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Deba_0258 | COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR002155:IPR016038; KEGG: dol:Dole_2160 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: C0GEG4 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa) | ||||
Deba_0305 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR020845; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (546 aa) | ||||
gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) | ||||
Deba_0482 | Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006656:IPR006657:IPR009010; KEGG: sfu:Sfum_0031 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: A0LE82 Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (529 aa) | ||||
Deba_0515 | Hydroxypyruvate reductase; COGs: COG2379 Putative glycerate kinase; InterPro IPR007835; KEGG: sus:Acid_0778 glycerate 2-kinase; PFAM: MOFRL domain protein; PRIAM: Hydroxypyruvate reductase; SPTR: Q02AY9 Glycerate 2-kinase; PFAM: MOFRL family. (448 aa) | ||||
Deba_0585 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dol:Dole_1973 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZT94 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (572 aa) | ||||
Deba_0690 | methylmalonyl-CoA epimerase; InterPro IPR017515:IPR004360; KEGG: sfu:Sfum_0455 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: A0LFF3 Methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. (135 aa) | ||||
Deba_0702 | HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0546 phosphatase; InterPro IPR006402:IPR006439:IPR005834; KEGG: dvm:DvMF_0135 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: B8DNN9 Haloacid dehalogenase domain protein hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfami [...] (210 aa) | ||||
Deba_0799 | Catalase; COGs: COG0753 Catalase; InterProIPR011614:IPR020835:IPR018028:IPR010582:IPR 002226; KEGG: mbu:Mbur_0523 catalase; PFAM: Catalase related subgroup; Catalase domain protein; PRIAM: Catalase; SPTR: Q12YH1 Catalase; PFAM: Catalase; Catalase-related immune-responsive; Belongs to the catalase family. (503 aa) | ||||
Deba_0881 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR011762:IPR011763:IPR000438:IPR000022; KEGG: pdi:BDI_0075 propionyl-CoA carboxylase beta chain; PFAM: carboxyl transferase; SPTR: C1SKV2 Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta); PFAM: Carboxyl transferase domain. (522 aa) | ||||
Deba_0882 | COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098:IPR014348:IPR016176:IPR006099; KEGG: tex:Teth514_1855 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: C7IS99 Methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain. (553 aa) | ||||
Deba_0883 | Cobalamin B12-binding domain protein; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006159:IPR006158; KEGG: pth:PTH_1362 methylmalonyl-CoA mutase C-terminal domain-containing protein; PFAM: cobalamin B12-binding domain protein; SPTR: A5D2I7 Methylmalonyl-CoA mutase, C-terminal domain/subunit; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain. (133 aa) | ||||
Deba_0969 | Propanoyl-CoA C-acyltransferase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR016038:IPR002155; KEGG: dat:HRM2_45290 AtoB5; PRIAM: Propanoyl-CoA C-acyltransferase; SPTR: D1JF94 Putative thiolase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa) | ||||
Deba_1146 | COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR014746:IPR004809; KEGG: sat:SYN_01628 glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Q2LXX3 Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I. (443 aa) | ||||
Deba_1293 | COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR016038:IPR016039; KEGG: cbe:Cbei_0411 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: A8U754 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) | ||||
Deba_1294 | COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR016038:IPR016039; KEGG: dol:Dole_2187 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: A8ZUF9 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) | ||||
mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa) | ||||
Deba_1491 | COGs: COG0372 Citrate synthase; InterProIPR002020:IPR019810:IPR016142:IPR010953:IPR 016141; KEGG: dal:Dalk_4974 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: B8FDL5 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (429 aa) | ||||
Deba_1497 | Kynurenine formamidase; COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: gme:Gmet_0042 putative cyclase; PFAM: cyclase family protein; PRIAM: Arylformamidase; SPTR: Q39ZN2 Putative cyclase; PFAM: Putative cyclase. (208 aa) | ||||
Deba_1534 | COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR016038; KEGG: tac:Ta0351 acetyl-CoA acetyltransferase; SPTR: Q9HL79 Sterol carrier protein x/sterol carrier protein 2 related protein. (478 aa) | ||||
Deba_1536 | D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR016166:IPR016164:IPR006094:IPR004113:IPR 016167:IPR016168:IPR000542; KEGG: dat:HRM2_18570 GlcD2; PFAM: FAD linked oxidase domain protein; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: C0QBU7 GlcD2; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (463 aa) | ||||
Deba_1537 | Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR009051:IPR004017:IPR012285:IPR017896:IPR 017900; KEGG: gem:GM21_0576 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C6DZR8 Putative uncharacterized protein; PFAM: Cysteine-rich domain. (393 aa) | ||||
Deba_2119 | Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR009010:IPR006656:IPR006657; KEGG: sfu:Sfum_0031 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: A0LE82 Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (529 aa) | ||||
acsA | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (662 aa) | ||||
Deba_2192 | Aconitate hydratase; COGs: COG1048 Aconitase A; InterProIPR001030:IPR015928:IPR015931:IPR015932:IPR 000573:IPR006250; KEGG: glo:Glov_1612 aconitate hydratase; PFAM: aconitate hydratase domain protein; SPTR: Q1NKB5 Putative aconitate hydratase; TIGRFAM: aconitate hydratase; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type. (639 aa) | ||||
Deba_2198 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR016156:IPR013027:IPR000815:IPR004099:IPR 012999:IPR006258; KEGG: dsa:Desal_3027 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C6C0Y2 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (478 aa) | ||||
Deba_2213 | HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005833:IPR005834:IPR006439; KEGG: dal:Dalk_3700 HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: B8FLN4 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif [...] (214 aa) | ||||
Deba_2449 | COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR016038:IPR016039; KEGG: dae:Dtox_1701 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: C8VWY2 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) | ||||
Deba_2503 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (544 aa) | ||||
Deba_2981 | COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR004099:IPR000815:IPR016156:IPR 012999:IPR006258; KEGG: mta:Moth_1763 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: A1HU83 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (456 aa) | ||||
gcvH-2 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (139 aa) | ||||
Deba_3040 | COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); InterPro IPR011053:IPR002930:IPR003016; KEGG: mta:Moth_0438 glycine cleavage system H protein; PFAM: glycine cleavage H-protein; SPTR: Q2RLC0 Glycine cleavage system H protein; PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein. (144 aa) | ||||
glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa) | ||||
Deba_3132 | Propanoyl-CoA C-acyltransferase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR002155:IPR016038; KEGG: dal:Dalk_3190 acetyl-CoA acetyltransferase; PRIAM: Propanoyl-CoA C-acyltransferase; SPTR: B8FGH1 Propanoyl-CoA C-acyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) | ||||
acsA-2 | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa) |