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Deba_3197 Deba_3197 Deba_0003 Deba_0003 Deba_0015 Deba_0015 gltX gltX Deba_0138 Deba_0138 Deba_0149 Deba_0149 purE purE birA birA Deba_0210 Deba_0210 Deba_0211 Deba_0211 purL purL Deba_0230 Deba_0230 metG metG rtcB rtcB atpF-2 atpF-2 atpH atpH atpA atpA atpG atpG atpD atpD atpC atpC tyrS tyrS Deba_0298 Deba_0298 Deba_0305 Deba_0305 asnS asnS Deba_0382 Deba_0382 Deba_0386 Deba_0386 ileS ileS Deba_0425 Deba_0425 Deba_0465 Deba_0465 Deba_0506 Deba_0506 cysS cysS Deba_0542 Deba_0542 Deba_0581 Deba_0581 Deba_0585 Deba_0585 bioD bioD Deba_0682 Deba_0682 tilS tilS Deba_0770 Deba_0770 Deba_0805 Deba_0805 Deba_0817 Deba_0817 thrS thrS pheS pheS pheT pheT Deba_0844 Deba_0844 gatB gatB Deba_0853 Deba_0853 Deba_0860 Deba_0860 hisS hisS aspS aspS Deba_0880 Deba_0880 Deba_0881 Deba_0881 Deba_0915 Deba_0915 panC panC cbiA cbiA Deba_1017 Deba_1017 Deba_1111 Deba_1111 Deba_1133 Deba_1133 alaS alaS Deba_1142 Deba_1142 Deba_1146 Deba_1146 nadE nadE sucD sucD sucC sucC Deba_1219 Deba_1219 proS proS purM purM Deba_1278 Deba_1278 Deba_1289 Deba_1289 purA purA purC purC Deba_1398 Deba_1398 Deba_1399 Deba_1399 leuS leuS Deba_1444 Deba_1444 atpA-2 atpA-2 atpB atpB Deba_1448 Deba_1448 Deba_1450 Deba_1450 Deba_1464 Deba_1464 pyrG pyrG Deba_1481 Deba_1481 Deba_1493 Deba_1493 Deba_1622 Deba_1622 Deba_1628 Deba_1628 Deba_1674 Deba_1674 Deba_1699 Deba_1699 Deba_1780 Deba_1780 argG argG Deba_1904 Deba_1904 gatC gatC gatA gatA glyS glyS glyQ glyQ Deba_1988 Deba_1988 valS valS trpS trpS queC queC Deba_2081 Deba_2081 lysS lysS acsA acsA Deba_2138 Deba_2138 Deba_2144 Deba_2144 Deba_2173 Deba_2173 fhs fhs guaA guaA Deba_2446 Deba_2446 cbiA-2 cbiA-2 Deba_2469 Deba_2469 Deba_2503 Deba_2503 Deba_2516 Deba_2516 Deba_2517 Deba_2517 Deba_2519 Deba_2519 Deba_2520 Deba_2520 Deba_2565 Deba_2565 Deba_2681 Deba_2681 ligA ligA Deba_2719 Deba_2719 atpB-2 atpB-2 atpE atpE Deba_2741 Deba_2741 Deba_2748 Deba_2748 Deba_2756 Deba_2756 Deba_2772 Deba_2772 murE murE murF murF murD murD murC murC argS argS Deba_3025 Deba_3025 Deba_3039 Deba_3039 Deba_3051 Deba_3051 Deba_3080 Deba_3080 Deba_3093 Deba_3093 Deba_3094 Deba_3094 carB carB carA carA Deba_3171 Deba_3171 acsA-2 acsA-2 glnS glnS Deba_3253 Deba_3253 Deba_3254 Deba_3254 Deba_3255 Deba_3255 Deba_3256 Deba_3256 serS serS
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Deba_3197COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dol:Dole_1473 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZZC4 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (537 aa)
Deba_0003COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_3725 acyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FLQ8 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (548 aa)
Deba_0015AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873:IPR020845; KEGG: ade:Adeh_2886 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2IDJ9 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (596 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (471 aa)
Deba_0138COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dol:Dole_0337 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZSY3 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (581 aa)
Deba_0149COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: chy:CHY_0845 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q3ADT8 Long-chain-fatty-acid--CoA ligase; PFAM: AMP-binding enzyme. (490 aa)
purEPhosphoribosylamine/glycine ligase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family. (589 aa)
birAbiotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (333 aa)
Deba_0210COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011095:IPR011761:IPR013816; KEGG: sfu:Sfum_0713 D-alanine--D-alanine ligase domain-containing protein; PFAM: D-alanine--D-alanine ligase domain protein; SPTR: A0LG59 D-alanine--D-alanine ligase domain protein; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. (340 aa)
Deba_0211COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011095:IPR011761:IPR013816; KEGG: sfu:Sfum_0712 D-alanine--D-alanine ligase domain-containing protein; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: A0LG58 D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; TIGRFAM: D-alanine--D-alanine ligase. (328 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (1001 aa)
Deba_0230COGs: COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase glutamine amidotransferase domain; InterPro IPR010075; KEGG: dol:Dole_0483 phosphoribosylformylglycinamidine synthase; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: A8ZTM9 Phosphoribosylformylglycinamidine synthase. (277 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (656 aa)
rtcBProtein of unknown function UPF0027; COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: pca:Pcar_0019 hypothetical protein; PFAM: protein of unknown function UPF0027; SPTR: Q3A8L0 Putative uncharacterized protein; PFAM: Uncharacterized protein family UPF0027; Belongs to the RtcB family. (480 aa)
atpF-2ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (221 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (183 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (504 aa)
atpGATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (469 aa)
atpCATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (137 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (410 aa)
Deba_0298COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_4880 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FDC5 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (594 aa)
Deba_0305COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR020845; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (546 aa)
asnSCOGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; InterProIPR004365:IPR004364:IPR016027:IPR012340:IPR 002312:IPR004522:IPR006195; KEGG: dvu:DVU0007 asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Asparagine--tRNA ligase; SPTR: C5TZ48 Asparaginyl-tRNA synthetase; TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase. (454 aa)
Deba_0382RimK domain protein ATP-grasp; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR013651:IPR011761; KEGG: dba:Dbac_2700 RimK domain protein ATP-grasp; PFAM: RimK domain protein ATP-grasp; SPTR: C7LTL0 RimK domain protein ATP-grasp; PFAM: RimK-like ATP-grasp domain. (298 aa)
Deba_0386COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_0599 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FHL6 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (550 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (937 aa)
Deba_0425Phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (432 aa)
Deba_0465acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR005914:IPR020845; KEGG: noc:Noc_2047 acetoacetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q3J9I9 Acetoacetyl-CoA synthase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase. (650 aa)
Deba_0506COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_3084 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FBM1 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (503 aa)
cysSCOGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR015803:IPR015273:IPR009080:IPR014729:IPR 002308; KEGG: sfu:Sfum_1634 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: A0LIR9 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (483 aa)
Deba_0542Nickel transport complex, NikM subunit, transmembrane; COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: dal:Dalk_2736 hypothetical protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: B8FKQ6 Putative uncharacterized protein; PFAM: Nickel uptake substrate-specific transmembrane region. (268 aa)
Deba_0581COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR018486:IPR020845; KEGG: dal:Dalk_0694 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FJX1 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (554 aa)
Deba_0585COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dol:Dole_1973 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZT94 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (572 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (246 aa)
Deba_0682CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterProIPR011761:IPR016040:IPR016102:IPR013650:IPR 003781; KEGG: dat:HRM2_02900 hypothetical protein; PFAM: CoA-binding domain protein; ATP-grasp domain protein; SPTR: C0QFL6 Putative uncharacterized protein; PFAM: CoA binding domain. (738 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (466 aa)
Deba_0770Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR016040:IPR013221:IPR004101:IPR000713; KEGG: dps:DP2930 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Q1NLI3 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diam [...] (483 aa)
Deba_0805COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dat:HRM2_38320 AcsA3; PFAM: AMP-dependent synthetase and ligase; SPTR: C0GH76 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (536 aa)
Deba_0817FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645:IPR013221:IPR004101; KEGG: sfu:Sfum_1671 FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: A0LIV6 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase. (432 aa)
thrSCOGs: COG0441 Threonyl-tRNA synthetase; InterProIPR002320:IPR006195:IPR004154:IPR018163:IPR 018158:IPR012947:IPR002314; KEGG: dde:Dde_2639 threonyl-tRNA synthetase / Ser-tRNA(Thr) hydrolase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; Anticodon-binding domain protein; SPTR: Q30Y11 Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II [...] (627 aa)
pheSCOGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterProIPR004529:IPR006195:IPR010978:IPR004188:IPR 002319; KEGG: sfu:Sfum_0428 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; SPTR: C8QYJ1 Phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA syn [...] (335 aa)
pheTCOGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR012340:IPR 020825:IPR005147:IPR016027:IPR009061:IPR005146; KEGG: sfu:Sfum_0429 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: A0LFC7 Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synth [...] (802 aa)
Deba_0844Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (447 aa)
gatBglutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (476 aa)
Deba_0853Phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (433 aa)
Deba_0860COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_3279 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FJ42 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (552 aa)
hisSCOGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807:IPR006195:IPR004154:IPR002314:IPR 004516; KEGG: ppd:Ppro_1381 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: A1ANS7 Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; manually curated; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase. (417 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (595 aa)
Deba_0880Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR000089:IPR011053:IPR001882; KEGG: hoh:Hoch_6688 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: D0LT17 Biotin/lipoyl attachment domain-containing protein; manually curated; PFAM: Biotin-requiring enzyme. (75 aa)
Deba_0881COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR011762:IPR011763:IPR000438:IPR000022; KEGG: pdi:BDI_0075 propionyl-CoA carboxylase beta chain; PFAM: carboxyl transferase; SPTR: C1SKV2 Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta); PFAM: Carboxyl transferase domain. (522 aa)
Deba_0915Flagellar protein export ATPase FliI; COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterProIPR004100:IPR000194:IPR005714:IPR020005:IPR 003593; KEGG: dma:DMR_45080 flagellum-specific ATP synthase; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase; SPTR: Q1NVG3 ATPase FliI/YscN; TIGRFAM: flagellar protein export ATPase FliI; ATPase, FliI/YscN family; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-bin [...] (438 aa)
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (470 aa)
Deba_1017AMP-dependent synthetase and ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: dvm:DvMF_2446 phenylacetate-coenzyme A ligase, putative; PFAM: AMP-dependent synthetase and ligase; SPTR: B8DMU7 Phenylacetate-coenzyme A ligase, putative; PFAM: AMP-binding enzyme. (427 aa)
Deba_1111CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR016102:IPR016040:IPR003781; KEGG: dat:HRM2_21900 hypothetical protein; PFAM: CoA-binding domain protein; SPTR: C0QDM4 Putative uncharacterized protein; PFAM: CoA binding domain. (497 aa)
Deba_1133COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: afw:Anae109_1649 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A7HAV7 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (567 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (884 aa)
Deba_11422'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (188 aa)
Deba_1146COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR014746:IPR004809; KEGG: sat:SYN_01628 glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Q2LXX3 Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I. (443 aa)
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (565 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
Deba_1219Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (571 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR000728:IPR010918:IPR004733:IPR016188; KEGG: pca:Pcar_1293 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Q3A515 Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosp [...] (349 aa)
Deba_1278COGs: COG1610 conserved hypothetical protein; InterPro IPR019004:IPR003789; KEGG: fre:Franean1_0338 hypothetical protein; PFAM: Protein of unknown function; SPTR: A8LF59 Putative uncharacterized protein; PFAM: Yqey-like protein. (149 aa)
Deba_1289COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: dol:Dole_2557 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZWN0 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (552 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (435 aa)
purCCOGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636:IPR018236:IPR013816; KEGG: glo:Glov_3047 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: B3E940 Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase. (298 aa)
Deba_1398COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR011704:IPR003593; KEGG: adg:Adeg_0556 magnesium chelatase; PFAM: ATPase associated with various cellular activities AAA_5; PRIAM: Magnesium chelatase; SMART: AAA ATPase; SPTR: C9RBS7 Magnesium chelatase; PFAM: Magnesium chelatase, subunit ChlI. (345 aa)
Deba_1399COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR000523:IPR002035:IPR003593; KEGG: dau:Daud_1209 magnesium chelatase; PFAM: von Willebrand factor type A; magnesium chelatase ChlI subunit; PRIAM: Magnesium chelatase; SMART: von Willebrand factor type A; AAA ATPase; SPTR: B1I3V2 Magnesium chelatase; PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain. (680 aa)
leuSCOGs: COG0495 Leucyl-tRNA synthetase; InterProIPR015945:IPR013155:IPR001412:IPR014729:IPR 002302:IPR009008:IPR009080; KEGG: glo:Glov_2116 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; Arginyl-tRNA synthetase, class Ic, core; SPTR: B3E3L3 Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase family. (830 aa)
Deba_1444H+transporting two-sector ATPase E subunit; InterPro IPR002842; KEGG: bfs:BF2749 putative V-type ATP synthase subunit E; PFAM: H+transporting two-sector ATPase E subunit; SPTR: D0TNN5 ATP synthase subunit E. (210 aa)
atpA-2H+transporting two-sector ATPase alpha/beta subunit central region; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (581 aa)
atpBH+transporting two-sector ATPase alpha/beta subunit central region; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (439 aa)
Deba_1448COGs: COG1394 H+-ATPase subunit D; InterPro IPR002699; KEGG: fsu:Fisuc_2839 V-type ATPase, D subunit; PFAM: H+transporting two-sector ATPase D subunit; SPTR: Q1Q3P2 Putative uncharacterized protein; TIGRFAM: V-type ATPase, D subunit; PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D. (204 aa)
Deba_1450H+transporting two-sector ATPase C subunit; InterPro IPR002379; KEGG: pcu:pc1676 V-type ATP synthase subunit K; PFAM: H+transporting two-sector ATPase C subunit; SPTR: Q6MAJ9 Putative V-type sodium ATP synthase subunit K (NtpK); PFAM: ATP synthase subunit C. (145 aa)
Deba_1464Serine/threonine protein kinase PpkA; InterPro IPR002035; KEGG: dat:HRM2_08320 predicted serine/threonine protein kinase PpkA; SPTR: C0QJU2 Predicted serine/threonine protein kinase PpkA. (719 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (546 aa)
Deba_1481COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: hbu:Hbut_0038 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: C8QWH8 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family. (233 aa)
Deba_1493COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: dal:Dalk_2022 carboxyl transferase; PFAM: carboxyl transferase; SPTR: B8FG38 Carboxyl transferase; PFAM: Carboxyl transferase domain. (520 aa)
Deba_1622COGs: COG0430 RNA 3'-terminal phosphate cyclase; InterPro IPR013792:IPR000228:IPR013796; KEGG: pcl:Pcal_2009 RNA 3'-terminal-phosphate cyclase; PFAM: RNA 3'-terminal phosphate cyclase; RNA 3'-terminal phosphate cyclase insert region; PRIAM: RNA-3'-phosphate cyclase; SPTR: A3MXQ7 Probable RNA 3'-terminal phosphate cyclase; PFAM: RNA 3'-terminal phosphate cyclase (RTC), insert domain; RNA 3'-terminal phosphate cyclase; TIGRFAM: RNA 3'-phosphate cyclase. (356 aa)
Deba_1628AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873:IPR020845; KEGG: dol:Dole_3006 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZZ36 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (616 aa)
Deba_1674CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR016102:IPR016040:IPR003781; KEGG: dal:Dalk_3032 CoA-binding domain protein; PFAM: CoA-binding domain protein; SPTR: B8FL87 CoA-binding domain protein; PFAM: CoA binding domain. (489 aa)
Deba_1699KEGG: sfu:Sfum_4024 hypothetical protein; SPTR: A0LQI8 Putative uncharacterized protein. (402 aa)
Deba_1780COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: ctt:CtCNB1_4404 long-chain-fatty-acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0IUZ3 Long-chain-fatty-acid--CoA ligase; PFAM: AMP-binding enzyme. (548 aa)
argGCOGs: COG0137 Argininosuccinate synthase; InterPro IPR018223:IPR001518:IPR014729; KEGG: dal:Dalk_0409 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: B8FH30 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (404 aa)
Deba_1904COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR020845:IPR000873; KEGG: dal:Dalk_2448 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FB55 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (622 aa)
gatCglutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (94 aa)
gatAglutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (486 aa)
glySCOGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR002311:IPR008909:IPR006194:IPR015944; KEGG: gsu:GSU0579 glycyl-tRNA synthetase subunit beta; PFAM: glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain protein; PRIAM: Glycine--tRNA ligase; SPTR: Q1K046 Glycine--tRNA ligase; TIGRFAM: glycyl-tRNA synthetase, beta subunit; PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit. (695 aa)
glyQCOGs: COG0752 Glycyl-tRNA synthetase alpha subunit; InterPro IPR002310:IPR006194; KEGG: sat:SYN_01536 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase alpha subunit; PRIAM: Glycine--tRNA ligase; SPTR: Q2LVI0 Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit. (292 aa)
Deba_1988KEGG: dps:DP1532 hypothetical protein; SPTR: Q6AN13 Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2134). (342 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (881 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (321 aa)
queCexsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (234 aa)
Deba_2081O-antigen polymerase; InterPro IPR018271:IPR007016; KEGG: tye:THEYE_A0427 O-antigen polymerase family; PFAM: O-antigen polymerase; SPTR: B5YJ59 O-Antigen Polymerase family; PFAM: O-Antigen ligase. (422 aa)
lysSCOGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR018149:IPR004365:IPR004364:IPR016027:IPR 006195:IPR012340:IPR002313; KEGG: drt:Dret_2234 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: C8X521 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family. (513 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (662 aa)
Deba_2138COGs: COG1239 Mg-chelatase subunit ChlI; KEGG: dau:Daud_1208 magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: B1I3V1 Magnesium chelatase. (142 aa)
Deba_2144COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR000438:IPR011762:IPR011763:IPR000022; KEGG: gsu:GSU2370 acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: carboxyl transferase; SPTR: Q74AI4 Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit. (630 aa)
Deba_2173WbqC-like family protein; InterPro IPR014985; KEGG: psb:Psyr_1578 hypothetical protein; PFAM: WbqC-like family protein; SPTR: Q4ZW46 Putative uncharacterized protein; PFAM: WbqC-like protein family. (235 aa)
fhsFormate--tetrahydrofolate ligase; COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR020628:IPR000559; KEGG: dat:HRM2_16700 Fhs; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: C0QAX9 Formate--tetrahydrofolate ligase; PFAM: Formate--tetrahydrofolate ligase. (590 aa)
guaAGMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (517 aa)
Deba_2446COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: sat:SYN_00481 glutaconyl-CoA decarboxylase A subunit; PFAM: carboxyl transferase; SPTR: Q2LUY7 Glutaconyl-CoA decarboxylase A subunit; PFAM: Carboxyl transferase domain. (576 aa)
cbiA-2Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (460 aa)
Deba_2469Cobaltochelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: dal:Dalk_4060 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Cobaltochelatase; SPTR: B8FM12 Cobaltochelatase; PFAM: CobN/Magnesium Chelatase; TIGRFAM: cobaltochelatase, CobN subunit. (1264 aa)
Deba_2503COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (544 aa)
Deba_2516Magnesium chelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: cts:Ctha_2441 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: B3QX80 Cobaltochelatase; PFAM: CobN/Magnesium Chelatase. (1240 aa)
Deba_2517Cobaltochelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003006:IPR003672; KEGG: ppd:Ppro_1259 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Cobaltochelatase; SPTR: A1ANG0 Hydrogenobyrinic acid a,c-diamide cobaltochelatase; PFAM: CobN/Magnesium Chelatase; TIGRFAM: cobaltochelatase, CobN subunit. (1240 aa)
Deba_2519COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593:IPR000523; KEGG: cli:Clim_1021 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; PRIAM: Magnesium chelatase; SMART: AAA ATPase; SPTR: B3EC21 Magnesium chelatase; PFAM: Magnesium chelatase, subunit ChlI. (342 aa)
Deba_2520COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR002035:IPR000523; KEGG: ppd:Ppro_1261 magnesium chelatase; PFAM: von Willebrand factor type A; magnesium chelatase ChlI subunit; PRIAM: Magnesium chelatase; SMART: von Willebrand factor type A; SPTR: A1ANG2 Protoporphyrin IX magnesium-chelatase; PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain; TIGRFAM: cobaltochelatase subunit. (697 aa)
Deba_2565KEGG: dsh:Dshi_3225 hypothetical protein; SPTR: C6MK22 Putative uncharacterized protein. (696 aa)
Deba_2681Nickel transport complex, NikM subunit, transmembrane; COGs: COG5266 ABC-type Co2+ transport system periplasmic component; InterPro IPR019613; KEGG: dat:HRM2_23190 CbiP; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: C0QES2 CbiP; PFAM: Nickel uptake substrate-specific transmembrane region. (252 aa)
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (691 aa)
Deba_2719COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: rce:RC1_1843 propionate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B6INQ5 Propionate--CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. (634 aa)
atpB-2ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (229 aa)
atpEATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (121 aa)
Deba_2741(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (790 aa)
Deba_2748COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_2036 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FG52 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (560 aa)
Deba_2756CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterProIPR003781:IPR013650:IPR016102:IPR011761:IPR 016040; KEGG: dal:Dalk_0366 CoA-binding domain protein; PFAM: CoA-binding domain protein; ATP-grasp domain protein; SPTR: B8FGY7 CoA-binding domain protein; PFAM: CoA binding domain. (709 aa)
Deba_2772O-antigen polymerase; InterPro IPR007016; KEGG: dma:DMR_13570 hypothetical membrane protein; PFAM: O-antigen polymerase; SPTR: C4XMQ7 Hypothetical membrane protein; PFAM: O-Antigen ligase. (650 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (511 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (466 aa)
murDUDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (446 aa)
murCUDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (458 aa)
argSCOGs: COG0018 Arginyl-tRNA synthetase; InterProIPR005148:IPR015945:IPR008909:IPR014729:IPR 009080:IPR001412:IPR001278; KEGG: pca:Pcar_0742 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Q3A6K6 Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. (554 aa)
Deba_3025RimK domain protein ATP-grasp; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR013651:IPR011761; KEGG: dal:Dalk_1563 RimK domain protein ATP-grasp; PFAM: RimK domain protein ATP-grasp; SPTR: C8R0E0 RimK domain protein ATP-grasp; PFAM: RimK-like ATP-grasp domain. (290 aa)
Deba_3039COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143:IPR002829; KEGG: mta:Moth_0443 biotin/lipoate A/B protein ligase; PFAM: biotin/lipoate A/B protein ligase; protein of unknown function DUF116; SPTR: Q2RLB5 Biotin/lipoate A/B protein ligase; PFAM: Protein of unknown function DUF116; Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoyltransferase and lipoate-protein ligase. (519 aa)
Deba_3051COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_3272 AMP-binding domain protein; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FJ35 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (548 aa)
Deba_3080COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterProIPR006426:IPR000583:IPR001962:IPR017932:IPR 014729; KEGG: rrs:RoseRS_4439 asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: A5V1L8 Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing). (625 aa)
Deba_3093O-antigen polymerase; InterPro IPR007016; KEGG: hoh:Hoch_0024 O-antigen polymerase; PFAM: O-antigen polymerase; SPTR: C1ZFT0 O-Antigen Polymerase; PFAM: O-Antigen ligase. (419 aa)
Deba_3094AMP-dependent synthetase and ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: scl:sce8601 CapK related-protein; PFAM: AMP-dependent synthetase and ligase; SPTR: A9FZN1 CapK related-protein; PFAM: AMP-binding enzyme. (453 aa)
carBCOGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR016185:IPR005480:IPR005481:IPR 005479:IPR011607:IPR011761:IPR005483:IPR013817:IPR013816; KEGG: sfu:Sfum_0008 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: C8R2N3 Carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase [...] (1084 aa)
carACOGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR006274:IPR002474:IPR000991:IPR017926:IPR 001317:IPR011702:IPR006220; KEGG: sfu:Sfum_0009 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: A0LE61 Carbamoyl-phosphate synthase small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (394 aa)
Deba_3171UBA/THIF-type NAD/FAD binding protein; COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR009036:IPR000594:IPR016040; KEGG: reh:H16_A1870 ThiF/MoeB/HesA family protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: A1HS23 UBA/THIF-type NAD/FAD binding protein; PFAM: ThiF family. (270 aa)
acsA-2acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa)
glnSCOGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterProIPR004514:IPR011035:IPR020058:IPR020059:IPR 020060:IPR020061:IPR020056:IPR001412; KEGG: dvm:DvMF_1485 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; SPTR: B8DLQ7 Glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase. (566 aa)
Deba_3253COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: dol:Dole_2180 propionyl-CoA carboxylase; PFAM: carboxyl transferase; PRIAM: Methylcrotonoyl-CoA carboxylase; SPTR: A8ZUF2 Propionyl-CoA carboxylase; PFAM: Carboxyl transferase domain. (538 aa)
Deba_3254Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR016185:IPR011054:IPR005481:IPR005479:IPR 005482:IPR011761:IPR011764:IPR013817:IPR013816; KEGG: dol:Dole_2179 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: A8ZUF1 Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-term [...] (495 aa)
Deba_3255COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: dal:Dalk_4148 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: B8FMW2 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (564 aa)
Deba_3256Biotin/lipoyl attachment domain-containing protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR011053:IPR000089:IPR001882; KEGG: dol:Dole_2178 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: A8ZUF0 Biotin/lipoyl attachment domain-containing protein; PFAM: Biotin-requiring enzyme. (170 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa)
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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