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Slip_0446 Slip_0446 mltG mltG murJ murJ Slip_0159 Slip_0159 Slip_0158 Slip_0158 glmU glmU murI murI murE murE murF murF mraY mraY murD murD murG murG uppP uppP Slip_1012 Slip_1012 murA murA murC murC Slip_2381 Slip_2381 murA-3 murA-3 murA-2 murA-2 Slip_0908 Slip_0908 murB murB Slip_1100 Slip_1100 ddl ddl Slip_1372 Slip_1372 Slip_1396 Slip_1396 murJ-2 murJ-2 Slip_1678 Slip_1678 Slip_1775 Slip_1775 Slip_0763 Slip_0763 Slip_0721 Slip_0721 Slip_0524 Slip_0524 Slip_0516 Slip_0516
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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Slip_0446KEGG: swo:Swol_0594 hypothetical protein; SPTR: Q0AZD1 Putative uncharacterized protein; PFAM: Glycosyl transferase family 4. (278 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (340 aa)
murJIntegral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (528 aa)
Slip_0159Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: swo:Swol_0125 putative transcriptional regulator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Q0B0M4 Putative transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. (353 aa)
Slip_0158Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: swo:Swol_0124 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Q0B0M5 Glycosyl transferase, family 4; PFAM: Glycosyl transferase family 4. (354 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (462 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (273 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (493 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/ D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (459 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (324 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (456 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (372 aa)
uppPUndecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (259 aa)
Slip_1012Serine-type D-Ala-D-Ala carboxypeptidase; COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967:IPR018044:IPR012338:IPR015956; KEGG: swo:Swol_0909 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Q0AYH9 Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family. (401 aa)
murAUDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (461 aa)
Slip_2381COGs: COG1847 RNA-binding protein; InterPro IPR001374:IPR004044; KEGG: swo:Swol_2573 single-stranded nucleic acid binding R3H; PFAM: single-stranded nucleic acid binding R3H domain protein; KH type 2 domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; SPTR: Q0ATU4 Single-stranded nucleic acid binding R3H; PFAM: R3H domain. (209 aa)
murA-3UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (415 aa)
murA-2UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (434 aa)
Slip_0908Conserved hypothetical protein; COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR009019:IPR004088; KEGG: ckr:CKR_1299 hypothetical protein; SPTR: B9E1H5 Putative uncharacterized protein; Belongs to the UPF0109 family. (76 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (299 aa)
Slip_1100Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264:IPR001460:IPR011816:IPR012338; KEGG: drm:Dred_1803 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; SPTR: A4J5H5 Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. (697 aa)
ddlD-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (314 aa)
Slip_1372Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR012338:IPR001264:IPR001460:IPR011816; KEGG: swo:Swol_0921 penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; SPTR: Q0AYG7 Penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein 1B; penicillin-binding protein, 1A family. (646 aa)
Slip_1396Serine-type D-Ala-D-Ala carboxypeptidase; COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterProIPR012338:IPR015956:IPR001967:IPR012907:IPR 018044; KEGG: chy:CHY_2101 D-alanyl-D-alanine carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Q3AAB4 D-alanyl-D-alanine carboxypeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family. (427 aa)
murJ-2Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (523 aa)
Slip_1678COGs: COG5632 N-acetylmuramoyl-L-alanine amidase; InterPro IPR001119:IPR002502; KEGG: bbe:BBR47_50840 putative N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; S-layer domain protein; SMART: N-acetylmuramoyl-L-alanine amidase family 2; SPTR: C0Z5F5 Putative N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; S-layer homology domain. (249 aa)
Slip_1775Glycosidase-related protein; COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: swo:Swol_1919 glycosylase-like protein; PFAM: glycosidase PH1107-related; SPTR: Q0AVN8 Glycosylase-like protein; PFAM: Domain of unknown function (DUF377); TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type. (1200 aa)
Slip_0763Glycosidase-related protein; COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: swo:Swol_1919 glycosylase-like protein; PFAM: glycosidase PH1107-related; SPTR: Q0AVN8 Glycosylase-like protein; PFAM: Domain of unknown function (DUF377). (1211 aa)
Slip_0721Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR012338:IPR001264:IPR001460:IPR011816; KEGG: swo:Swol_1109 peptidoglycan glycosyltransferase; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; SPTR: Q0AXY5 Peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; penicillin-binding protei [...] (784 aa)
Slip_0524Serine-type D-Ala-D-Ala carboxypeptidase; COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterProIPR012338:IPR015956:IPR001967:IPR012907:IPR 018044; KEGG: swo:Swol_0612 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Q0AZB3 Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family. (381 aa)
Slip_0516Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: tdn:Suden_0836 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Q30SB7 Diguanylate cyclase (GGDEF domain); TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (402 aa)
Your Current Organism:
Syntrophothermus lipocalidus
NCBI taxonomy Id: 643648
Other names: S. lipocalidus DSM 12680, Syntrophothermus lipocalidus DSM 12680, Syntrophothermus lipocalidus TGB-C1, Syntrophothermus lipocalidus str. DSM 12680, Syntrophothermus lipocalidus strain DSM 12680
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