STRINGSTRING
T1EDK7_HELRO T1EDK7_HELRO T1EDP1_HELRO T1EDP1_HELRO T1EE08_HELRO T1EE08_HELRO T1EE38_HELRO T1EE38_HELRO T1EE42_HELRO T1EE42_HELRO T1EEC2_HELRO T1EEC2_HELRO T1EEU1_HELRO T1EEU1_HELRO T1EF24_HELRO T1EF24_HELRO T1EFE6_HELRO T1EFE6_HELRO T1EFI5_HELRO T1EFI5_HELRO T1EFL7_HELRO T1EFL7_HELRO T1EFN3_HELRO T1EFN3_HELRO T1EG17_HELRO T1EG17_HELRO T1EG47_HELRO T1EG47_HELRO T1EGK7_HELRO T1EGK7_HELRO T1EGZ8_HELRO T1EGZ8_HELRO T1EH23_HELRO T1EH23_HELRO T1EI10_HELRO T1EI10_HELRO T1EI50_HELRO T1EI50_HELRO T1EIY3_HELRO T1EIY3_HELRO T1EKC8_HELRO T1EKC8_HELRO T1ELE4_HELRO T1ELE4_HELRO T1ELF3_HELRO T1ELF3_HELRO T1ELH8_HELRO T1ELH8_HELRO T1ELY8_HELRO T1ELY8_HELRO T1EM15_HELRO T1EM15_HELRO T1EMJ6_HELRO T1EMJ6_HELRO T1EPK5_HELRO T1EPK5_HELRO T1EVP2_HELRO T1EVP2_HELRO T1EXR8_HELRO T1EXR8_HELRO T1F2G8_HELRO T1F2G8_HELRO T1F3I3_HELRO T1F3I3_HELRO T1F3N5_HELRO T1F3N5_HELRO T1F3N7_HELRO T1F3N7_HELRO T1F4D3_HELRO T1F4D3_HELRO T1F6L9_HELRO T1F6L9_HELRO T1F842_HELRO T1F842_HELRO T1FGC2_HELRO T1FGC2_HELRO T1FKI0_HELRO T1FKI0_HELRO T1FMI4_HELRO T1FMI4_HELRO T1FMK0_HELRO T1FMK0_HELRO T1FMM1_HELRO T1FMM1_HELRO T1FMM8_HELRO T1FMM8_HELRO T1FN78_HELRO T1FN78_HELRO T1FNB2_HELRO T1FNB2_HELRO T1FNK1_HELRO T1FNK1_HELRO T1FNT6_HELRO T1FNT6_HELRO T1FNV9_HELRO T1FNV9_HELRO T1FNX9_HELRO T1FNX9_HELRO T1FP40_HELRO T1FP40_HELRO T1FP42_HELRO T1FP42_HELRO T1FS56_HELRO T1FS56_HELRO T1FT94_HELRO T1FT94_HELRO T1FV43_HELRO T1FV43_HELRO T1FV76_HELRO T1FV76_HELRO T1FWY1_HELRO T1FWY1_HELRO T1FX31_HELRO T1FX31_HELRO T1FX73_HELRO T1FX73_HELRO T1FXP6_HELRO T1FXP6_HELRO T1FZG7_HELRO T1FZG7_HELRO T1FZK3_HELRO T1FZK3_HELRO T1FZL9_HELRO T1FZL9_HELRO T1FZR2_HELRO T1FZR2_HELRO T1FZW5_HELRO T1FZW5_HELRO T1FZX9_HELRO T1FZX9_HELRO T1G0A0_HELRO T1G0A0_HELRO T1G0C4_HELRO T1G0C4_HELRO T1G1B3_HELRO T1G1B3_HELRO T1G1C3_HELRO T1G1C3_HELRO T1G1P9_HELRO T1G1P9_HELRO T1G231_HELRO T1G231_HELRO T1G282_HELRO T1G282_HELRO T1G285_HELRO T1G285_HELRO T1G2P4_HELRO T1G2P4_HELRO T1G2T5_HELRO T1G2T5_HELRO T1G2X1_HELRO T1G2X1_HELRO T1G2Y7_HELRO T1G2Y7_HELRO T1G2Z8_HELRO T1G2Z8_HELRO T1G391_HELRO T1G391_HELRO T1G3A5_HELRO T1G3A5_HELRO T1G3Y6_HELRO T1G3Y6_HELRO T1G4C8_HELRO T1G4C8_HELRO T1G4R4_HELRO T1G4R4_HELRO T1G4U3_HELRO T1G4U3_HELRO T1G539_HELRO T1G539_HELRO T1G5C8_HELRO T1G5C8_HELRO T1G5Y4_HELRO T1G5Y4_HELRO T1G6G7_HELRO T1G6G7_HELRO T1G7H1_HELRO T1G7H1_HELRO T1G7T7_HELRO T1G7T7_HELRO T1G841_HELRO T1G841_HELRO T1G8W5_HELRO T1G8W5_HELRO T1G8W6_HELRO T1G8W6_HELRO T1G9G6_HELRO T1G9G6_HELRO T1G9M4_HELRO T1G9M4_HELRO T1G9U1_HELRO T1G9U1_HELRO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
T1EDK7_HELROAMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (654 aa)
T1EDP1_HELROUncharacterized protein. (603 aa)
T1EE08_HELRORibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (814 aa)
T1EE38_HELRONudix hydrolase domain-containing protein. (308 aa)
T1EE42_HELRO5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (316 aa)
T1EEC2_HELROPhosphodiesterase. (475 aa)
T1EEU1_HELROAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (490 aa)
T1EF24_HELROUncharacterized protein. (1341 aa)
T1EFE6_HELROUncharacterized protein. (622 aa)
T1EFI5_HELROPhosphodiesterase. (600 aa)
T1EFL7_HELROPyruvate kinase; Belongs to the pyruvate kinase family. (579 aa)
T1EFN3_HELROA_deaminase domain-containing protein. (413 aa)
T1EG17_HELROGTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (232 aa)
T1EG47_HELROPhosphodiesterase. (534 aa)
T1EGK7_HELROGuanylate cyclase. (937 aa)
T1EGZ8_HELROMetallophos domain-containing protein. (299 aa)
T1EH23_HELROGuanylate kinase-like domain-containing protein. (119 aa)
T1EI10_HELROUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (244 aa)
T1EI50_HELROA_deaminase domain-containing protein. (251 aa)
T1EIY3_HELROPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (445 aa)
T1EKC8_HELROPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (329 aa)
T1ELE4_HELROUncharacterized protein. (395 aa)
T1ELF3_HELROPribosyltran_N domain-containing protein. (318 aa)
T1ELH8_HELROGuanylate kinase-like domain-containing protein. (202 aa)
T1ELY8_HELROA_deaminase domain-containing protein. (533 aa)
T1EM15_HELROPyruvate kinase; Belongs to the pyruvate kinase family. (503 aa)
T1EMJ6_HELROHD domain-containing protein. (186 aa)
T1EPK5_HELRONUC domain-containing protein. (1446 aa)
T1EVP2_HELRONudix hydrolase domain-containing protein. (144 aa)
T1EXR8_HELROANF_receptor domain-containing protein. (638 aa)
T1F2G8_HELROPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (755 aa)
T1F3I3_HELRODHHA2 domain-containing protein. (296 aa)
T1F3N5_HELROUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (510 aa)
T1F3N7_HELROUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (425 aa)
T1F4D3_HELROUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (372 aa)
T1F6L9_HELROUncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (841 aa)
T1F842_HELROUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (543 aa)
T1FGC2_HELROGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (355 aa)
T1FKI0_HELROUncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (519 aa)
T1FMI4_HELROPfkB domain-containing protein. (407 aa)
T1FMK0_HELROUncharacterized protein. (688 aa)
T1FMM1_HELRORibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (827 aa)
T1FMM8_HELROPhosphodiesterase delta-like protein; Belongs to the PDE6D/unc-119 family. (146 aa)
T1FN78_HELROInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
T1FNB2_HELRONucleoside diphosphate kinase. (151 aa)
T1FNK1_HELROUncharacterized protein; Belongs to the adenylate kinase family. (195 aa)
T1FNT6_HELROInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (514 aa)
T1FNV9_HELROGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (339 aa)
T1FNX9_HELROAIRC domain-containing protein. (420 aa)
T1FP40_HELRONucleoside diphosphate kinase. (141 aa)
T1FP42_HELROUncharacterized protein; Belongs to the phosphohexose mutase family. (560 aa)
T1FS56_HELROGlutamine amidotransferase type-1 domain-containing protein. (1481 aa)
T1FT94_HELROPhosphodiesterase. (893 aa)
T1FV43_HELROATP-grasp domain-containing protein. (1037 aa)
T1FV76_HELROPfkB domain-containing protein. (348 aa)
T1FWY1_HELROUncharacterized protein; Belongs to the adenylate kinase family. (195 aa)
T1FX31_HELROPhosphodiesterase. (500 aa)
T1FX73_HELROGuanylate cyclase. (487 aa)
T1FXP6_HELROUncharacterized protein. (601 aa)
T1FZG7_HELRODM10 domain-containing protein. (387 aa)
T1FZK3_HELROPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (417 aa)
T1FZL9_HELROAdenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily. (169 aa)
T1FZR2_HELROUncharacterized protein; Belongs to the 5'-nucleotidase family. (582 aa)
T1FZW5_HELROUncharacterized protein. (163 aa)
T1FZX9_HELROUncharacterized protein. (352 aa)
T1G0A0_HELROUncharacterized protein. (183 aa)
T1G0C4_HELROPhosphodiesterase. (548 aa)
T1G1B3_HELROPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (322 aa)
T1G1C3_HELROAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (245 aa)
T1G1P9_HELROUncharacterized protein. (468 aa)
T1G231_HELROUncharacterized protein; Belongs to the 5'-nucleotidase family. (468 aa)
T1G282_HELROUncharacterized protein; Belongs to the 5'-nucleotidase family. (516 aa)
T1G285_HELROPribosyltran domain-containing protein. (220 aa)
T1G2P4_HELROPhosphodiesterase. (491 aa)
T1G2T5_HELROPhosphodiesterase. (552 aa)
T1G2X1_HELROUncharacterized protein. (1359 aa)
T1G2Y7_HELROUncharacterized protein. (339 aa)
T1G2Z8_HELROGuanylate cyclase. (578 aa)
T1G391_HELROGuanylate cyclase. (602 aa)
T1G3A5_HELROPyruvate kinase; Belongs to the pyruvate kinase family. (546 aa)
T1G3Y6_HELROUncharacterized protein; Belongs to the 5'-nucleotidase family. (521 aa)
T1G4C8_HELROPhosphodiesterase. (445 aa)
T1G4R4_HELROA_deaminase domain-containing protein. (400 aa)
T1G4U3_HELROGuanylate cyclase. (1064 aa)
T1G539_HELROATPase_AAA_core domain-containing protein. (717 aa)
T1G5C8_HELROPhosphodiesterase. (575 aa)
T1G5Y4_HELROUncharacterized protein. (1009 aa)
T1G6G7_HELROUncharacterized protein. (547 aa)
T1G7H1_HELROPribosyltran domain-containing protein. (185 aa)
T1G7T7_HELROUncharacterized protein; Belongs to the 5'-nucleotidase family. (591 aa)
T1G841_HELROPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (277 aa)
T1G8W5_HELRORibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (756 aa)
T1G8W6_HELROAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (439 aa)
T1G9G6_HELROPDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family. (283 aa)
T1G9M4_HELROMGS domain-containing protein. (594 aa)
T1G9U1_HELROAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (496 aa)
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.