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Deba_0092 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004839:IPR015424:IPR004838:IPR001176:IPR 015421; KEGG: dol:Dole_1584 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A8ZZY8 Aminotransferase class I and II; PFAM: Aminotransferase class I and II. (395 aa) | ||||
Deba_0239 | CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR007202:IPR016041:IPR011005:IPR016218; KEGG: dal:Dalk_0682 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: B8FJV9 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit. (447 aa) | ||||
Deba_0241 | Carbon-monoxide dehydrogenase, catalytic subunit; COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterProIPR004137:IPR011254:IPR010047:IPR016101:IPR 016099; KEGG: dat:HRM2_16670 CdhA; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: C0QAX6 CdhA; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit. (688 aa) | ||||
Deba_0243 | COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041:IPR011005; KEGG: dol:Dole_3186 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: A9A070 CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase, delta subunit. (531 aa) | ||||
Deba_0305 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR020845; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (546 aa) | ||||
Deba_0482 | Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006656:IPR006657:IPR009010; KEGG: sfu:Sfum_0031 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: A0LE82 Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (529 aa) | ||||
Deba_0487 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR019575:IPR013027:IPR009051:IPR012285:IPR 016040:IPR000759:IPR001949; KEGG: dds:Ddes_1543 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: B8J118 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; manually curated; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH-u [...] (641 aa) | ||||
Deba_0488 | Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR019574:IPR001450:IPR006963:IPR 006656:IPR017896:IPR017900; KEGG: sfu:Sfum_3509 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LP28 Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; 4Fe-4S bind [...] (778 aa) | ||||
Deba_0515 | Hydroxypyruvate reductase; COGs: COG2379 Putative glycerate kinase; InterPro IPR007835; KEGG: sus:Acid_0778 glycerate 2-kinase; PFAM: MOFRL domain protein; PRIAM: Hydroxypyruvate reductase; SPTR: Q02AY9 Glycerate 2-kinase; PFAM: MOFRL family. (448 aa) | ||||
gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (237 aa) | ||||
Deba_0585 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dol:Dole_1973 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZT94 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (572 aa) | ||||
Deba_0704 | COGs: COG2191 Formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: aba:Acid345_0503 formylmethanofuran dehydrogenase, subunit E; PFAM: formylmethanofuran dehydrogenase subunit E region; SPTR: Q1IUE2 Formylmethanofuran dehydrogenase, subunit E; PFAM: FmdE, Molybdenum formylmethanofuran dehydrogenase operon. (215 aa) | ||||
pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (446 aa) | ||||
Deba_0722 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR016040:IPR006139:IPR006140; KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: B8FLC2 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase. (316 aa) | ||||
Deba_0781 | COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: dal:Dalk_5067 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: B8FDV7 CoB--CoM heterodisulfide reductase; PFAM: Cysteine-rich domain. (288 aa) | ||||
Deba_0787 | Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR017896:IPR001450:IPR003813; KEGG: dal:Dalk_2269 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8FIH2 Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit. (810 aa) | ||||
Deba_0887 | COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterProIPR017896:IPR001450:IPR007516:IPR007525:IPR 017900; KEGG: dal:Dalk_2982 coenzyme F420 hydrogenase; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: Coenzyme F420 hydrogenase; SPTR: B8FL37 Coenzyme F420 hydrogenase; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. (360 aa) | ||||
fbp | Inositol phosphatase/fructose-16-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; InterPro IPR000146:IPR020548; KEGG: dvm:DvMF_0404 fructose-1,6-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; SPTR: C0GQU0 Inositol phosphatase/fructose-16-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase. (341 aa) | ||||
Deba_0986 | COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: dae:Dtox_3573 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: C8VVZ8 CoB--CoM heterodisulfide reductase; PFAM: Cysteine-rich domain. (292 aa) | ||||
Deba_1180 | 2-phosphosulfolactate phosphatase; COGs: COG2045 Phosphosulfolactate phosphohydrolase; InterPro IPR005238; KEGG: ttu:TERTU_0169 putative 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase; SPTR: C5BLF2 Putative 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (225 aa) | ||||
gpmA-2 | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (271 aa) | ||||
mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa) | ||||
ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa) | ||||
Deba_1380 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (708 aa) | ||||
Deba_1383 | Proposed homoserine kinase; COGs: COG3635 phosphoglycerate mutase AP superfamily; InterProIPR019304:IPR006124:IPR004456:IPR013371:IPR 017850; KEGG: pca:Pcar_1514 cofactor-independent phosphoglycerate mutase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Q3A4E7 Phosphoglycerate mutase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme superfamily; TIGRFAM: 2,3-bisphosphoglycerate-inde [...] (398 aa) | ||||
rnfB | Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (695 aa) | ||||
eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa) | ||||
Deba_2022 | COGs: COG0247 Fe-S oxidoreductase; InterPro IPR017900:IPR004017:IPR009051:IPR012285; KEGG: dae:Dtox_1734 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C8VX15 Putative uncharacterized protein; PFAM: Cysteine-rich domain. (380 aa) | ||||
Deba_2119 | Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR009010:IPR006656:IPR006657; KEGG: sfu:Sfum_0031 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: A0LE82 Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (529 aa) | ||||
acsA | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (662 aa) | ||||
Deba_2131 | COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: sfu:Sfum_2154 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: A0LK84 Methyl-viologen-reducing hydrogenase, delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit. (141 aa) | ||||
Deba_2132 | FAD dependent oxidoreductase; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR016040:IPR017896:IPR017900:IPR001450:IPR 006076; KEGG: dal:Dalk_0247 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD dependent oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8FMT9 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; FAD dependent oxidoreductase. (1012 aa) | ||||
Deba_2133 | COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dal:Dalk_3063 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: B8FBK0 Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit. (151 aa) | ||||
Deba_2134 | InterPro IPR009051:IPR017896:IPR017900; KEGG: dal:Dalk_5062 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8FDV2 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. (316 aa) | ||||
Deba_2150 | FAD dependent oxidoreductase; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR013027:IPR000103:IPR016040:IPR017896:IPR 017900:IPR003953:IPR001450:IPR006076; KEGG: sfu:Sfum_3133 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: FAD dependent oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LN04 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: FAD binding domain; 4Fe-4S binding domain; FAD dependent oxidoreductase. (1011 aa) | ||||
Deba_2234 | Ketose-bisphosphate aldolase class-II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR013785:IPR000771; KEGG: gur:Gura_3299 fructose/tagatose bisphosphate aldolase-like protein; PFAM: ketose-bisphosphate aldolase class-II; SPTR: A5G6N8 Fructose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II. (428 aa) | ||||
gpmI | Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (517 aa) | ||||
Deba_2503 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (544 aa) | ||||
Deba_2985 | Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR001450:IPR004017:IPR012285:IPR017896:IPR 009051:IPR017900; KEGG: mac:MA0688 heterodisulfide reductase, subunit D; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q8TSV7 CoB--CoM heterodisulfide reductase 2 iron-sulfur subunit D; PFAM: Cysteine-rich domain. (399 aa) | ||||
Deba_3064 | Pyruvate, water dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR008279:IPR002192:IPR013815; KEGG: sfu:Sfum_2666 pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PRIAM: Pyruvate, water dikinase; SPTR: A0LLP2 Phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (876 aa) | ||||
glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa) | ||||
Deba_3073 | COGs: COG2191 Formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: mtp:Mthe_1665 formylmethanofuran dehydrogenase, subunit E region; PFAM: formylmethanofuran dehydrogenase subunit E region; SPTR: A0B9Q7 Formylmethanofuran dehydrogenase, subunit E region; PFAM: Prokaryotic dksA/traR C4-type zinc finger; FmdE, Molybdenum formylmethanofuran dehydrogenase operon. (185 aa) | ||||
acsA-2 | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa) | ||||
Deba_3201 | Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sfu:Sfum_2795 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0LM21 Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (320 aa) | ||||
Deba_3202 | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR009014:IPR002880:IPR015941; KEGG: sfu:Sfum_2794 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: A0LM20 Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: domain. (391 aa) | ||||
Deba_3203 | COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898:IPR001450:IPR017896:IPR017900; KEGG: sfu:Sfum_2793 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LM19 Pyruvate ferredoxin oxidoreductase, delta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family. (109 aa) | ||||
Deba_3204 | Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR011894:IPR002869:IPR019752; KEGG: sat:SYN_00157 pyruvate:ferredoxin oxidoreductase gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: Q2LYF2 Pyruvate:ferredoxin oxidoreductase gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate [...] (182 aa) |