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ADC70118.1 ADC70118.1 hypA hypA cdhC cdhC ADC70380.1 ADC70380.1 ADC70315.1 ADC70315.1 ADC70119.1 ADC70119.1 cdhA cdhA cdhC-2 cdhC-2 ADC68907.1 ADC68907.1 ADC68974.1 ADC68974.1 ADC69015.1 ADC69015.1 ADC69506.1 ADC69506.1 ADC69230.1 ADC69230.1 ADC69628.1 ADC69628.1 ADC69629.1 ADC69629.1 ADC69631.1 ADC69631.1 ADC69677.1 ADC69677.1 cbiX cbiX
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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Your Input:
ADC70118.1KEGG: mja:MJ0728 carbon monoxide dehydrogenase, catalytic subunit (CooS); TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane. (624 aa)
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (125 aa)
cdhCCO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. (470 aa)
ADC70380.1TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: mja:MJ0442 hydrogenase expression/formation protein (HypB). (223 aa)
ADC70315.1PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; nickel-dependent hydrogenase large subunit; KEGG: mja:MJ1027 formate hydrogenlyase, subunit 5. (374 aa)
ADC70119.1PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ0727 coenzyme F420-reducing hydrogenase, alpha subunit. (298 aa)
cdhACO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (773 aa)
cdhC-2CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. (757 aa)
ADC68907.1PFAM: nickel-dependent hydrogenase large subunit; KEGG: mvu:Metvu_0716 nickel-dependent hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (472 aa)
ADC68974.1PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; nickel-dependent hydrogenase large subunit; KEGG: mja:MJ0515 carbon monoxide dehydrogenase, hydrogenase subunit CooH (CooH); Belongs to the complex I 49 kDa subunit family. (377 aa)
ADC69015.1Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (141 aa)
ADC69506.1PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ1192m methylviologen-reducing hydrogenase, alpha subunit. (418 aa)
ADC69230.1PFAM: protein of unknown function DUF111; KEGG: mja:MJ1387 hypothetical protein; Belongs to the LarC family. (378 aa)
ADC69628.1TIGRFAM: coenzyme F420 hydrogenase, subunit beta; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: mja:MJ0032 coenzyme F420-reducing hydrogenase subunit beta. (282 aa)
ADC69629.1TIGRFAM: coenzyme F420 hydrogenase, subunit gamma; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0031 coenzyme F420-reducing hydrogenase, gamma subunit. (227 aa)
ADC69631.1Contains selenocysteine; TIGRFAM: coenzyme F420 hydrogenase, subunit alpha; PFAM: nickel-dependent hydrogenase large subunit; KEGG: mja:MJ0029 coenzyme F420-reducing hydrogenase, alpha subunit, selenocysteine-containing; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (410 aa)
ADC69677.1PFAM: cobalamin synthesis protein P47K; KEGG: mja:MJ0120 urease accessory protein (UreG). (233 aa)
cbiXCobalamin (vitamin B12) biosynthesis CbiX protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (147 aa)
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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