STRINGSTRING
T1ECZ5_HELRO T1ECZ5_HELRO T1EDC7_HELRO T1EDC7_HELRO T1EDF6_HELRO T1EDF6_HELRO T1EDF7_HELRO T1EDF7_HELRO T1EDN4_HELRO T1EDN4_HELRO T1EDV2_HELRO T1EDV2_HELRO T1EDV8_HELRO T1EDV8_HELRO T1EES0_HELRO T1EES0_HELRO T1EET4_HELRO T1EET4_HELRO T1EF05_HELRO T1EF05_HELRO T1EF87_HELRO T1EF87_HELRO T1EFC1_HELRO T1EFC1_HELRO T1EFD8_HELRO T1EFD8_HELRO T1EFL7_HELRO T1EFL7_HELRO T1EFZ3_HELRO T1EFZ3_HELRO T1EG15_HELRO T1EG15_HELRO T1EG43_HELRO T1EG43_HELRO T1EGC3_HELRO T1EGC3_HELRO T1EGH5_HELRO T1EGH5_HELRO T1EJ12_HELRO T1EJ12_HELRO T1ELF3_HELRO T1ELF3_HELRO T1ELL0_HELRO T1ELL0_HELRO T1ELV3_HELRO T1ELV3_HELRO T1EM10_HELRO T1EM10_HELRO T1EM15_HELRO T1EM15_HELRO T1EMC7_HELRO T1EMC7_HELRO T1EMD3_HELRO T1EMD3_HELRO T1EMJ5_HELRO T1EMJ5_HELRO T1EMK4_HELRO T1EMK4_HELRO T1ER33_HELRO T1ER33_HELRO T1ERF8_HELRO T1ERF8_HELRO T1EUC2_HELRO T1EUC2_HELRO T1EZ89_HELRO T1EZ89_HELRO T1F0C2_HELRO T1F0C2_HELRO T1F193_HELRO T1F193_HELRO T1F731_HELRO T1F731_HELRO T1FD06_HELRO T1FD06_HELRO T1FHH1_HELRO T1FHH1_HELRO T1FJD3_HELRO T1FJD3_HELRO T1FM52_HELRO T1FM52_HELRO T1FM91_HELRO T1FM91_HELRO T1FM99_HELRO T1FM99_HELRO T1FMC7_HELRO T1FMC7_HELRO T1FMI8_HELRO T1FMI8_HELRO T1FMN2_HELRO T1FMN2_HELRO T1FMP1_HELRO T1FMP1_HELRO T1FMR4_HELRO T1FMR4_HELRO T1FMS3_HELRO T1FMS3_HELRO T1FMS6_HELRO T1FMS6_HELRO T1FMV2_HELRO T1FMV2_HELRO T1FMW1_HELRO T1FMW1_HELRO T1FMX4_HELRO T1FMX4_HELRO T1FN88_HELRO T1FN88_HELRO T1FN98_HELRO T1FN98_HELRO T1FNM5_HELRO T1FNM5_HELRO T1FNN8_HELRO T1FNN8_HELRO T1FNN9_HELRO T1FNN9_HELRO T1FNT5_HELRO T1FNT5_HELRO T1FNZ8_HELRO T1FNZ8_HELRO T1FP07_HELRO T1FP07_HELRO T1FP48_HELRO T1FP48_HELRO T1FPA9_HELRO T1FPA9_HELRO T1FPC6_HELRO T1FPC6_HELRO T1FPR4_HELRO T1FPR4_HELRO T1FQS0_HELRO T1FQS0_HELRO T1FQX1_HELRO T1FQX1_HELRO T1FRC6_HELRO T1FRC6_HELRO T1FRT6_HELRO T1FRT6_HELRO T1FU61_HELRO T1FU61_HELRO T1FU73_HELRO T1FU73_HELRO T1FUW0_HELRO T1FUW0_HELRO T1FVI7_HELRO T1FVI7_HELRO T1FW26_HELRO T1FW26_HELRO T1FX23_HELRO T1FX23_HELRO T1FXB0_HELRO T1FXB0_HELRO T1FXB9_HELRO T1FXB9_HELRO T1FY37_HELRO T1FY37_HELRO T1FYG3_HELRO T1FYG3_HELRO T1FYJ8_HELRO T1FYJ8_HELRO T1FYU7_HELRO T1FYU7_HELRO T1G061_HELRO T1G061_HELRO T1G187_HELRO T1G187_HELRO T1G1B0_HELRO T1G1B0_HELRO T1G1N8_HELRO T1G1N8_HELRO T1G2H1_HELRO T1G2H1_HELRO T1G2L9_HELRO T1G2L9_HELRO T1G3A5_HELRO T1G3A5_HELRO T1G3Q0_HELRO T1G3Q0_HELRO T1G412_HELRO T1G412_HELRO T1G421_HELRO T1G421_HELRO T1G4I2_HELRO T1G4I2_HELRO T1G565_HELRO T1G565_HELRO T1G726_HELRO T1G726_HELRO T1G792_HELRO T1G792_HELRO T1G880_HELRO T1G880_HELRO T1G8Z4_HELRO T1G8Z4_HELRO T1G902_HELRO T1G902_HELRO T1G944_HELRO T1G944_HELRO T1G995_HELRO T1G995_HELRO T1G997_HELRO T1G997_HELRO T1G9B0_HELRO T1G9B0_HELRO T1G9F3_HELRO T1G9F3_HELRO T1G9W0_HELRO T1G9W0_HELRO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
T1ECZ5_HELRO6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (490 aa)
T1EDC7_HELROAcetyl-coenzyme A synthetase. (678 aa)
T1EDF6_HELROUncharacterized protein. (575 aa)
T1EDF7_HELROSuccinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (448 aa)
T1EDN4_HELROMalate dehydrogenase. (344 aa)
T1EDV2_HELROPALP domain-containing protein. (343 aa)
T1EDV8_HELROPhosphotransferase. (445 aa)
T1EES0_HELROGlucose-6-phosphate isomerase; Belongs to the GPI family. (559 aa)
T1EET4_HELROUncharacterized protein. (404 aa)
T1EF05_HELROMalic enzyme. (602 aa)
T1EF87_HELROUncharacterized protein. (452 aa)
T1EFC1_HELROAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (554 aa)
T1EFD8_HELROMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (657 aa)
T1EFL7_HELROPyruvate kinase; Belongs to the pyruvate kinase family. (579 aa)
T1EFZ3_HELROAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (679 aa)
T1EG15_HELROIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (418 aa)
T1EG43_HELROFBPase domain-containing protein; Belongs to the FBPase class 1 family. (338 aa)
T1EGC3_HELROUncharacterized protein; Belongs to the HAD-like hydrolase superfamily. (306 aa)
T1EGH5_HELROUncharacterized protein; Belongs to the FBPase class 1 family. (353 aa)
T1EJ12_HELROUncharacterized protein. (461 aa)
T1ELF3_HELROPribosyltran_N domain-containing protein. (318 aa)
T1ELL0_HELROPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (333 aa)
T1ELV3_HELROAspartate aminotransferase. (394 aa)
T1EM10_HELROS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (287 aa)
T1EM15_HELROPyruvate kinase; Belongs to the pyruvate kinase family. (503 aa)
T1EMC7_HELROPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
T1EMD3_HELROUncharacterized protein. (453 aa)
T1EMJ5_HELROAminotran_1_2 domain-containing protein. (378 aa)
T1EMK4_HELROUncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
T1ER33_HELROEnolase_C domain-containing protein. (555 aa)
T1ERF8_HELROUncharacterized protein. (527 aa)
T1EUC2_HELROVOC domain-containing protein. (179 aa)
T1EZ89_HELROUncharacterized protein. (700 aa)
T1F0C2_HELROUncharacterized protein; Belongs to the LDH/MDH superfamily. (388 aa)
T1F193_HELROCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (510 aa)
T1F731_HELROGlyceraldehyde-3-phosphate dehydrogenase. (337 aa)
T1FD06_HELROUncharacterized protein. (435 aa)
T1FHH1_HELROACOX domain-containing protein. (477 aa)
T1FJD3_HELROUncharacterized protein. (293 aa)
T1FM52_HELROUncharacterized protein. (436 aa)
T1FM91_HELRODihydrolipoyl dehydrogenase. (506 aa)
T1FM99_HELROAconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (791 aa)
T1FMC7_HELROTriosephosphate isomerase. (252 aa)
T1FMI8_HELROIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (377 aa)
T1FMN2_HELROPALP domain-containing protein. (465 aa)
T1FMP1_HELROFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
T1FMR4_HELROCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (505 aa)
T1FMS3_HELROAminotran_1_2 domain-containing protein. (495 aa)
T1FMS6_HELROGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (166 aa)
T1FMV2_HELROIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (357 aa)
T1FMW1_HELROSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (285 aa)
T1FMX4_HELROGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
T1FN88_HELROAldedh domain-containing protein. (534 aa)
T1FN98_HELROMalate dehydrogenase. (360 aa)
T1FNM5_HELROUncharacterized protein. (546 aa)
T1FNN8_HELROSuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (332 aa)
T1FNN9_HELROMalate dehydrogenase. (335 aa)
T1FNT5_HELROTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (354 aa)
T1FNZ8_HELROGlutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (522 aa)
T1FP07_HELROATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (799 aa)
T1FP48_HELROFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
T1FPA9_HELRO6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (489 aa)
T1FPC6_HELROUncharacterized protein. (514 aa)
T1FPR4_HELROUncharacterized protein. (683 aa)
T1FQS0_HELROPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (393 aa)
T1FQX1_HELROAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (688 aa)
T1FRC6_HELROUncharacterized protein. (921 aa)
T1FRT6_HELROSuccinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (421 aa)
T1FU61_HELROUncharacterized protein. (191 aa)
T1FU73_HELROTransket_pyr domain-containing protein. (1004 aa)
T1FUW0_HELROIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (416 aa)
T1FVI7_HELROUncharacterized protein. (444 aa)
T1FW26_HELROUncharacterized protein. (770 aa)
T1FX23_HELROUncharacterized protein. (743 aa)
T1FXB0_HELROUncharacterized protein. (788 aa)
T1FXB9_HELROUncharacterized protein. (794 aa)
T1FY37_HELROGluconokinase; Belongs to the gluconokinase GntK/GntV family. (179 aa)
T1FYG3_HELROSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (97 aa)
T1FYJ8_HELRO3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (363 aa)
T1FYU7_HELROTransket_pyr domain-containing protein. (626 aa)
T1G061_HELROUncharacterized protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (216 aa)
T1G187_HELROPALP domain-containing protein. (424 aa)
T1G1B0_HELROGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (511 aa)
T1G1N8_HELRORibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
T1G2H1_HELROUncharacterized protein. (220 aa)
T1G2L9_HELROUncharacterized protein. (139 aa)
T1G3A5_HELROPyruvate kinase; Belongs to the pyruvate kinase family. (546 aa)
T1G3Q0_HELROUncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (293 aa)
T1G412_HELROPhosphoglycerate kinase. (415 aa)
T1G421_HELROLipoyl-binding domain-containing protein. (395 aa)
T1G4I2_HELROAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (378 aa)
T1G565_HELROUncharacterized protein. (224 aa)
T1G726_HELRO6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (212 aa)
T1G792_HELROUncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
T1G880_HELROUncharacterized protein. (363 aa)
T1G8Z4_HELROSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
T1G902_HELROPhosphoglycerate kinase. (415 aa)
T1G944_HELROS-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (379 aa)
T1G995_HELROSerine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (448 aa)
T1G997_HELROGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (950 aa)
T1G9B0_HELROCitrate synthase; Belongs to the citrate synthase family. (474 aa)
T1G9F3_HELROB12-binding domain-containing protein. (750 aa)
T1G9W0_HELROPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1139 aa)
Your Current Organism:
Helobdella robusta
NCBI taxonomy Id: 6412
Other names: H. robusta
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