25 items (Helobdella robusta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Your Input:
	T1FMV0_HELRO	Macro domain-containing protein. (563 aa)
	T1EDM0_HELRO	Poly [ADP-ribose] polymerase. (274 aa)
	T1EFI8_HELRO	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (547 aa)
	T1EFP6_HELRO	Macro domain-containing protein. (543 aa)
	T1EIB7_HELRO	Macro domain-containing protein. (124 aa)
	T1EIC2_HELRO	Macro domain-containing protein. (122 aa)
	T1EVX3_HELRO	Uncharacterized protein. (713 aa)
	T1EXQ9_HELRO	Uncharacterized protein. (381 aa)
	T1EXR0_HELRO	Uncharacterized protein. (479 aa)
	T1EZ68_HELRO	Poly [ADP-ribose] polymerase. (379 aa)
	T1F0D4_HELRO	Uncharacterized protein. (388 aa)
	T1F4C4_HELRO	Uncharacterized protein. (666 aa)
	T1FGS7_HELRO	PHD-type domain-containing protein. (712 aa)
	T1FN31_HELRO	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. (367 aa)
	T1FR73_HELRO	Macro domain-containing protein. (504 aa)
	T1FRS2_HELRO	Poly [ADP-ribose] polymerase. (1999 aa)
	T1FU72_HELRO	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (794 aa)
	T1FWC9_HELRO	Uncharacterized protein. (710 aa)
	T1FYW2_HELRO	Poly [ADP-ribose] polymerase. (288 aa)
	T1FZ55_HELRO	Uncharacterized protein. (456 aa)
	T1G1E3_HELRO	Poly [ADP-ribose] polymerase. (175 aa)
	T1G1G8_HELRO	YjeF N-terminal domain-containing protein. (282 aa)
	T1G481_HELRO	Poly [ADP-ribose] polymerase. (173 aa)
	T1G4X4_HELRO	Uncharacterized protein. (456 aa)
	T1G836_HELRO	Poly [ADP-ribose] polymerase. (224 aa)

Your Current Organism:

Helobdella robusta

NCBI taxonomy Id: 6412
Other names: H. robusta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1EFI8_HELRO	T1FZ55_HELRO	T1EFI8	T1FZ55	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein.	0.556
T1EFI8_HELRO	T1G4X4_HELRO	T1EFI8	T1G4X4	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein.	0.967
T1EIB7_HELRO	T1FMV0_HELRO	T1EIB7	T1FMV0	Macro domain-containing protein.	Macro domain-containing protein.	0.510
T1EIC2_HELRO	T1FMV0_HELRO	T1EIC2	T1FMV0	Macro domain-containing protein.	Macro domain-containing protein.	0.506
T1EZ68_HELRO	T1G481_HELRO	T1EZ68	T1G481	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.418
T1FMV0_HELRO	T1EIB7_HELRO	T1FMV0	T1EIB7	Macro domain-containing protein.	Macro domain-containing protein.	0.510
T1FMV0_HELRO	T1EIC2_HELRO	T1FMV0	T1EIC2	Macro domain-containing protein.	Macro domain-containing protein.	0.506
T1FN31_HELRO	T1FU72_HELRO	T1FN31	T1FU72	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.	0.865
T1FN31_HELRO	T1G1G8_HELRO	T1FN31	T1G1G8	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	YjeF N-terminal domain-containing protein.	0.865
T1FRS2_HELRO	T1FYW2_HELRO	T1FRS2	T1FYW2	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.561
T1FRS2_HELRO	T1G481_HELRO	T1FRS2	T1G481	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.490
T1FU72_HELRO	T1FN31_HELRO	T1FU72	T1FN31	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family.	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	0.865
T1FYW2_HELRO	T1FRS2_HELRO	T1FYW2	T1FRS2	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.561
T1FYW2_HELRO	T1G481_HELRO	T1FYW2	T1G481	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.561
T1FZ55_HELRO	T1EFI8_HELRO	T1FZ55	T1EFI8	Uncharacterized protein.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.556
T1FZ55_HELRO	T1G4X4_HELRO	T1FZ55	T1G4X4	Uncharacterized protein.	Uncharacterized protein.	0.902
T1G1G8_HELRO	T1FN31_HELRO	T1G1G8	T1FN31	YjeF N-terminal domain-containing protein.	ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.	0.865
T1G481_HELRO	T1EZ68_HELRO	T1G481	T1EZ68	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.418
T1G481_HELRO	T1FRS2_HELRO	T1G481	T1FRS2	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.490
T1G481_HELRO	T1FYW2_HELRO	T1G481	T1FYW2	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.561