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sucC sucC cdhC-2 cdhC-2 ADC68836.1 ADC68836.1 ADC68958.1 ADC68958.1 ADC69002.1 ADC69002.1 ADC69003.1 ADC69003.1 ADC69008.1 ADC69008.1 ADC69049.1 ADC69049.1 ADC69109.1 ADC69109.1 ADC69166.1 ADC69166.1 ADC69167.1 ADC69167.1 ADC69168.1 ADC69168.1 ADC69169.1 ADC69169.1 ADC69170.1 ADC69170.1 ADC69171.1 ADC69171.1 sucD sucD ADC69426.1 ADC69426.1 ADC69538.1 ADC69538.1 ADC69539.1 ADC69539.1 ADC69627.1 ADC69627.1 cdhE cdhE cdhD cdhD ADC69710.1 ADC69710.1 ADC70118.1 ADC70118.1 ADC70432.1 ADC70432.1
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (364 aa)
cdhC-2CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. (757 aa)
ADC68836.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0146 2-ketoglutarate ferredoxin oxidoreductase, subunit delta (KorD). (66 aa)
ADC68958.1PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mja:MJ0276 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. (366 aa)
ADC69002.1TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: mja:MJ0536 2-oxoglutarate ferredoxin oxidoreductase subunit gamma. (180 aa)
ADC69003.1PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mja:MJ0537 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (270 aa)
ADC69008.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (765 aa)
ADC69049.1KEGG: mja:MJ1294 fumarate hydratase; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (282 aa)
ADC69109.1TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; ferredoxin; KEGG: mja:MJ0092 succinate dehydrogenase/fumarate reductase iron-sulfur subunit. (489 aa)
ADC69166.1TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: mja:MJ0269 pyruvate ferredoxin oxidoreductase subunit gamma. (179 aa)
ADC69167.1TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0268 pyruvate ferredoxin oxidoreductase, subunit delta (PorD). (86 aa)
ADC69168.1PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mja:MJ0267 pyruvate ferredoxin oxidoreductase, subunit alpha (PorA). (386 aa)
ADC69169.1PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mja:MJ0266 pyruvate ferredoxin oxidoreductase subunit beta. (295 aa)
ADC69170.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0265 carbon monoxide dehydrogenase, iron sulfur subunit CooF-1 (cooF2). (164 aa)
ADC69171.1PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mja:MJ0264 carbon monoxide dehydrogenase, iron sulfur subunit CooF-1 (cooF1). (141 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (288 aa)
ADC69426.1PFAM: Beta-ketoacyl synthase; KEGG: mja:MJ1549 acetyl-CoA acetyltransferase. (392 aa)
ADC69538.1TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: mja:MJ1229 pyruvate carboxylase subunit A. (501 aa)
ADC69539.1TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; biotin/lipoyl attachment domain-containing protein; KEGG: mja:MJ1231 pyruvate carboxylase subunit B. (567 aa)
ADC69627.1PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: mfe:Mefer_1238 fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (540 aa)
cdhECO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). (488 aa)
cdhDCO dehydrogenase/acetyl-CoA synthase, delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. (406 aa)
ADC69710.1KEGG: mja:MJ0617 tartrate dehydratse, subunit beta (TtdB); TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region. (218 aa)
ADC70118.1KEGG: mja:MJ0728 carbon monoxide dehydrogenase, catalytic subunit (CooS); TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane. (624 aa)
ADC70432.1PFAM: Lactate/malate dehydrogenase; KEGG: mja:MJ0490 malate dehydrogenase; Belongs to the LDH/MDH superfamily. (313 aa)
Your Current Organism:
Methanocaldococcus sp. FS40622
NCBI taxonomy Id: 644281
Other names: M. sp. FS406-22, Methanocaldococcus sp. FS406-22
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