STRINGSTRING
Deba_2036 Deba_2036 dapB dapB Deba_1858 Deba_1858 Deba_1382 Deba_1382 Deba_1376 Deba_1376 Deba_0793 Deba_0793 asd asd dxr dxr Deba_0537 Deba_0537 Deba_2382 Deba_2382 proA proA Deba_2766 Deba_2766 Deba_3023 Deba_3023 Deba_3180 Deba_3180 ilvC ilvC zwf zwf hemA hemA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Deba_2036NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: dat:HRM2_24110 Isf; PFAM: NADPH-dependent FMN reductase; SPTR: C0QFT7 Isf; PFAM: NADPH-dependent FMN reductase. (217 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
Deba_1858Flavodoxin/nitric oxide synthase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR008254; KEGG: nth:Nther_0880 flavodoxin/nitric oxide synthase; PFAM: flavodoxin/nitric oxide synthase; SPTR: B2A899 Flavodoxin/nitric oxide synthase; PFAM: NADPH-dependent FMN reductase. (160 aa)
Deba_1382COGs: COG0460 Homoserine dehydrogenase; InterProIPR005106:IPR001342:IPR002912:IPR019811:IPR 016204:IPR016040; KEGG: gsu:GSU1693 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Q74CI0 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (435 aa)
Deba_1376Flavoprotein WrbA; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR008254:IPR010089; KEGG: eba:ebA2303 TrpR binding protein WrbA; PFAM: flavodoxin/nitric oxide synthase; SPTR: Q5P5L5 Flavoprotein wrbA; TIGRFAM: flavoprotein WrbA; PFAM: NADPH-dependent FMN reductase; TIGRFAM: NAD(P)H:quinone oxidoreductase, type IV. (208 aa)
Deba_0793Flavodoxin; InterPro IPR008254; KEGG: sat:SYN_01229 flavodoxin; SPTR: Q2LW80 Flavodoxin; PFAM: NADPH-dependent FMN reductase. (153 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (388 aa)
Deba_0537COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020828:IPR020829:IPR020831:IPR016040:IPR 020832:IPR006424:IPR020830; KEGG: sfu:Sfum_1468 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: A0LIA5 Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehyd [...] (335 aa)
Deba_2382Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (377 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (418 aa)
Deba_2766NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: afu:AF1436 iron-sulfur flavoprotein (isf-1); PFAM: NADPH-dependent FMN reductase; SPTR: O28836 Iron-sulfur flavoprotein AF_1436; PFAM: NADPH-dependent FMN reductase. (265 aa)
Deba_3023NADPH-dependent FMN reductase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: geo:Geob_2071 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: B9M8T0 NADPH-dependent FMN reductase; PFAM: Flavodoxin-like fold. (189 aa)
Deba_31806-phosphogluconate dehydrogenase, decarboxylating; COGs: COG1023 6-phosphogluconate dehydrogenase; InterProIPR004849:IPR016040:IPR008927:IPR006115:IPR 006114:IPR006183:IPR013328:IPR016059:IPR002204; KEGG: dma:DMR_05560 putative 6-phosphogluconate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; SPTR: C4XI85 Putative 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain [...] (303 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (514 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (425 aa)
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.