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GCA_002104455_00321 GCA_002104455_00321 rlpA rlpA mrdB mrdB mrdA mrdA rlmH rlmH rsfS rsfS murJ murJ GCA_002104455_00744 GCA_002104455_00744 ftsE ftsE mpl mpl GCA_002104455_01279 GCA_002104455_01279 GCA_002104455_01991 GCA_002104455_01991 nagZ nagZ GCA_002104455_02306 GCA_002104455_02306 GCA_002104455_02307 GCA_002104455_02307 GCA_002104455_02309 GCA_002104455_02309 GCA_002104455_02310 GCA_002104455_02310 murB murB GCA_002104455_02430 GCA_002104455_02430 GCA_002104455_02563 GCA_002104455_02563 GCA_002104455_02564 GCA_002104455_02564 GCA_002104455_02565 GCA_002104455_02565 GCA_002104455_02657 GCA_002104455_02657 GCA_002104455_02845 GCA_002104455_02845 murA murA GCA_002104455_02916 GCA_002104455_02916 GCA_002104455_02917 GCA_002104455_02917 GCA_002104455_02918 GCA_002104455_02918 GCA_002104455_02919 GCA_002104455_02919 GCA_002104455_02920 GCA_002104455_02920 GCA_002104455_02921 GCA_002104455_02921 GCA_002104455_02922 GCA_002104455_02922 GCA_002104455_02923 GCA_002104455_02923 mraZ mraZ rsmH rsmH ftsL ftsL ftsI ftsI murE murE murF murF mraY mraY murD murD ftsW ftsW murG murG murC murC ddl ddl ftsQ ftsQ ftsA ftsA ftsZ ftsZ GCA_002104455_03049 GCA_002104455_03049 mltG mltG pyrC pyrC GCA_002104455_03267 GCA_002104455_03267 serS serS crcB crcB GCA_002104455_03328 GCA_002104455_03328 GCA_002104455_03330 GCA_002104455_03330 GCA_002104455_03332 GCA_002104455_03332 GCA_002104455_03380 GCA_002104455_03380
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCA_002104455_00321Unannotated protein; Belongs to the peptidase S11 family. (395 aa)
rlpAUnannotated protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (294 aa)
mrdBUnannotated protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (371 aa)
mrdAUnannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (659 aa)
rlmHUnannotated protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa)
rsfSUnannotated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (119 aa)
murJUnannotated protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (528 aa)
GCA_002104455_00744Unannotated protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (324 aa)
ftsEUnannotated protein; Part of the ABC transporter FtsEX involved in cellular division. (232 aa)
mplUnannotated protein; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (458 aa)
GCA_002104455_01279Unannotated protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa)
GCA_002104455_01991Unannotated protein. (321 aa)
nagZUnannotated protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (342 aa)
GCA_002104455_02306Unannotated protein; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (84 aa)
GCA_002104455_02307Unannotated protein. (141 aa)
GCA_002104455_02309Unannotated protein. (391 aa)
GCA_002104455_02310Unannotated protein. (250 aa)
murBUnannotated protein; Cell wall formation. (343 aa)
GCA_002104455_02430Unannotated protein. (842 aa)
GCA_002104455_02563Unannotated protein. (339 aa)
GCA_002104455_02564Unannotated protein. (211 aa)
GCA_002104455_02565Unannotated protein. (73 aa)
GCA_002104455_02657Unannotated protein. (1101 aa)
GCA_002104455_02845Unannotated protein. (451 aa)
murAUnannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
GCA_002104455_02916Unannotated protein. (347 aa)
GCA_002104455_02917Unannotated protein; Involved in formation and maintenance of cell shape. (289 aa)
GCA_002104455_02918Unannotated protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (157 aa)
GCA_002104455_02919Unannotated protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (195 aa)
GCA_002104455_02920Unannotated protein. (487 aa)
GCA_002104455_02921Unannotated protein. (1333 aa)
GCA_002104455_02922Unannotated protein. (282 aa)
GCA_002104455_02923Unannotated protein. (482 aa)
mraZUnannotated protein; Belongs to the MraZ family. (152 aa)
rsmHUnannotated protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (313 aa)
ftsLUnannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (104 aa)
ftsIUnannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (584 aa)
murEUnannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (529 aa)
murFUnannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (466 aa)
mraYUnannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murDUnannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (464 aa)
ftsWUnannotated protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (420 aa)
murGUnannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (368 aa)
murCUnannotated protein; Cell wall formation; Belongs to the MurCDEF family. (490 aa)
ddlUnannotated protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (311 aa)
ftsQUnannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (259 aa)
ftsAUnannotated protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (411 aa)
ftsZUnannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (389 aa)
GCA_002104455_03049Unannotated protein. (258 aa)
mltGUnannotated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (345 aa)
pyrCUnannotated protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (342 aa)
GCA_002104455_03267Unannotated protein. (276 aa)
serSUnannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa)
crcBUnannotated protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (133 aa)
GCA_002104455_03328Unannotated protein. (451 aa)
GCA_002104455_03330Unannotated protein. (839 aa)
GCA_002104455_03332Unannotated protein; Belongs to the AlaDH/PNT family. (373 aa)
GCA_002104455_03380Unannotated protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (787 aa)
Your Current Organism:
Colwellia chukchiensis
NCBI taxonomy Id: 641665
Other names: C. chukchiensis, CGMCC 1.9127, Colwellia chukchiensis Yu et al. 2011, Colwellia sp. BCw111, DSM 22576, LMG 25329, LMG:25329, strain BCw111
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