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hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (125 aa) | ||||
hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (291 aa) | ||||
Deba_0092 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004839:IPR015424:IPR004838:IPR001176:IPR 015421; KEGG: dol:Dole_1584 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A8ZZY8 Aminotransferase class I and II; PFAM: Aminotransferase class I and II. (395 aa) | ||||
trpB | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (451 aa) | ||||
Deba_0478 | COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099:IPR016040; KEGG: dal:Dalk_1765 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: B8FFQ7 Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase. (259 aa) | ||||
Deba_0479 | COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR008242:IPR 002701:IPR018528; KEGG: pca:Pcar_1887 chorismate mutase-P and prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Q1K0T9 Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II. (410 aa) | ||||
Deba_0480 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR013785:IPR006268; KEGG: sat:SYN_01940 phospho-2-dehydro-3-deoxyheptanoate aldolase; PFAM: DAHP synthetase I/KDSA; SPTR: Q2LUE1 Phospho-2-dehydro-3-deoxyheptanoate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (296 aa) | ||||
Deba_0494 | KEGG: cpb:Cphamn1_2546 hypothetical protein; SPTR: B3EQE2 Putative uncharacterized protein; PFAM: Putative Phosphatase. (245 aa) | ||||
Deba_0561 | KEGG: ppg:PputGB1_3052 nonspecific acid phosphatase; SPTR: B0KGE3 Nonspecific acid phosphatase. (330 aa) | ||||
Deba_0572 | Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: mrd:Mrad2831_2432 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B1LZ06 Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (374 aa) | ||||
trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa) | ||||
trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (408 aa) | ||||
trpF | N-(5'phosphoribosyl)anthranilate isomerase (PRAI); COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR013785:IPR011060:IPR001240; KEGG: gme:Gmet_2492 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); SPTR: Q39SQ9 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. (205 aa) | ||||
trpC | COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013785:IPR011060:IPR013798:IPR001468; KEGG: afw:Anae109_0373 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: A7H792 Indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (265 aa) | ||||
trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (345 aa) | ||||
Deba_0721 | COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterProIPR015421:IPR015422:IPR015424:IPR000192:IPR 020578; KEGG: tye:THEYE_A0936 soluble hydrogenase 42 kDa subunit; PFAM: aminotransferase class V; SPTR: A3EWA6 Aminotransferase, class V; PFAM: Aminotransferase class-V. (380 aa) | ||||
Deba_0722 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR016040:IPR006139:IPR006140; KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: B8FLC2 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase. (316 aa) | ||||
asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa) | ||||
argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (345 aa) | ||||
Deba_0944 | COGs: COG0527 Aspartokinase; InterProIPR001057:IPR001048:IPR002912:IPR018042:IPR 001341:IPR005260; KEGG: pca:Pcar_1006 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Q3A5V0 Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (414 aa) | ||||
mqnA | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (276 aa) | ||||
Deba_1163 | COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (410 aa) | ||||
hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa) | ||||
Deba_1359 | COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR000634:IPR004450; KEGG: dal:Dalk_4397 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: B8FNA7 Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (500 aa) | ||||
Deba_1382 | COGs: COG0460 Homoserine dehydrogenase; InterProIPR005106:IPR001342:IPR002912:IPR019811:IPR 016204:IPR016040; KEGG: gsu:GSU1693 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Q74CI0 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (435 aa) | ||||
hisB | COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807:IPR020565:IPR020568; KEGG: gyc:GYMC61_3155 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: C9RV81 Imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase. (195 aa) | ||||
hisA | COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062:IPR013785:IPR006063:IPR011060; KEGG: avn:Avin_04620 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: Q0EX95 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: H [...] (242 aa) | ||||
hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa) | ||||
hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (215 aa) | ||||
Deba_1734 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR015421:IPR015422:IPR 001176:IPR004838; KEGG: dal:Dalk_0567 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: B8FHI5 Aminotransferase class I and II; PFAM: Aminotransferase class I and II. (392 aa) | ||||
aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (176 aa) | ||||
Deba_1871 | TRASH domain protein; InterPro IPR011017; KEGG: sfu:Sfum_0052 TRASH domain-containing protein; SMART: TRASH domain protein; SPTR: A0LEA3 TRASH domain protein. (95 aa) | ||||
dapL | LL-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (388 aa) | ||||
Deba_1874 | 5-carboxymethyl-2-hydroxymuconateDelta- isomerase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529:IPR011234; KEGG: pmo:Pmob_0980 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: A9BJV9 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family. (264 aa) | ||||
dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa) | ||||
dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa) | ||||
dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (301 aa) | ||||
lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) | ||||
Deba_1879 | Fibronectin type III domain protein; InterPro IPR003961:IPR008957; KEGG: sus:Acid_1064 fibronectin, type III domain-containing protein; PFAM: Fibronectin type III domain protein; SPTR: Q02A64 Fibronectin, type III domain protein; PFAM: Fibronectin type III domain. (355 aa) | ||||
argH | COGs: COG0165 Argininosuccinate lyase; InterProIPR020557:IPR003031:IPR000362:IPR008948:IPR 009049; KEGG: dma:DMR_26520 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C4XUC1 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase. (469 aa) | ||||
argG | COGs: COG0137 Argininosuccinate synthase; InterPro IPR018223:IPR001518:IPR014729; KEGG: dal:Dalk_0409 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: B8FH30 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (404 aa) | ||||
Deba_1882 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (309 aa) | ||||
argD | COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterProIPR005814:IPR015424:IPR015422:IPR015421:IPR 004636; KEGG: sfu:Sfum_0063 acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: A0LEB4 Acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (398 aa) | ||||
argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa) | ||||
hslU | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (457 aa) | ||||
hslV | 20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (180 aa) | ||||
xerC-2 | Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (325 aa) | ||||
Deba_1888 | Methyltransferase type 12; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013217; KEGG: npu:Npun_F0952 methyltransferase type 11; PFAM: Methyltransferase type 12; SPTR: B2IUB2 Methyltransferase type 11; PFAM: Methyltransferase domain. (226 aa) | ||||
Deba_1893 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR013785:IPR006268; KEGG: tte:TTE1013 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; SPTR: Q8R5T1 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase. (343 aa) | ||||
Deba_1979 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004838:IPR001176:IPR004839:IPR015424:IPR 015421; KEGG: rsd:TGRD_536 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: B1H0I7 Aspartate aminotransferase; PFAM: Aminotransferase class I and II. (397 aa) | ||||
Deba_2156 | Hypothetical protein; KEGG: mex:Mext_1994 beta-lactamase domain-containing protein; SPTR: A9W487 Beta-lactamase domain protein. (161 aa) | ||||
Deba_2497 | COGs: COG2021 Homoserine acetyltransferase; InterPro IPR006296:IPR000073:IPR008220; KEGG: rca:Rcas_2039 homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; PRIAM: Homoserine O-acetyltransferase; SPTR: A7NKV7 Homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; TIGRFAM: homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (382 aa) | ||||
hisC | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR005861:IPR001917:IPR015421:IPR015422:IPR 015424:IPR004839; KEGG: sfu:Sfum_2116 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A0LK47 Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (371 aa) | ||||
Deba_2864 | GCN5-related N-acetyltransferase; COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182:IPR016181; KEGG: sfu:Sfum_1203 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: A0LHJ4 N-acetylglutamate synthase; PFAM: Acetyltransferase (GNAT) family. (150 aa) | ||||
argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (416 aa) | ||||
Deba_3080 | COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterProIPR006426:IPR000583:IPR001962:IPR017932:IPR 014729; KEGG: rrs:RoseRS_4439 asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: A5V1L8 Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (625 aa) | ||||
Deba_3185 | Glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR006221:IPR000991:IPR017926:IPR006220:IPR 011702:IPR001317; KEGG: dol:Dole_1098 glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; SPTR: A8ZX49 Glutamine amidotransferase of anthranilate synthase; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (197 aa) | ||||
Deba_3186 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterProIPR005802:IPR005801:IPR001544:IPR006805:IPR 015890:IPR019999; KEGG: dat:HRM2_08090 PabB; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; aminotransferase class IV; SPTR: C0QJR9 PabB; TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Aminotransferase class IV; Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. (754 aa) | ||||
Deba_3213 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR005801:IPR006805:IPR015890:IPR019999; KEGG: sth:STH1407 anthranilate synthetase component I; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; PRIAM: Anthranilate synthase; SPTR: Q67PK1 Anthranilate synthetase component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme. (462 aa) | ||||
Deba_3214 | Glutamine amidotransferase of anthranilate synthase; COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR006221:IPR000991:IPR017926:IPR006220:IPR 011702:IPR001317; KEGG: net:Neut_0135 anthranilate synthase component II; PFAM: glutamine amidotransferase class-I; SPTR: Q0AJP8 Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. (194 aa) | ||||
Deba_3215 | Phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218:IPR013785; KEGG: adg:Adeg_1912 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: C9R9L3 Phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; phospho-2-dehydro-3-deoxyheptonate aldolase. (346 aa) | ||||
aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (421 aa) | ||||
Deba_3217 | Shikimate dehydrogenase substrate binding domain protein; COGs: COG0169 Shikimate 5-dehydrogenase; InterPro IPR016040:IPR013708:IPR006151; KEGG: dat:HRM2_30830 AroE2; PFAM: Shikimate dehydrogenase substrate binding domain protein; Shikimate/quinate 5-dehydrogenase; SPTR: C0QKS6 AroE2; PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase. (276 aa) | ||||
aroK-2 | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (520 aa) | ||||
aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (356 aa) | ||||
aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |