41 items (Helobdella robusta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	T1FR73_HELRO	Macro domain-containing protein. (504 aa)
	T1G836_HELRO	Poly [ADP-ribose] polymerase. (224 aa)
	T1G7T7_HELRO	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (591 aa)
	T1G4X4_HELRO	Uncharacterized protein. (456 aa)
	T1G481_HELRO	Poly [ADP-ribose] polymerase. (173 aa)
	T1G3Y6_HELRO	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (521 aa)
	T1G282_HELRO	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (516 aa)
	T1G231_HELRO	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (468 aa)
	T1G224_HELRO	Uncharacterized protein. (240 aa)
	T1G1G8_HELRO	YjeF N-terminal domain-containing protein. (282 aa)
	T1G1E3_HELRO	Poly [ADP-ribose] polymerase. (175 aa)
	T1FZR2_HELRO	Uncharacterized protein; Belongs to the 5'-nucleotidase family. (582 aa)
	T1FZ55_HELRO	Uncharacterized protein. (456 aa)
	T1FYW2_HELRO	Poly [ADP-ribose] polymerase. (288 aa)
	T1FWC9_HELRO	Uncharacterized protein. (710 aa)
	T1FV69_HELRO	Uncharacterized protein. (329 aa)
	T1FU72_HELRO	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (794 aa)
	T1FT24_HELRO	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (706 aa)
	T1FRS2_HELRO	Poly [ADP-ribose] polymerase. (1999 aa)
	T1FPF7_HELRO	Uncharacterized protein. (411 aa)
	T1FN31_HELRO	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (367 aa)
	T1FMV0_HELRO	Macro domain-containing protein. (563 aa)
	T1FGS7_HELRO	PHD-type domain-containing protein. (712 aa)
	T1FEY9_HELRO	Uncharacterized protein. (313 aa)
	T1FBF7_HELRO	Uncharacterized protein. (592 aa)
	T1F4C9_HELRO	Uncharacterized protein. (264 aa)
	T1F4C4_HELRO	Uncharacterized protein. (666 aa)
	T1F0D4_HELRO	Uncharacterized protein. (388 aa)
	T1EZ68_HELRO	Poly [ADP-ribose] polymerase. (379 aa)
	T1EYN8_HELRO	5_nucleotid_C domain-containing protein. (268 aa)
	T1EXR0_HELRO	Uncharacterized protein. (479 aa)
	T1EXQ9_HELRO	Uncharacterized protein. (381 aa)
	T1EVX3_HELRO	Uncharacterized protein. (713 aa)
	T1ELP5_HELRO	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (302 aa)
	T1EIC2_HELRO	Macro domain-containing protein. (122 aa)
	T1EIB7_HELRO	Macro domain-containing protein. (124 aa)
	T1EGU1_HELRO	Uncharacterized protein. (151 aa)
	T1EFR0_HELRO	Nicotinamide-nucleotide adenylyltransferase. (333 aa)
	T1EFP6_HELRO	Macro domain-containing protein. (543 aa)
	T1EFI8_HELRO	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (547 aa)
	T1EDM0_HELRO	Poly [ADP-ribose] polymerase. (274 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EFI8_HELRO	T1EFR0_HELRO	T1EFI8	T1EFR0	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Nicotinamide-nucleotide adenylyltransferase.	0.994
T1EFI8_HELRO	T1ELP5_HELRO	T1EFI8	T1ELP5	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.977
T1EFI8_HELRO	T1FBF7_HELRO	T1EFI8	T1FBF7	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein.	0.591
T1EFI8_HELRO	T1FPF7_HELRO	T1EFI8	T1FPF7	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein.	0.591
T1EFI8_HELRO	T1FT24_HELRO	T1EFI8	T1FT24	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.864
T1EFI8_HELRO	T1FZ55_HELRO	T1EFI8	T1FZ55	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein.	0.556
T1EFI8_HELRO	T1FZR2_HELRO	T1EFI8	T1FZR2	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	0.912
T1EFI8_HELRO	T1G3Y6_HELRO	T1EFI8	T1G3Y6	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	0.912
T1EFI8_HELRO	T1G4X4_HELRO	T1EFI8	T1G4X4	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein.	0.967
T1EFR0_HELRO	T1EFI8_HELRO	T1EFR0	T1EFI8	Nicotinamide-nucleotide adenylyltransferase.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.994
T1EFR0_HELRO	T1EGU1_HELRO	T1EFR0	T1EGU1	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein.	0.950
T1EFR0_HELRO	T1ELP5_HELRO	T1EFR0	T1ELP5	Nicotinamide-nucleotide adenylyltransferase.	Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.	0.994
T1EFR0_HELRO	T1EYN8_HELRO	T1EFR0	T1EYN8	Nicotinamide-nucleotide adenylyltransferase.	5_nucleotid_C domain-containing protein.	0.471
T1EFR0_HELRO	T1FBF7_HELRO	T1EFR0	T1FBF7	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein.	0.609
T1EFR0_HELRO	T1FEY9_HELRO	T1EFR0	T1FEY9	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein.	0.900
T1EFR0_HELRO	T1FPF7_HELRO	T1EFR0	T1FPF7	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein.	0.959
T1EFR0_HELRO	T1FT24_HELRO	T1EFR0	T1FT24	Nicotinamide-nucleotide adenylyltransferase.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.994
T1EFR0_HELRO	T1FV69_HELRO	T1EFR0	T1FV69	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein.	0.900
T1EFR0_HELRO	T1FZ55_HELRO	T1EFR0	T1FZ55	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein.	0.960
T1EFR0_HELRO	T1FZR2_HELRO	T1EFR0	T1FZR2	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein; Belongs to the 5'-nucleotidase family.	0.944