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Daes_0149 Daes_0149 panB panB Daes_0391 Daes_0391 coaX coaX Daes_0531 Daes_0531 Daes_0720 Daes_0720 Daes_0721 Daes_0721 bioB bioB bioD bioD Daes_0961 Daes_0961 Daes_0962 Daes_0962 Daes_0963 Daes_0963 Daes_0964 Daes_0964 panD panD panC panC nadK nadK Daes_1716 Daes_1716 Daes_1717 Daes_1717 Daes_1718 Daes_1718 Daes_1719 Daes_1719 Daes_2031 Daes_2031 Daes_2033 Daes_2033 nadK-2 nadK-2 Daes_2282 Daes_2282 nadD nadD cobB cobB Daes_3097 Daes_3097 Daes_3099 Daes_3099 nadE nadE Daes_3341 Daes_3341
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Daes_0149PFAM: Silent information regulator protein Sir2; KEGG: nam:NAMH_0804 NAD-dependent deacetylase. (249 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (296 aa)
Daes_0391PFAM: Methyltransferase type 11; KEGG: bmq:BMQ_3659 putative methyltransferase. (212 aa)
coaXTranscriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (256 aa)
Daes_0531PFAM: Methyltransferase type 11; KEGG: sfu:Sfum_0240 methyltransferase type 11. (207 aa)
Daes_0720PFAM: CinA domain protein; KEGG: alv:Alvin_1664 CinA domain protein; Belongs to the CinA family. (161 aa)
Daes_0721Hypothetical protein; KEGG: syw:SYNW1883 SMR family transporter PecM. (140 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (341 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (198 aa)
Daes_0961PFAM: aminotransferase class-III; KEGG: dap:Dacet_1109 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)
Daes_09628-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (377 aa)
Daes_0963KEGG: dsa:Desal_1448 hypothetical protein. (200 aa)
Daes_0964PFAM: Methyltransferase type 11; KEGG: dsa:Desal_1449 methyltransferase type 11. (256 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (125 aa)
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (255 aa)
Daes_1716Magnesium transporter; Acts as a magnesium transporter. (443 aa)
Daes_1717TIGRFAM: nicotinate-nucleotide pyrophosphorylase; KEGG: dsa:Desal_1976 nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (289 aa)
Daes_1718Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (345 aa)
Daes_1719L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (533 aa)
Daes_2031PFAM: peptidase M29 aminopeptidase II; KEGG: dsa:Desal_1300 peptidase M29 aminopeptidase II. (399 aa)
Daes_2033PFAM: isochorismatase hydrolase; KEGG: bmq:BMQ_pBM70137 acetyltransferase, GNAT family. (177 aa)
nadK-2ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (293 aa)
Daes_2282PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: dvm:DvMF_2358 fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (492 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (218 aa)
cobBPFAM: Silent information regulator protein Sir2; KEGG: sfu:Sfum_3557 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. (243 aa)
Daes_3097KEGG: rpi:Rpic_3189 hypothetical protein. (230 aa)
Daes_3099PFAM: Methyltransferase type 11; KEGG: dvl:Dvul_1584 methyltransferase type 11. (243 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (556 aa)
Daes_3341Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (405 aa)
Your Current Organism:
Pseudodesulfovibrio aespoeensis
NCBI taxonomy Id: 643562
Other names: Desulfovibrio aespoeensis Aspo-2, Desulfovibrio aespoeensis DSM 10631, P. aespoeensis Aspo-2, Pseudodesulfovibrio aespoeensis Aspo-2, Pseudodesulfovibrio aespoeensis DSM 10631
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