STRINGSTRING
Deba_0032 Deba_0032 Deba_0086 Deba_0086 Deba_0088 Deba_0088 gltX gltX Deba_0117 Deba_0117 Deba_0121 Deba_0121 ubiX ubiX pgl pgl zwf zwf Deba_0224 Deba_0224 Deba_0238 Deba_0238 Deba_0239 Deba_0239 Deba_0240 Deba_0240 Deba_0241 Deba_0241 Deba_0243 Deba_0243 Deba_0258 Deba_0258 Deba_0305 Deba_0305 Deba_0329 Deba_0329 hemA hemA Deba_0366 Deba_0366 Deba_0396 Deba_0396 sat sat Deba_0425 Deba_0425 Deba_0439 Deba_0439 Deba_0440 Deba_0440 nifH nifH Deba_0467 Deba_0467 Deba_0482 Deba_0482 Deba_0487 Deba_0487 Deba_0488 Deba_0488 Deba_0515 Deba_0515 Deba_0530 Deba_0530 Deba_0537 Deba_0537 Deba_0564 Deba_0564 gpmA gpmA Deba_0572 Deba_0572 hemL hemL Deba_0585 Deba_0585 Deba_0626 Deba_0626 Deba_0663 Deba_0663 Deba_0670 Deba_0670 Deba_0690 Deba_0690 Deba_0704 Deba_0704 pfkA pfkA Deba_0722 Deba_0722 prs prs asd asd Deba_0781 Deba_0781 Deba_0787 Deba_0787 hemC hemC Deba_0815 Deba_0815 Deba_0853 Deba_0853 Deba_0881 Deba_0881 Deba_0882 Deba_0882 Deba_0883 Deba_0883 Deba_0887 Deba_0887 Deba_0894 Deba_0894 fbp fbp Deba_0944 Deba_0944 Deba_0959 Deba_0959 Deba_0960 Deba_0960 Deba_0969 Deba_0969 Deba_0981 Deba_0981 Deba_0982 Deba_0982 Deba_0986 Deba_0986 Deba_0997 Deba_0997 Deba_1009 Deba_1009 Deba_1017 Deba_1017 Deba_1025 Deba_1025 Deba_1036 Deba_1036 Deba_1037 Deba_1037 Deba_1038 Deba_1038 Deba_1051 Deba_1051 Deba_1088 Deba_1088 Deba_1089 Deba_1089 Deba_1090 Deba_1090 Deba_1091 Deba_1091 Deba_1092 Deba_1092 Deba_1093 Deba_1093 Deba_1110 Deba_1110 Deba_1111 Deba_1111 Deba_1112 Deba_1112 Deba_1114 Deba_1114 Deba_1146 Deba_1146 Deba_1151 Deba_1151 Deba_1152 Deba_1152 Deba_1163 Deba_1163 Deba_1177 Deba_1177 Deba_1178 Deba_1178 Deba_1180 Deba_1180 sucD sucD sucC sucC Deba_1258 Deba_1258 Deba_1275 Deba_1275 Deba_1293 Deba_1293 Deba_1294 Deba_1294 folD folD gpmA-2 gpmA-2 ectC ectC Deba_1357 Deba_1357 ectA ectA Deba_1359 Deba_1359 mdh mdh Deba_1368 Deba_1368 ackA ackA Deba_1380 Deba_1380 Deba_1382 Deba_1382 Deba_1383 Deba_1383 Deba_1385 Deba_1385 Deba_1395 Deba_1395 Deba_1491 Deba_1491 Deba_1534 Deba_1534 Deba_1536 Deba_1536 Deba_1537 Deba_1537 Deba_1649 Deba_1649 Deba_1674 Deba_1674 Deba_1675 Deba_1675 Deba_1707 Deba_1707 rnfB rnfB Deba_1863 Deba_1863 Deba_1864 Deba_1864 tal tal dapB dapB dapA dapA dapF dapF lysA lysA argD argD pgi pgi Deba_1951 Deba_1951 Deba_1952 Deba_1952 Deba_1953 Deba_1953 Deba_1954 Deba_1954 pgk pgk tpiA tpiA eno eno Deba_2022 Deba_2022 Deba_2119 Deba_2119 acsA acsA Deba_2131 Deba_2131 Deba_2132 Deba_2132 Deba_2133 Deba_2133 Deba_2134 Deba_2134 Deba_2141 Deba_2141 Deba_2149 Deba_2149 Deba_2150 Deba_2150 Deba_2153 Deba_2153 Deba_2159 Deba_2159 Deba_2160 Deba_2160 Deba_2192 Deba_2192 Deba_2198 Deba_2198 Deba_2224 Deba_2224 fhs fhs Deba_2234 Deba_2234 Deba_2279 Deba_2279 Deba_2360 Deba_2360 Deba_2361 Deba_2361 Deba_2362 Deba_2362 Deba_2363 Deba_2363 Deba_2385 Deba_2385 gpmI gpmI Deba_2444 Deba_2444 Deba_2446 Deba_2446 Deba_2447 Deba_2447 Deba_2449 Deba_2449 Deba_2450 Deba_2450 Deba_2451 Deba_2451 Deba_2503 Deba_2503 Deba_2621 Deba_2621 Deba_2692 Deba_2692 Deba_2695 Deba_2695 Deba_2710 Deba_2710 Deba_2756 Deba_2756 Deba_2842 Deba_2842 Deba_2849 Deba_2849 Deba_2850 Deba_2850 Deba_2851 Deba_2851 Deba_2852 Deba_2852 Deba_2958 Deba_2958 Deba_2981 Deba_2981 Deba_2985 Deba_2985 Deba_3064 Deba_3064 glyA glyA Deba_3073 Deba_3073 Deba_3094 Deba_3094 Deba_3132 Deba_3132 Deba_3180 Deba_3180 acsA-2 acsA-2 Deba_3201 Deba_3201 Deba_3202 Deba_3202 Deba_3203 Deba_3203 Deba_3204 Deba_3204 cysC cysC Deba_3254 Deba_3254
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Deba_0032COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterProIPR001753:IPR006176:IPR008927:IPR016040:IPR 013328; KEGG: hoh:Hoch_3456 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; SPTR: D0LW26 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family. (572 aa)
Deba_0086COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR001753:IPR006176:IPR006108:IPR016040:IPR 008927:IPR018376:IPR013328; KEGG: 3-hydroxyacyl-CoA dehyrogenase, putative; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; SPTR: B9RKN5 3-hydroxyacyl-CoA dehyrogenase, putative; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Belongs to the enoyl-CoA hydratase/isomerase family. (709 aa)
Deba_0088COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR002155:IPR016038; KEGG: afu:AF1028 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: O29234 3-ketoacyl-CoA thiolase (FadA-1); TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (471 aa)
Deba_0117COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015824; KEGG: dal:Dalk_0244 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: B8FMT6 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase. (436 aa)
Deba_0121Phosphoglucomutase, alpha-D-glucose phosphate-specific; COGs: COG0033 Phosphoglucomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 016055:IPR016066:IPR005852; KEGG: gur:Gura_2654 phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: A5G4W1 Phosphoglucomutase, alpha-D-glucose phosphate-specific; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: [...] (548 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (193 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (240 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (514 aa)
Deba_0224Transketolase; COGs: COG0021 Transketolase; InterProIPR005474:IPR005475:IPR005476:IPR009014:IPR 005478:IPR015941; KEGG: pna:Pnap_4499 transketolase; PFAM: Transketolase domain protein; Transketolase central region; SPTR: A6C7Q1 Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family. (666 aa)
Deba_0238Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR000489:IPR011005; KEGG: dol:Dole_3182 dihydropteroate synthase DhpS; PFAM: dihydropteroate synthase DHPS; SPTR: A9A066 Dihydropteroate synthase DHPS; PFAM: Pterin binding enzyme. (293 aa)
Deba_0239CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; COGs: COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein); InterPro IPR007202:IPR016041:IPR011005:IPR016218; KEGG: dal:Dalk_0682 acetyl-CoA decarbonylase/synthase complex subunit gamma; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; Fe-S cluster domain protein; SPTR: B8FJV9 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; PFAM: Putative Fe-S cluster; CO dehydrogenase/acetyl-CoA synthase delta subunit. (447 aa)
Deba_0240COGs: COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit; InterPro IPR004461:IPR011254:IPR016099; KEGG: dal:Dalk_0681 bifunctional acetyl-CoA decarbonylase/synthase complex subunit alpha/beta; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; PRIAM: CO-methylating acetyl-CoA synthase; SPTR: B8FJV8 CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase complex beta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase complex, beta subunit. (736 aa)
Deba_0241Carbon-monoxide dehydrogenase, catalytic subunit; COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterProIPR004137:IPR011254:IPR010047:IPR016101:IPR 016099; KEGG: dat:HRM2_16670 CdhA; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: C0QAX6 CdhA; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit. (688 aa)
Deba_0243COGs: COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein); InterPro IPR016041:IPR011005; KEGG: dol:Dole_3186 acetyl-CoA decarbonylase/synthase complex subunit delta; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel; SPTR: A9A070 CO dehydrogenase/acetyl-CoA synthase delta subunit; PFAM: CO dehydrogenase/acetyl-CoA synthase delta subunit; TIGRFAM: CO dehydrogenase/acetyl-CoA synthase, delta subunit. (531 aa)
Deba_0258COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR002155:IPR016038; KEGG: dol:Dole_2160 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: C0GEG4 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
Deba_0305COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873:IPR020845; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (546 aa)
Deba_0329COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040:IPR006367; KEGG: sfu:Sfum_1588 siroheme synthase; SPTR: A0LIM3 Precorrin-2 dehydrogenase; TIGRFAM: siroheme synthase; TIGRFAM: siroheme synthase, N-terminal domain. (232 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (425 aa)
Deba_0366COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056:IPR011060:IPR013785; KEGG: gyc:GYMC61_1959 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: C9RZQ3 Ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase. (219 aa)
Deba_0396ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: gbm:Gbem_1326 ROK family protein; PFAM: ROK family protein; SPTR: B5EI81 ROK family protein; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (307 aa)
satCOGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002650:IPR015947:IPR014729; KEGG: abo:ABO_0730 sulfate adenylyltransferase; PFAM: ATP-sulfurylase; PRIAM: Sulfate adenylyltransferase; SPTR: B9ZMM6 Sulfate adenylyltransferase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase; Belongs to the sulfate adenylyltransferase family. (401 aa)
Deba_0425Phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (432 aa)
Deba_0439Nitrogenase molybdenum-iron protein beta chain; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family. (459 aa)
Deba_0440COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000510:IPR005972:IPR010143:IPR000318; KEGG: dsa:Desal_0444 nitrogenase molybdenum-iron protein alpha chain; PFAM: oxidoreductase/nitrogenase component 1; PRIAM: Nitrogenase; SPTR: C8R0M9 Nitrogenase molybdenum-iron protein alpha chain; TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component I, alpha chain; PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: nitrogenase component I, alpha chain; nitrogenase molybdenum-iron protein alpha chain. (547 aa)
nifHNitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (275 aa)
Deba_0467COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027:IPR000103; KEGG: dal:Dalk_2354 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8FAW1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. (400 aa)
Deba_0482Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006656:IPR006657:IPR009010; KEGG: sfu:Sfum_0031 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: A0LE82 Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (529 aa)
Deba_0487FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR019575:IPR013027:IPR009051:IPR012285:IPR 016040:IPR000759:IPR001949; KEGG: dds:Ddes_1543 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: B8J118 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; manually curated; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH-u [...] (641 aa)
Deba_0488Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR019574:IPR001450:IPR006963:IPR 006656:IPR017896:IPR017900; KEGG: sfu:Sfum_3509 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LP28 Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; 4Fe-4S bind [...] (778 aa)
Deba_0515Hydroxypyruvate reductase; COGs: COG2379 Putative glycerate kinase; InterPro IPR007835; KEGG: sus:Acid_0778 glycerate 2-kinase; PFAM: MOFRL domain protein; PRIAM: Hydroxypyruvate reductase; SPTR: Q02AY9 Glycerate 2-kinase; PFAM: MOFRL family. (448 aa)
Deba_0530COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: similar to peroxisomal enoyl-coenzyme A hydratase-like protein; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C9Y8M4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; PFAM: Enoyl-CoA hydratase/isomerase family. (274 aa)
Deba_0537COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020828:IPR020829:IPR020831:IPR016040:IPR 020832:IPR006424:IPR020830; KEGG: sfu:Sfum_1468 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: A0LIA5 Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehyd [...] (335 aa)
Deba_0564COGs: COG2181 Nitrate reductase gamma subunit; InterPro IPR003816; KEGG: drt:Dret_0235 nitrate reductase gamma subunit; PFAM: Nitrate reductase gamma subunit; SPTR: C8WZR2 Membrane-bound menaquinol oxidoreductase, cytochrome b subunit; PFAM: Nitrate reductase gamma subunit. (355 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (237 aa)
Deba_0572Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: mrd:Mrad2831_2432 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B1LZ06 Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (374 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814:IPR015424:IPR015421:IPR004639; KEGG: pca:Pcar_0266 glutamate-1-semialdehyde aminotransferase; PFAM: aminotransferase class-III; SPTR: Q3A7W5 Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. (427 aa)
Deba_0585COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dol:Dole_1973 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZT94 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (572 aa)
Deba_0626Vinylacetyl-CoA Delta-isomerase; COGs: COG2368 Aromatic ring hydroxylase; InterPro IPR006091:IPR013764:IPR004925; KEGG: cbe:Cbei_2100 vinylacetyl-CoA delta-isomerase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; PRIAM: Vinylacetyl-CoA Delta-isomerase; SPTR: A6LV87 Vinylacetyl-CoA Delta-isomerase; PFAM: 4-hydroxyphenylacetate 3-hydroxylase N terminal; 4-hydroxyphenylacetate 3-hydroxylase C terminal. (482 aa)
Deba_0663COGs: COG0599 gamma-carboxymuconolactone decarboxylase subunit; InterPro IPR003779; KEGG: sml:Smlt1304 putative 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase; SPTR: B2FTF6 Putative 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase family. (128 aa)
Deba_0670COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753:IPR018376; KEGG: acr:Acry_1715 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: A5FZ87 Enoyl-CoA hydratase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (268 aa)
Deba_0690methylmalonyl-CoA epimerase; InterPro IPR017515:IPR004360; KEGG: sfu:Sfum_0455 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: A0LFF3 Methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase. (135 aa)
Deba_0704COGs: COG2191 Formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: aba:Acid345_0503 formylmethanofuran dehydrogenase, subunit E; PFAM: formylmethanofuran dehydrogenase subunit E region; SPTR: Q1IUE2 Formylmethanofuran dehydrogenase, subunit E; PFAM: FmdE, Molybdenum formylmethanofuran dehydrogenase operon. (215 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (446 aa)
Deba_0722D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR016040:IPR006139:IPR006140; KEGG: dal:Dalk_3379 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: B8FLC2 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase. (316 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
Deba_0781COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: dal:Dalk_5067 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: B8FDV7 CoB--CoM heterodisulfide reductase; PFAM: Cysteine-rich domain. (288 aa)
Deba_0787Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR017896:IPR001450:IPR003813; KEGG: dal:Dalk_2269 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8FIH2 Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit. (810 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (310 aa)
Deba_0815uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. (509 aa)
Deba_0853Phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (433 aa)
Deba_0881COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR011762:IPR011763:IPR000438:IPR000022; KEGG: pdi:BDI_0075 propionyl-CoA carboxylase beta chain; PFAM: carboxyl transferase; SPTR: C1SKV2 Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta); PFAM: Carboxyl transferase domain. (522 aa)
Deba_0882COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098:IPR014348:IPR016176:IPR006099; KEGG: tex:Teth514_1855 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: C7IS99 Methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain. (553 aa)
Deba_0883Cobalamin B12-binding domain protein; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006159:IPR006158; KEGG: pth:PTH_1362 methylmalonyl-CoA mutase C-terminal domain-containing protein; PFAM: cobalamin B12-binding domain protein; SPTR: A5D2I7 Methylmalonyl-CoA mutase, C-terminal domain/subunit; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain. (133 aa)
Deba_0887COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterProIPR017896:IPR001450:IPR007516:IPR007525:IPR 017900; KEGG: dal:Dalk_2982 coenzyme F420 hydrogenase; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: Coenzyme F420 hydrogenase; SPTR: B8FL37 Coenzyme F420 hydrogenase; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. (360 aa)
Deba_0894Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: hmo:HM1_2316 dhh family domain protein, putative; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: B0THR6 Dhh family domain protein, putative; PFAM: DHH family; DHHA1 domain. (318 aa)
fbpInositol phosphatase/fructose-16-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; InterPro IPR000146:IPR020548; KEGG: dvm:DvMF_0404 fructose-1,6-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; SPTR: C0GQU0 Inositol phosphatase/fructose-16-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase. (341 aa)
Deba_0944COGs: COG0527 Aspartokinase; InterProIPR001057:IPR001048:IPR002912:IPR018042:IPR 001341:IPR005260; KEGG: pca:Pcar_1006 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Q3A5V0 Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family. (414 aa)
Deba_0959COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterProIPR005117:IPR006067:IPR001450:IPR017900:IPR 017896:IPR011808; KEGG: sfu:Sfum_4043 sulfite reductase, dissimilatory-type beta subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: Hydrogensulfite reductase; SPTR: A0LQK7 Sulfite reductase, dissimilatory-type beta subunit; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: Nitrite an [...] (361 aa)
Deba_0960COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR006067:IPR011806; KEGG: dal:Dalk_4301 sulfite reductase, dissimilatory-type alpha subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; PRIAM: Hydrogensulfite reductase; SPTR: Q93EU9 Dissimilatory sulfite reductase alpha subunit (Fragment); TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit. (423 aa)
Deba_0969Propanoyl-CoA C-acyltransferase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR016038:IPR002155; KEGG: dat:HRM2_45290 AtoB5; PRIAM: Propanoyl-CoA C-acyltransferase; SPTR: D1JF94 Putative thiolase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
Deba_0981InterPro IPR001450:IPR017900:IPR017896:IPR011802; KEGG: sfu:Sfum_1047 adenylylsulfate reductase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A6ZJS6 AprB (Fragment); TIGRFAM: adenylylsulfate reductase, beta subunit; PFAM: Adenosine-5'-phosphosulfate reductase beta subunit; TIGRFAM: adenosine phosphosulphate reductase, beta subunit. (151 aa)
Deba_0982Dissimilatory adenylylsulfate reductase alpha subunit precursor; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR015939:IPR003953:IPR011803; KEGG: sfu:Sfum_1048 adenylylsulfate reductase subunit alpha; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: A6ZJS7 AprA (Fragment); TIGRFAM: adenylylsulfate reductase, alpha subunit; PFAM: domain; FAD binding domain; TIGRFAM: adenosine phosphosulphate reductase, alpha subunit. (622 aa)
Deba_0986COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: dae:Dtox_3573 CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: C8VVZ8 CoB--CoM heterodisulfide reductase; PFAM: Cysteine-rich domain. (292 aa)
Deba_0997COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterProIPR001821:IPR019546:IPR006137:IPR016160:IPR 017909:IPR006311; KEGG: dps:DP0160 periplasmic [NiFeSe] hydrogenase, small subunit [precursor]; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Twin-arginine translocation pathway, signal sequence, subgroup; PRIAM: Hydrogenase (acceptor); SPTR: Q6ARY6 Related to periplasmic [NiFeSe] hydrogenase, small subunit [Precursor]; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal seq [...] (309 aa)
Deba_1009Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR011005:IPR000489; KEGG: dal:Dalk_4619 dihydropteroate synthase DhpS; PFAM: dihydropteroate synthase DHPS; SPTR: B8FNL6 Dihydropteroate synthase DHPS; PFAM: Pterin binding enzyme. (264 aa)
Deba_1017AMP-dependent synthetase and ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: dvm:DvMF_2446 phenylacetate-coenzyme A ligase, putative; PFAM: AMP-dependent synthetase and ligase; SPTR: B8DMU7 Phenylacetate-coenzyme A ligase, putative; PFAM: AMP-binding enzyme. (427 aa)
Deba_1025Aminotransferase class-III; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR015424:IPR005814:IPR015421; KEGG: nwi:Nwi_2388 aminotransferase class-III; PFAM: aminotransferase class-III; SPTR: Q3SPZ9 Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
Deba_1036COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: amc:MADE_02638 enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: B4RTC8 Enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family. (230 aa)
Deba_1037COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766:IPR011896; KEGG: drt:Dret_0516 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: C8X0I8 Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; T [...] (283 aa)
Deba_1038Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002869:IPR009014:IPR019752:IPR002880; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; SPTR: B8DNT7 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase. (560 aa)
Deba_1051Vinylacetyl-CoA Delta-isomerase; COGs: COG2368 Aromatic ring hydroxylase; InterPro IPR009100:IPR004925:IPR006091:IPR013764; KEGG: chy:CHY_1730 4-hydroxyphenylacetate 3-hydroxylase family protein; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; PRIAM: Vinylacetyl-CoA Delta-isomerase; SPTR: Q3ABD4 4-hydroxyphenylacetate 3-hydroxylase family protein; PFAM: 4-hydroxyphenylacetate 3-hydroxylase N terminal; 4-hydroxyphenylacetate 3-hydroxylase C terminal. (491 aa)
Deba_1088COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR009051:IPR001041:IPR017900:IPR012675:IPR 012285:IPR017896:IPR004489; KEGG: bpt:Bpet1823 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: C1SJU7 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein. (236 aa)
Deba_1089COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterProIPR015939:IPR003953:IPR004112:IPR003952:IPR 011281:IPR014006; KEGG: apt:APA01_00330 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: C1SJU6 Succinate dehydrogenase subunit A; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgroup; su [...] (592 aa)
Deba_1090COGs: COG2142 Succinate dehydrogenase hydrophobic anchor subunit; InterPro IPR000701:IPR014312; KEGG: cts:Ctha_0457 succinate dehydrogenase, membrane subunit, putative; PFAM: succinate dehydrogenase cytochrome b subunit; SPTR: B3QUM2 Succinate dehydrogenase, membrane subunit, putative; TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein. (122 aa)
Deba_1091InterPro IPR000701:IPR014314:IPR014312; KEGG: rmr:Rmar_0208 succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; SPTR: D0MD04 Succinate dehydrogenase, cytochrome b556 subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; succinate dehydrogenase, cytochrome b556 subunit. (125 aa)
Deba_1092Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: nis:NIS_0837 fumarate/tartrate hydratase, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; SPTR: A6Q390 Fumarate/tartrate hydratase, beta subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region. (185 aa)
Deba_1093Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: dma:DMR_05730 L-tartrate dehydratase alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; PRIAM: Fumarate hydratase; SPTR: C0GM93 Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha [...] (282 aa)
Deba_1110COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR016040:IPR008927:IPR006176:IPR006108:IPR 006180:IPR013328; KEGG: dal:Dalk_2639 3-hydroxyacyl-CoA dehydrogenase NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; SPTR: B8FIU1 3-hydroxyacyl-CoA dehydrogenase NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (291 aa)
Deba_1111CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR016102:IPR016040:IPR003781; KEGG: dat:HRM2_21900 hypothetical protein; PFAM: CoA-binding domain protein; SPTR: C0QDM4 Putative uncharacterized protein; PFAM: CoA binding domain. (497 aa)
Deba_1112ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR013650:IPR011761; KEGG: dol:Dole_0137 ATP-grasp domain-containing protein; PFAM: ATP-grasp domain protein; SPTR: A8ZSN4 ATP-grasp domain protein; PFAM: ATP-grasp domain. (228 aa)
Deba_1114COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753:IPR018376; KEGG: chy:CHY_1739 putative 3-hydroxybutyryl-CoA dehydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Q3ABC5 Putative 3-hydroxybutyryl-CoA dehydratase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
Deba_1146COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR014746:IPR004809; KEGG: sat:SYN_01628 glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Q2LXX3 Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I. (443 aa)
Deba_1151Glutamate synthase, NADH/NADPH, small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR000759:IPR009051:IPR013027:IPR012285:IPR 016040:IPR006005; KEGG: mva:Mvan_5697 glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A1TH12 Glutamate synthase (NADH) small subunit; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit. (482 aa)
Deba_1152COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1528 aa)
Deba_1163COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR002933:IPR010182; KEGG: dvm:DvMF_0550 diaminopimelate aminotransferase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: B8DKS8 Peptidase M20; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (410 aa)
Deba_1177COGs: COG1045 Serine acetyltransferase; InterPro IPR011004:IPR001451; KEGG: sfu:Sfum_2682 serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM: Serine O-acetyltransferase; SPTR: A0LLQ8 Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase. (320 aa)
Deba_1178COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: dal:Dalk_2651 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: B8FIV3 Cysteine synthase A; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases. (308 aa)
Deba_11802-phosphosulfolactate phosphatase; COGs: COG2045 Phosphosulfolactate phosphohydrolase; InterPro IPR005238; KEGG: ttu:TERTU_0169 putative 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase; SPTR: C5BLF2 Putative 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (225 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
Deba_1258COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase. (886 aa)
Deba_1275COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804:IPR019818; KEGG: dol:Dole_1908 isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: A8ZSH5 Isocitrate dehydrogenase [NADP]; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (406 aa)
Deba_1293COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR016038:IPR016039; KEGG: cbe:Cbei_0411 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: A8U754 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Deba_1294COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR016038:IPR016039; KEGG: dol:Dole_2187 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: A8ZUF9 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
gpmA-2Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (271 aa)
ectCEctoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (130 aa)
Deba_1357Diaminobutyrate/2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
ectAL-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (169 aa)
Deba_1359COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR000634:IPR004450; KEGG: dal:Dalk_4397 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: B8FNA7 Threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase. (500 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (311 aa)
Deba_1368Conserved carboxylase region; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR003379:IPR013785; KEGG: dat:HRM2_31800 Pcb; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; SPTR: C0QLF7 Pcb; PFAM: HMGL-like; Conserved carboxylase domain. (502 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
Deba_1380Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (708 aa)
Deba_1382COGs: COG0460 Homoserine dehydrogenase; InterProIPR005106:IPR001342:IPR002912:IPR019811:IPR 016204:IPR016040; KEGG: gsu:GSU1693 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Q74CI0 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain. (435 aa)
Deba_1383Proposed homoserine kinase; COGs: COG3635 phosphoglycerate mutase AP superfamily; InterProIPR019304:IPR006124:IPR004456:IPR013371:IPR 017850; KEGG: pca:Pcar_1514 cofactor-independent phosphoglycerate mutase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Q3A4E7 Phosphoglycerate mutase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme superfamily; TIGRFAM: 2,3-bisphosphoglycerate-inde [...] (398 aa)
Deba_1385Pyruvate, phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR002192:IPR008279:IPR000121:IPR018274:IPR 010121:IPR013815:IPR013816:IPR015813; KEGG: gsu:GSU0580 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: Q74FM6 Pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/py [...] (894 aa)
Deba_1395COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015794:IPR015813:IPR001697:IPR 015795:IPR011037; KEGG: gau:GAU_1104 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Q1K4D5 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (474 aa)
Deba_1491COGs: COG0372 Citrate synthase; InterProIPR002020:IPR019810:IPR016142:IPR010953:IPR 016141; KEGG: dal:Dalk_4974 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: B8FDL5 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family. (429 aa)
Deba_1534COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR016038; KEGG: tac:Ta0351 acetyl-CoA acetyltransferase; SPTR: Q9HL79 Sterol carrier protein x/sterol carrier protein 2 related protein. (478 aa)
Deba_1536D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR016166:IPR016164:IPR006094:IPR004113:IPR 016167:IPR016168:IPR000542; KEGG: dat:HRM2_18570 GlcD2; PFAM: FAD linked oxidase domain protein; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: C0QBU7 GlcD2; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. (463 aa)
Deba_1537Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR009051:IPR004017:IPR012285:IPR017896:IPR 017900; KEGG: gem:GM21_0576 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C6DZR8 Putative uncharacterized protein; PFAM: Cysteine-rich domain. (393 aa)
Deba_1649Dihydropteroate synthase DHPS; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR011005:IPR000489; KEGG: dal:Dalk_4910 methionine synthase; PFAM: dihydropteroate synthase DHPS; SPTR: B8FDF5 Methionine synthase; PFAM: Pterin binding enzyme. (269 aa)
Deba_1674CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR016102:IPR016040:IPR003781; KEGG: dal:Dalk_3032 CoA-binding domain protein; PFAM: CoA-binding domain protein; SPTR: B8FL87 CoA-binding domain protein; PFAM: CoA binding domain. (489 aa)
Deba_1675ATP-grasp domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR013650:IPR011761; KEGG: dol:Dole_0137 ATP-grasp domain-containing protein; PFAM: ATP-grasp domain protein; SPTR: A8ZSN4 ATP-grasp domain protein; PFAM: ATP-grasp domain. (231 aa)
Deba_1707COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR016040:IPR008927:IPR006176:IPR006108:IPR 013328; KEGG: sth:STH2912 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; SPTR: C1XLE8 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (293 aa)
rnfBElectron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (695 aa)
Deba_1863COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR017441:IPR006176:IPR006108:IPR001753:IPR 016040:IPR008927:IPR013328; KEGG: chy:CHY_1609 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; SPTR: Q3ABP7 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (811 aa)
Deba_1864COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR002155:IPR016038; KEGG: drm:Dred_0348 acetyl-CoA acetyltransferase; SPTR: A4J1E3 3-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (301 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa)
argDCOGs: COG4992 Ornithine/acetylornithine aminotransferase; InterProIPR005814:IPR015424:IPR015422:IPR015421:IPR 004636; KEGG: sfu:Sfum_0063 acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: A0LEB4 Acetylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (398 aa)
pgiPhosphoglucose isomerase (PGI); COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: hor:Hore_19060 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: B8CZD5 Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (468 aa)
Deba_1951COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752:IPR002869; KEGG: drt:Dret_0089 pyruvate/ketoisovalerate oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: C0GP42 Pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase. (185 aa)
Deba_1952Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: gur:Gura_2238 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A5G3Q3 Thiamine pyrophosphate enzyme domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (252 aa)
Deba_1953Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR009014:IPR015941; KEGG: gme:Gmet_1307 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Q39W31 Pyruvate flavodoxin/ferredoxin oxidoreductase-like; PFAM: domain. (352 aa)
Deba_19544Fe-4S ferredoxin iron-sulfur binding domain protein; InterPro IPR017900:IPR001450:IPR017896; KEGG: dde:Dde_0043 2-oxoglutarate ferredoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q317N2 2-oxoglutarate ferredoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain. (73 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR015911:IPR001576:IPR015824:IPR015901; KEGG: gme:Gmet_1947 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Q39U98 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (413 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (422 aa)
Deba_2022COGs: COG0247 Fe-S oxidoreductase; InterPro IPR017900:IPR004017:IPR009051:IPR012285; KEGG: dae:Dtox_1734 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C8VX15 Putative uncharacterized protein; PFAM: Cysteine-rich domain. (380 aa)
Deba_2119Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR009010:IPR006656:IPR006657; KEGG: sfu:Sfum_0031 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; SPTR: A0LE82 Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (529 aa)
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (662 aa)
Deba_2131COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: sfu:Sfum_2154 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: A0LK84 Methyl-viologen-reducing hydrogenase, delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit. (141 aa)
Deba_2132FAD dependent oxidoreductase; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR016040:IPR017896:IPR017900:IPR001450:IPR 006076; KEGG: dal:Dalk_0247 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD dependent oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8FMT9 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; FAD dependent oxidoreductase. (1012 aa)
Deba_2133COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dal:Dalk_3063 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: B8FBK0 Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit. (151 aa)
Deba_2134InterPro IPR009051:IPR017896:IPR017900; KEGG: dal:Dalk_5062 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8FDV2 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. (316 aa)
Deba_2141Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterProIPR016040:IPR015884:IPR012188:IPR012301:IPR 012302:IPR002505; KEGG: glo:Glov_1262 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: B3E7A4 Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase. (751 aa)
Deba_2149COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dal:Dalk_3267 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: B8FJ30 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (290 aa)
Deba_2150FAD dependent oxidoreductase; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR013027:IPR000103:IPR016040:IPR017896:IPR 017900:IPR003953:IPR001450:IPR006076; KEGG: sfu:Sfum_3133 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: FAD dependent oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LN04 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: FAD binding domain; 4Fe-4S binding domain; FAD dependent oxidoreductase. (1011 aa)
Deba_2153COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dal:Dalk_2779 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: B8FKU9 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (307 aa)
Deba_2159Transketolase domain protein; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: sus:Acid_0656 transketolase domain-containing protein; PFAM: Transketolase domain protein; SPTR: Q02BA9 Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain. (263 aa)
Deba_2160Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR009014:IPR005475; KEGG: sus:Acid_0657 transketolase, central region; PFAM: Transketolase central region; SPTR: Q02BA8 Transketolase, central region; manually curated; PFAM: Transketolase, pyrimidine binding domain. (296 aa)
Deba_2192Aconitate hydratase; COGs: COG1048 Aconitase A; InterProIPR001030:IPR015928:IPR015931:IPR015932:IPR 000573:IPR006250; KEGG: glo:Glov_1612 aconitate hydratase; PFAM: aconitate hydratase domain protein; SPTR: Q1NKB5 Putative aconitate hydratase; TIGRFAM: aconitate hydratase; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type. (639 aa)
Deba_2198COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR016156:IPR013027:IPR000815:IPR004099:IPR 012999:IPR006258; KEGG: dsa:Desal_3027 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C6C0Y2 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (478 aa)
Deba_2224COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dol:Dole_0458 methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; SPTR: A8ZTK4 Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (307 aa)
fhsFormate--tetrahydrofolate ligase; COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR020628:IPR000559; KEGG: dat:HRM2_16700 Fhs; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: C0QAX9 Formate--tetrahydrofolate ligase; PFAM: Formate--tetrahydrofolate ligase. (590 aa)
Deba_2234Ketose-bisphosphate aldolase class-II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR013785:IPR000771; KEGG: gur:Gura_3299 fructose/tagatose bisphosphate aldolase-like protein; PFAM: ketose-bisphosphate aldolase class-II; SPTR: A5G6N8 Fructose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II. (428 aa)
Deba_2279KEGG: mta:Moth_0100 hypothetical protein; SPTR: Q2RMA0 Putative uncharacterized protein. (134 aa)
Deba_2360InterPro IPR017896:IPR017900:IPR001450; KEGG: fno:Fnod_0110 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q1K0E9 4Fe-4S ferredoxin, iron-sulfur binding. (76 aa)
Deba_2361Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR009014:IPR015941:IPR002880; KEGG: hor:Hore_06780 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: B8CVW6 3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin), alpha subunit; PFAM: domain. (366 aa)
Deba_2362Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: kol:Kole_2159 thiamine pyrophosphate protein domain protein TPP-binding; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: C5CIQ3 Thiamine pyrophosphate protein domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (248 aa)
Deba_2363COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR002869:IPR019752; KEGG: hor:Hore_06800 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: B8CVW8 3-methyl-2-oxobutanoate dehydrogenase (Ferredoxin), gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase. (185 aa)
Deba_2385COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR000276:IPR004785; KEGG: sfu:Sfum_1376 RpiB/LacA/LacB family sugar-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: A0LI15 Ribose-5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family. (148 aa)
gpmIPhosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (517 aa)
Deba_2444Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR020556:IPR000120; KEGG: dal:Dalk_0731 amidase; PFAM: Amidase; SPTR: B8FK08 Amidase; PFAM: Amidase; Belongs to the amidase family. (479 aa)
Deba_2446COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: sat:SYN_00481 glutaconyl-CoA decarboxylase A subunit; PFAM: carboxyl transferase; SPTR: Q2LUY7 Glutaconyl-CoA decarboxylase A subunit; PFAM: Carboxyl transferase domain. (576 aa)
Deba_2447COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006089:IPR013786:IPR006091:IPR013764:IPR 009100:IPR009075:IPR006092:IPR006090; KEGG: sat:SYN_00480 acyl-CoA dehydrogenase, short-chain specific; PFAM: acyl-CoA dehydrogenase domain protein; SPTR: C3UVB0 Glutaryl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (387 aa)
Deba_2449COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR016038:IPR016039; KEGG: dae:Dtox_1701 acetyl-CoA acetyltransferase; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: C8VWY2 Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Deba_2450COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR016040:IPR013328:IPR008927:IPR006176:IPR 006108; KEGG: dal:Dalk_0054 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; SPTR: B8FKE9 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (294 aa)
Deba_2451COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006089:IPR013786:IPR006091:IPR013764:IPR 009100:IPR009075:IPR006092:IPR006090; KEGG: chy:CHY_1744 acyl-CoA dehydrogenase, short-chain specific; PFAM: acyl-CoA dehydrogenase domain protein; PRIAM: Butyryl-CoA dehydrogenase; SPTR: Q3ABC0 Acyl-CoA dehydrogenase, short-chain specific; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain. (384 aa)
Deba_2503COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: mhu:Mhun_2392 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q2FT08 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (544 aa)
Deba_2621Sodium ion-translocating decarboxylase, beta subunit; COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: tga:TGAM_2029 methylmalonyl-CoA decarboxylase, beta chain (MmdB); PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; PRIAM: Oxaloacetate decarboxylase; SPTR: C5A2B2 Methylmalonyl-CoA decarboxylase, beta chain (MmdB); TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit. (401 aa)
Deba_2692COGs: COG1254 Acylphosphatase; InterPro IPR017968:IPR001792; KEGG: ade:Adeh_0694 acylphosphatase; PFAM: acylphosphatase; SPTR: Q2INT8 Acylphosphatase; PFAM: Acylphosphatase. (92 aa)
Deba_2695Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; COGs: COG1109 Phosphomannomutase; InterProIPR016066:IPR016055:IPR005844:IPR005845:IPR 005846:IPR005843:IPR005841; KEGG: sfu:Sfum_0481 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase; SPTR: A0LFH9 Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...] (451 aa)
Deba_2710Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303:IPR014710:IPR011051:IPR013096; KEGG: chl:Chy400_0637 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; Cupin 2 conserved barrel domain protein; SPTR: B9LJP0 Class II aldolase/adducin family protein; PFAM: Cupin domain; Class II Aldolase and Adducin N-terminal domain. (355 aa)
Deba_2756CoA-binding domain protein; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterProIPR003781:IPR013650:IPR016102:IPR011761:IPR 016040; KEGG: dal:Dalk_0366 CoA-binding domain protein; PFAM: CoA-binding domain protein; ATP-grasp domain protein; SPTR: B8FGY7 CoA-binding domain protein; PFAM: CoA binding domain. (709 aa)
Deba_2842Molybdopterin oxidoreductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006963:IPR006656:IPR006657:IPR009010:IPR 006655; KEGG: dvl:Dvul_2794 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Q1NQN8 Formate dehydrogenase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (713 aa)
Deba_2849COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752:IPR002869; KEGG: sfu:Sfum_1168 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: A0LHF9 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase. (202 aa)
Deba_28502-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sfu:Sfum_1167 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: A0LHF8 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (283 aa)
Deba_2851Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR015941:IPR009014:IPR005829; KEGG: sfu:Sfum_1166 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: A0LHF7 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: domain. (378 aa)
Deba_2852InterPro IPR001450:IPR017896:IPR017900; KEGG: sfu:Sfum_1165 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LHF6 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (108 aa)
Deba_2958Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731:IPR013785; KEGG: dol:Dole_1224 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: A8ZY23 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (327 aa)
Deba_2981COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR004099:IPR000815:IPR016156:IPR 012999:IPR006258; KEGG: mta:Moth_1763 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: A1HU83 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (456 aa)
Deba_2985Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR001450:IPR004017:IPR012285:IPR017896:IPR 009051:IPR017900; KEGG: mac:MA0688 heterodisulfide reductase, subunit D; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Q8TSV7 CoB--CoM heterodisulfide reductase 2 iron-sulfur subunit D; PFAM: Cysteine-rich domain. (399 aa)
Deba_3064Pyruvate, water dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR008279:IPR002192:IPR013815; KEGG: sfu:Sfum_2666 pyruvate, water dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PRIAM: Pyruvate, water dikinase; SPTR: A0LLP2 Phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain. (876 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
Deba_3073COGs: COG2191 Formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: mtp:Mthe_1665 formylmethanofuran dehydrogenase, subunit E region; PFAM: formylmethanofuran dehydrogenase subunit E region; SPTR: A0B9Q7 Formylmethanofuran dehydrogenase, subunit E region; PFAM: Prokaryotic dksA/traR C4-type zinc finger; FmdE, Molybdenum formylmethanofuran dehydrogenase operon. (185 aa)
Deba_3094AMP-dependent synthetase and ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: scl:sce8601 CapK related-protein; PFAM: AMP-dependent synthetase and ligase; SPTR: A9FZN1 CapK related-protein; PFAM: AMP-binding enzyme. (453 aa)
Deba_3132Propanoyl-CoA C-acyltransferase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR016039:IPR002155:IPR016038; KEGG: dal:Dalk_3190 acetyl-CoA acetyltransferase; PRIAM: Propanoyl-CoA C-acyltransferase; SPTR: B8FGH1 Propanoyl-CoA C-acyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
Deba_31806-phosphogluconate dehydrogenase, decarboxylating; COGs: COG1023 6-phosphogluconate dehydrogenase; InterProIPR004849:IPR016040:IPR008927:IPR006115:IPR 006114:IPR006183:IPR013328:IPR016059:IPR002204; KEGG: dma:DMR_05560 putative 6-phosphogluconate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; SPTR: C4XI85 Putative 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain [...] (303 aa)
acsA-2acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (665 aa)
Deba_3201Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sfu:Sfum_2795 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0LM21 Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. (320 aa)
Deba_3202Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR009014:IPR002880:IPR015941; KEGG: sfu:Sfum_2794 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: A0LM20 Pyruvate ferredoxin oxidoreductase, alpha subunit; PFAM: domain. (391 aa)
Deba_3203COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898:IPR001450:IPR017896:IPR017900; KEGG: sfu:Sfum_2793 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LM19 Pyruvate ferredoxin oxidoreductase, delta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family. (109 aa)
Deba_3204Pyruvate/ketoisovalerate oxidoreductase, gamma subunit; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR011894:IPR002869:IPR019752; KEGG: sat:SYN_00157 pyruvate:ferredoxin oxidoreductase gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: Q2LYF2 Pyruvate:ferredoxin oxidoreductase gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate [...] (182 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (205 aa)
Deba_3254Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR016185:IPR011054:IPR005481:IPR005479:IPR 005482:IPR011761:IPR011764:IPR013817:IPR013816; KEGG: dol:Dole_2179 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: A8ZUF1 Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-term [...] (495 aa)
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (24%) [HD]