node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Deba_0336 | Deba_0337 | Deba_0336 | Deba_0337 | Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012001:IPR012000:IPR011766:IPR012846:IPR 000399; KEGG: mtp:Mthe_0110 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0B5D8 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, [...] | COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: pth:PTH_0528 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: A5D4Z3 Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit. | 0.999 |
Deba_0336 | Deba_0847 | Deba_0336 | Deba_0847 | Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012001:IPR012000:IPR011766:IPR012846:IPR 000399; KEGG: mtp:Mthe_0110 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0B5D8 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, [...] | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544:IPR018300; KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: C8R2U2 Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. | 0.608 |
Deba_0336 | Deba_1258 | Deba_0336 | Deba_1258 | Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012001:IPR012000:IPR011766:IPR012846:IPR 000399; KEGG: mtp:Mthe_0110 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0B5D8 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, [...] | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase. | 0.638 |
Deba_0336 | ilvC | Deba_0336 | Deba_0338 | Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012001:IPR012000:IPR011766:IPR012846:IPR 000399; KEGG: mtp:Mthe_0110 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0B5D8 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, [...] | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
Deba_0336 | ilvD | Deba_0336 | Deba_0335 | Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012001:IPR012000:IPR011766:IPR012846:IPR 000399; KEGG: mtp:Mthe_0110 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0B5D8 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, [...] | COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR004404:IPR020558; KEGG: mja:MJ1276 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: C5U5V1 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.994 |
Deba_0337 | Deba_0336 | Deba_0337 | Deba_0336 | COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: pth:PTH_0528 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: A5D4Z3 Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit. | Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012001:IPR012000:IPR011766:IPR012846:IPR 000399; KEGG: mtp:Mthe_0110 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0B5D8 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, [...] | 0.999 |
Deba_0337 | Deba_0847 | Deba_0337 | Deba_0847 | COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: pth:PTH_0528 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: A5D4Z3 Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit. | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544:IPR018300; KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: C8R2U2 Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. | 0.614 |
Deba_0337 | ilvC | Deba_0337 | Deba_0338 | COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: pth:PTH_0528 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: A5D4Z3 Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
Deba_0337 | ilvD | Deba_0337 | Deba_0335 | COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: pth:PTH_0528 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: A5D4Z3 Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit. | COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR004404:IPR020558; KEGG: mja:MJ1276 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: C5U5V1 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.986 |
Deba_0847 | Deba_0336 | Deba_0847 | Deba_0336 | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544:IPR018300; KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: C8R2U2 Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. | Acetolactate synthase, large subunit, biosynthetic type; COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterProIPR012001:IPR012000:IPR011766:IPR012846:IPR 000399; KEGG: mtp:Mthe_0110 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0B5D8 Acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, [...] | 0.608 |
Deba_0847 | Deba_0337 | Deba_0847 | Deba_0337 | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544:IPR018300; KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: C8R2U2 Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. | COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: pth:PTH_0528 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: A5D4Z3 Acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit. | 0.614 |
Deba_0847 | Deba_1258 | Deba_0847 | Deba_1258 | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544:IPR018300; KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: C8R2U2 Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. | COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase. | 0.439 |
Deba_0847 | ilvC | Deba_0847 | Deba_0338 | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544:IPR018300; KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: C8R2U2 Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.573 |
Deba_0847 | ilvD | Deba_0847 | Deba_0335 | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544:IPR018300; KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: C8R2U2 Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. | COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR004404:IPR020558; KEGG: mja:MJ1276 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: C5U5V1 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.985 |
Deba_0847 | panB | Deba_0847 | Deba_1326 | COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786:IPR001544:IPR018300; KEGG: bsu:BSU38550 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: C8R2U2 Branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.920 |
Deba_0953 | Deba_1219 | Deba_0953 | Deba_1219 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: scl:sce4803 hypothetical protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: A9FF91 Putative uncharacterized protein mazG; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.900 |
Deba_0953 | acpS | Deba_0953 | Deba_0947 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: scl:sce4803 hypothetical protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: A9FF91 Putative uncharacterized protein mazG; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.519 |
Deba_0953 | coaE | Deba_0953 | Deba_0733 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: scl:sce4803 hypothetical protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: A9FF91 Putative uncharacterized protein mazG; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.908 |
Deba_0953 | coaX | Deba_0953 | Deba_0767 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: scl:sce4803 hypothetical protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: A9FF91 Putative uncharacterized protein mazG; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.905 |
Deba_1219 | Deba_0953 | Deba_1219 | Deba_0953 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: scl:sce4803 hypothetical protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: A9FF91 Putative uncharacterized protein mazG; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | 0.900 |