domain-containing protein. (185 aa)
	T1G3Q5_HELRO	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (748 aa)
	T1G4M0_HELRO	Protein kinase domain-containing protein. (139 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EDE2_HELRO	T1EHU7_HELRO	T1EDE2	T1EHU7	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Uncharacterized protein.	0.534
T1EDE2_HELRO	T1ER96_HELRO	T1EDE2	T1ER96	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Protein kinase domain-containing protein.	0.639
T1EDE2_HELRO	T1FJQ7_HELRO	T1EDE2	T1FJQ7	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Uncharacterized protein.	0.540
T1EDE2_HELRO	T1FQW8_HELRO	T1EDE2	T1FQW8	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Protein kinase domain-containing protein.	0.836
T1EDE2_HELRO	T1FR47_HELRO	T1EDE2	T1FR47	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Uncharacterized protein.	0.886
T1EDE2_HELRO	T1FTS6_HELRO	T1EDE2	T1FTS6	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	BUB1 N-terminal domain-containing protein.	0.492
T1EDE2_HELRO	T1FW96_HELRO	T1EDE2	T1FW96	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Rod_C domain-containing protein.	0.634
T1EDE2_HELRO	T1FXI8_HELRO	T1EDE2	T1FXI8	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	AAA domain-containing protein.	0.999
T1EDE2_HELRO	T1FZJ4_HELRO	T1EDE2	T1FZJ4	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	HORMA domain-containing protein.	0.544
T1EDE2_HELRO	T1G4M0_HELRO	T1EDE2	T1G4M0	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Protein kinase domain-containing protein.	0.492
T1EES6_HELRO	T1EHU7_HELRO	T1EES6	T1EHU7	BRCT domain-containing protein.	Uncharacterized protein.	0.843
T1EES6_HELRO	T1FP02_HELRO	T1EES6	T1FP02	BRCT domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.821
T1EES6_HELRO	T1FQW8_HELRO	T1EES6	T1FQW8	BRCT domain-containing protein.	Protein kinase domain-containing protein.	0.818
T1EES6_HELRO	T1FR47_HELRO	T1EES6	T1FR47	BRCT domain-containing protein.	Uncharacterized protein.	0.790
T1EES6_HELRO	T1FRW9_HELRO	T1EES6	T1FRW9	BRCT domain-containing protein.	Uncharacterized protein.	0.900
T1EES6_HELRO	T1FU31_HELRO	T1EES6	T1FU31	BRCT domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.666
T1EES6_HELRO	T1FVM1_HELRO	T1EES6	T1FVM1	BRCT domain-containing protein.	Uncharacterized protein.	0.771
T1EES6_HELRO	T1FXI8_HELRO	T1EES6	T1FXI8	BRCT domain-containing protein.	AAA domain-containing protein.	0.555
T1EES6_HELRO	T1G3Q5_HELRO	T1EES6	T1G3Q5	BRCT domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.794
T1EHU7_HELRO	T1EDE2_HELRO	T1EHU7	T1EDE2	Uncharacterized protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.534