(140 nodes) S-adenosyl-L-methionine-dependent methyltransferase superfamily network (Helobdella robusta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1EF65_HELRO	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (337 aa)
	T1EF63_HELRO	Bin3-type SAM domain-containing protein. (289 aa)
	T1EEU9_HELRO	Uncharacterized protein. (306 aa)
	T1EEU2_HELRO	Uncharacterized protein. (220 aa)
	T1G555_HELRO	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (224 aa)
	T1G5Z3_HELRO	Uncharacterized protein. (148 aa)
	T1G6K7_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (439 aa)
	T1G6S8_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (314 aa)
	T1G782_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (345 aa)
	T1G7A0_HELRO	Uncharacterized protein. (153 aa)
	T1ENQ2_HELRO	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (727 aa)
	T1EKF4_HELRO	Adrift-type SAM-dependent 2'-O-MTase domain-containing protein. (377 aa)
	T1EKJ6_HELRO	Uncharacterized protein. (214 aa)
	T1G7E5_HELRO	Uncharacterized protein. (174 aa)
	T1FNJ6_HELRO	Fe-S cluster assembly protein DRE2. (260 aa)
	T1FNR4_HELRO	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (287 aa)
	T1FP27_HELRO	Methyltransf_11 domain-containing protein. (611 aa)
	T1FPD6_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (223 aa)
	T1FPG5_HELRO	Uncharacterized protein. (1072 aa)
	T1FPG8_HELRO	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (357 aa)
	T1FPY7_HELRO	Methyltransf_21 domain-containing protein. (313 aa)
	T1FRK7_HELRO	Uncharacterized protein. (418 aa)
	T1ELF8_HELRO	Methyltransf_11 domain-containing protein. (282 aa)
	T1G7F0_HELRO	FtsJ domain-containing protein. (250 aa)
	T1G7U5_HELRO	Uncharacterized protein. (208 aa)
	T1G896_HELRO	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. (255 aa)
	T1G9D9_HELRO	Methyltransf_11 domain-containing protein. (363 aa)
	T1G9P9_HELRO	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (568 aa)
	T1G9Q6_HELRO	Carrier domain-containing protein. (2553 aa)
	T1G7D1_HELRO	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (283 aa)
	T1ELF9_HELRO	Methyltransf_11 domain-containing protein. (311 aa)
	T1ELI1_HELRO	Methyltranfer_dom domain-containing protein. (284 aa)
	T1ELJ9_HELRO	Protein-L-isoaspartate O-methyltransferase. (234 aa)
	T1ELK2_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (327 aa)
	T1ELN3_HELRO	Bin3-type SAM domain-containing protein. (255 aa)
	T1ELQ0_HELRO	Methyltranfer_dom domain-containing protein. (217 aa)
	T1EM28_HELRO	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (293 aa)
	T1EEM3_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (497 aa)
	T1EEL7_HELRO	Uncharacterized protein. (202 aa)
	T1EDL3_HELRO	PABS domain-containing protein. (387 aa)
	T1ECX9_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (800 aa)
	T1EM91_HELRO	Uncharacterized protein. (154 aa)
	T1EMG8_HELRO	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (327 aa)
	T1EMH6_HELRO	tRNA (guanine(26)-N(2))-dimethyltransferase. (509 aa)
	T1EGR9_HELRO	Uncharacterized protein; Belongs to the MT-A70-like family. (261 aa)
	T1EGX4_HELRO	Uncharacterized protein. (220 aa)
	T1EHY6_HELRO	UPF0020 domain-containing protein. (351 aa)
	T1EI70_HELRO	Uncharacterized protein. (200 aa)
	T1EI84_HELRO	Uncharacterized protein. (181 aa)
	T1EJ24_HELRO	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (406 aa)
	T1FSK3_HELRO	Uncharacterized protein. (479 aa)
	T1FSK6_HELRO	THUMP domain-containing protein. (533 aa)
	T1FTA5_HELRO	Uncharacterized protein. (641 aa)
	T1FTF1_HELRO	Methyltransf_21 domain-containing protein. (555 aa)
	T1FTM4_HELRO	Uncharacterized protein. (169 aa)
	T1FTU4_HELRO	Uncharacterized protein. (382 aa)
	T1FUC1_HELRO	Uncharacterized protein. (813 aa)
	T1FUE4_HELRO	UBX domain-containing protein. (639 aa)
	T1FUQ5_HELRO	Methyltransf_25 domain-containing protein. (262 aa)
	T1FVL5_HELRO	U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; Belongs to the methyltransferase superfamily. METTL16/RlmF family. (576 aa)
	T1FW65_HELRO	Uncharacterized protein. (636 aa)
	T1FX47_HELRO	THUMP domain-containing protein. (275 aa)
	T1FXA3_HELRO	Methyltransf_11 domain-containing protein. (291 aa)
	T1FXS3_HELRO	N2227 domain-containing protein. (358 aa)
	T1FXW7_HELRO	MTS domain-containing protein. (215 aa)
	T1FY55_HELRO	Uncharacterized protein. (214 aa)
	T1FY63_HELRO	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (258 aa)
	T1FYX2_HELRO	SAM_MT_TRM5_TYW2 domain-containing protein. (319 aa)
	T1FZD4_HELRO	Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (641 aa)
	T1FZF8_HELRO	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (673 aa)
	T1FZN1_HELRO	Uncharacterized protein; Belongs to the MT-A70-like family. (263 aa)
	T1FZQ0_HELRO	Fe2OG dioxygenase domain-containing protein. (558 aa)
	T1FZU7_HELRO	Uncharacterized protein; Belongs to the MT-A70-like family. (242 aa)
	T1G0J9_HELRO	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (263 aa)
	T1G0P8_HELRO	Uncharacterized protein. (247 aa)
	T1G0T6_HELRO	Methyltransf_11 domain-containing protein. (215 aa)
	T1G117_HELRO	Methyltranfer_dom domain-containing protein. (248 aa)
	T1G172_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (411 aa)
	T1G184_HELRO	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (288 aa)
	T1G1L0_HELRO	Uncharacterized protein. (304 aa)
	T1G1Q9_HELRO	C3H1-type domain-containing protein. (412 aa)
	T1G1Y0_HELRO	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (408 aa)
	T1G2P3_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (377 aa)
	T1G302_HELRO	Uncharacterized protein. (364 aa)
	T1G3L1_HELRO	Uncharacterized protein; Belongs to the MT-A70-like family. (368 aa)
	T1ENR3_HELRO	Uncharacterized protein. (324 aa)
	T1EPG9_HELRO	Methyltransf_11 domain-containing protein. (280 aa)
	T1ESZ0_HELRO	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (725 aa)
	T1EVC7_HELRO	Uncharacterized protein. (306 aa)
	T1EVH1_HELRO	Methyltransf_21 domain-containing protein. (314 aa)
	T1EY05_HELRO	Methyltransf_21 domain-containing protein. (386 aa)
	T1EZ71_HELRO	Uncharacterized protein. (279 aa)
	T1EZ72_HELRO	Uncharacterized protein. (283 aa)
	T1EZ73_HELRO	Uncharacterized protein. (286 aa)
	T1EZK3_HELRO	Methyltranfer_dom domain-containing protein. (143 aa)
	T1EZU6_HELRO	Methyltransf_25 domain-containing protein. (322 aa)
	T1F106_HELRO	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family. (321 aa)
	T1F2K9_HELRO	Uncharacterized protein. (425 aa)
	T1F518_HELRO	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (704 aa)
	T1F569_HELRO	Methyltransf_11 domain-containing protein. (283 aa)
	T1F570_HELRO	Methyltransf_11 domain-containing protein. (303 aa)
	T1F6L1_HELRO	Methyltransf_21 domain-containing protein. (282 aa)
	T1F6N4_HELRO	Methyltransf_21 domain-containing protein. (250 aa)
	T1F702_HELRO	Methyltransf_21 domain-containing protein. (297 aa)
	T1F717_HELRO	Methyltransf_21 domain-containing protein. (264 aa)
	T1F738_HELRO	Uncharacterized protein. (106 aa)
	T1F7M5_HELRO	Uncharacterized protein. (281 aa)
	T1F7M6_HELRO	Uncharacterized protein. (278 aa)
	T1F8E6_HELRO	Uncharacterized protein. (200 aa)
	T1F8E9_HELRO	Uncharacterized protein. (326 aa)
	T1F8Q1_HELRO	Uncharacterized protein. (377 aa)
	T1F8V8_HELRO	Methyltransf_21 domain-containing protein. (234 aa)
	T1F967_HELRO	Uncharacterized protein. (264 aa)
	T1FAJ5_HELRO	Methyltransf_21 domain-containing protein. (322 aa)
	T1FAL9_HELRO	Uncharacterized protein. (277 aa)
	T1FBR8_HELRO	Uncharacterized protein. (197 aa)
	T1FCB3_HELRO	Uncharacterized protein. (297 aa)
	T1FCB5_HELRO	Methyltransf_25 domain-containing protein. (261 aa)
	T1FCB9_HELRO	Uncharacterized protein. (208 aa)
	T1FCC1_HELRO	Methyltransf_25 domain-containing protein. (259 aa)
	T1FCC2_HELRO	Uncharacterized protein. (207 aa)
	T1FD95_HELRO	Uncharacterized protein. (263 aa)
	T1FD96_HELRO	Uncharacterized protein. (260 aa)
	T1FDA2_HELRO	Uncharacterized protein. (166 aa)
	T1FEG0_HELRO	Uncharacterized protein. (253 aa)
	T1FFL2_HELRO	Uncharacterized protein. (300 aa)
	T1FG58_HELRO	Uncharacterized protein. (199 aa)
	T1FG59_HELRO	Uncharacterized protein. (272 aa)
	T1FJP1_HELRO	Uncharacterized protein. (295 aa)
	T1FK69_HELRO	Uncharacterized protein. (263 aa)
	T1FKA6_HELRO	Methyltranfer_dom domain-containing protein. (406 aa)
	T1FKE5_HELRO	Methyltransf_21 domain-containing protein. (281 aa)
	T1FKE6_HELRO	Methyltransf_21 domain-containing protein. (284 aa)
	T1FML4_HELRO	Uncharacterized protein. (282 aa)
	T1FMQ9_HELRO	Uncharacterized protein. (224 aa)
	T1FNH0_HELRO	Uncharacterized protein. (232 aa)
	T1FNJ5_HELRO	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (306 aa)
	T1EGD4_HELRO	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1414 aa)
	T1EFD2_HELRO	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (493 aa)
	T1EF76_HELRO	Bin3-type SAM domain-containing protein. (594 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1ECX9_HELRO	T1EEU9_HELRO	T1ECX9	T1EEU9	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.541
T1ECX9_HELRO	T1FZD4_HELRO	T1ECX9	T1FZD4	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.824
T1EDL3_HELRO	T1F106_HELRO	T1EDL3	T1F106	PABS domain-containing protein.	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family.	0.956
T1EDL3_HELRO	T1FNR4_HELRO	T1EDL3	T1FNR4	PABS domain-containing protein.	PABS domain-containing protein; Belongs to the spermidine/spermine synthase family.	0.955
T1EEM3_HELRO	T1ELK2_HELRO	T1EEM3	T1ELK2	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.471
T1EEM3_HELRO	T1EMG8_HELRO	T1EEM3	T1EMG8	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.471
T1EEM3_HELRO	T1FPG5_HELRO	T1EEM3	T1FPG5	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.444
T1EEM3_HELRO	T1FY55_HELRO	T1EEM3	T1FY55	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.458
T1EEM3_HELRO	T1FZD4_HELRO	T1EEM3	T1FZD4	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.496
T1EEM3_HELRO	T1G2P3_HELRO	T1EEM3	T1G2P3	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.454
T1EEM3_HELRO	T1G6S8_HELRO	T1EEM3	T1G6S8	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.471
T1EEU2_HELRO	T1EI84_HELRO	T1EEU2	T1EI84	Uncharacterized protein.	Uncharacterized protein.	0.550
T1EEU2_HELRO	T1FMQ9_HELRO	T1EEU2	T1FMQ9	Uncharacterized protein.	Uncharacterized protein.	0.411
T1EEU2_HELRO	T1G7U5_HELRO	T1EEU2	T1G7U5	Uncharacterized protein.	Uncharacterized protein.	0.586
T1EEU9_HELRO	T1ECX9_HELRO	T1EEU9	T1ECX9	Uncharacterized protein.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.541
T1EEU9_HELRO	T1EF65_HELRO	T1EEU9	T1EF65	Uncharacterized protein.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.801
T1EEU9_HELRO	T1EFD2_HELRO	T1EEU9	T1EFD2	Uncharacterized protein.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.601
T1EEU9_HELRO	T1EHY6_HELRO	T1EEU9	T1EHY6	Uncharacterized protein.	UPF0020 domain-containing protein.	0.449
T1EEU9_HELRO	T1EJ24_HELRO	T1EEU9	T1EJ24	Uncharacterized protein.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.589
T1EEU9_HELRO	T1ELK2_HELRO	T1EEU9	T1ELK2	Uncharacterized protein.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.717