STRINGSTRING
Arch_0849 Arch_0849 gmk gmk Arch_0871 Arch_0871 cmk cmk tpiA tpiA pgk pgk Arch_0884 Arch_0884 coaE coaE aln aln nadK nadK Arch_0943 Arch_0943 Arch_1077 Arch_1077 thiL thiL Arch_1123 Arch_1123 Arch_1131 Arch_1131 Arch_1164 Arch_1164 Arch_1229 Arch_1229 Arch_1278 Arch_1278 thiM thiM Arch_1283 Arch_1283 pgi pgi Arch_1291 Arch_1291 ackA ackA coaA coaA Arch_1345 Arch_1345 adk adk udk udk Arch_1407 Arch_1407 Arch_1418 Arch_1418 Arch_1428 Arch_1428 ldh ldh Arch_1458 Arch_1458 Arch_1460 Arch_1460 Arch_1502 Arch_1502 eno eno prs prs ispE ispE Arch_1588 Arch_1588 Arch_1589 Arch_1589 Arch_1603 Arch_1603 Arch_1627 Arch_1627 Arch_1642 Arch_1642 Arch_1644 Arch_1644 Arch_1665 Arch_1665 gpmA gpmA tmk tmk rbsK rbsK Arch_1751 Arch_1751 Arch_1809 Arch_1809 Arch_0036 Arch_0036 Arch_0045 Arch_0045 Arch_0046 Arch_0046 Arch_0056 Arch_0056 Arch_0102 Arch_0102 Arch_0192 Arch_0192 Arch_0240 Arch_0240 Arch_0254 Arch_0254 glpK glpK Arch_0264 Arch_0264 Arch_0330 Arch_0330 Arch_0352 Arch_0352 Arch_0384 Arch_0384 Arch_0411 Arch_0411 Arch_0416 Arch_0416 Arch_0437 Arch_0437 Arch_0470 Arch_0470 Arch_0491 Arch_0491 Arch_0527 Arch_0527 Arch_0530 Arch_0530 Arch_0899 Arch_0899 Arch_0555 Arch_0555 Arch_0556 Arch_0556 pyrH pyrH Arch_0626 Arch_0626 Arch_0642 Arch_0642 Arch_0715 Arch_0715 Arch_0718 Arch_0718 Arch_0726 Arch_0726 Arch_0731 Arch_0731 Arch_0735 Arch_0735 Arch_0012 Arch_0012 pfp pfp Arch_0754 Arch_0754 Arch_0756 Arch_0756 Arch_0769 Arch_0769 Arch_0828 Arch_0828 aroK aroK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Arch_0849KEGG: fal:FRAAL5246 shikimate kinase; SPTR: Q0RF71 Shikimate kinase I; PFAM: Shikimate kinase. (183 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (190 aa)
Arch_0871COGs: COG1716 FOG: FHA domain; InterPro IPR008984:IPR000253; KEGG: bcv:Bcav_2102 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: D0WMV9 GarA protein; PFAM: FHA domain. (150 aa)
cmkCOGs: COG0283 Cytidylate kinase; InterPro IPR003136:IPR000623:IPR011994; KEGG: jde:Jden_1271 cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; SPTR: D0WMU4 Prephenate dehydrogenase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase. (231 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015911:IPR015824:IPR015901; KEGG: jde:Jden_1257 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: D0WMT2 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)
Arch_0884COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020832:IPR016040:IPR020830:IPR020831:IPR 006424:IPR020828:IPR020829; KEGG: cdi:DIP1310 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Q6NH35 Glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, [...] (335 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (281 aa)
alnThiol-activated cytolysin; InterPro IPR001869; KEGG: ssb:SSUBM407_0558 suilysin (hemolysin); PFAM: Thiol-activated cytolysin; SPTR: O31241 Pyolysin; PFAM: Thiol-activated cytolysin. (569 aa)
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (293 aa)
Arch_0943Thiamin pyrophosphokinase catalytic region; COGs: COG4825 Uncharacterized membrane-anchored protein; InterPro IPR007371; KEGG: bcv:Bcav_2354 thiamin pyrophosphokinase catalytic region; PFAM: Thiamin pyrophosphokinase catalytic region; SPTR: D0WMI8 Thiamin pyrophosphokinase, catalytic domain protein; PFAM: Thiamine pyrophosphokinase C terminal; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase. (403 aa)
Arch_1077COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR003018:IPR011712; KEGG: bcv:Bcav_1613 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: GAF domain protein; ATP-binding region ATPase domain protein; SPTR: D0WNC3 Putative two-component sensor; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain. (544 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (324 aa)
Arch_1123Dihydroxyacetone kinase, DhaK subunit; COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004007:IPR012736:IPR012737:IPR004006; KEGG: msm:MSMEG_2123 dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase; Dak phosphatase; PRIAM: Glycerone kinase; SPTR: A0QU93 Dihydroxyacetone kinase, DhaK subunit; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; dihydroxyacetone kinase, L subunit; PFAM: DAK2 domain; Dak1 domain; TIGRFAM: dihydroxyacetone kinase, ATP-dependent; dihydroxyacetone kinase, DhaK subunit; dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. (580 aa)
Arch_1131Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003594:IPR009082:IPR005467:IPR003661:IPR 004358; KEGG: xce:Xcel_2991 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: D1BZA0 Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (266 aa)
Arch_1164Galactokinase; COGs: COG0153 Galactokinase; InterProIPR020568:IPR000705:IPR019741:IPR006203:IPR 014721:IPR019539:IPR006204:IPR013750:IPR006206; KEGG: nca:Noca_2607 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: A1SJX6 Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily. (378 aa)
Arch_1229COGs: COG3173 aminoglycoside phosphotransferase; InterPro IPR011009:IPR002575; KEGG: bcv:Bcav_2900 aminoglycoside phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: D0WNM2 Putative phosphotransferase; PFAM: Phosphotransferase enzyme family. (339 aa)
Arch_1278Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004305:IPR016084:IPR004399; KEGG: pac:PPA0110 thiamine-phosphate pyrophosphorylase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain protein; SPTR: Q6ABQ9 Putative thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TENA/THI-4/PQQC family; TIGRFAM: phosphomethylpyrimidine kinase. (537 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (267 aa)
Arch_1283COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: bcv:Bcav_3034 putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: C0W6Q0 Signal transduction histidine kinase; PFAM: PspC domain. (406 aa)
pgiCOGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: pac:PPA2131 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: D0WNS5 Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family. (552 aa)
Arch_12916-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (764 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (390 aa)
coaACOGs: COG1072 Panthothenate kinase; InterPro IPR004566; KEGG: xce:Xcel_0666 pantothenate kinase; SPTR: A7B9K0 Putative uncharacterized protein; TIGRFAM: pantothenate kinase; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: pantothenate kinase, bacterial type. (313 aa)
Arch_1345ROK family protein; InterPro IPR000600; KEGG: xce:Xcel_0657 ROK family protein; PFAM: ROK family protein; SPTR: D0WP77 ROK protein; manually curated; PFAM: ROK family. (265 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (194 aa)
udkCOGs: COG0572 Uridine kinase; InterPro IPR006083:IPR000764:IPR017975; KEGG: cbt:CLH_0992 uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SPTR: D0WPE8 Uridine kinase; TIGRFAM: uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: uridine kinase. (207 aa)
Arch_1407InterPro IPR002575:IPR011009; KEGG: jde:Jden_2348 aminoglycoside phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: D0WPG1 Phosphotransferase enzyme family protein; PFAM: Phosphotransferase enzyme family. (419 aa)
Arch_1418COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003661:IPR003594:IPR 009082:IPR004358; KEGG: bcv:Bcav_1241 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: D0WPH4 Sensor histidine kinase MtrB; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (554 aa)
Arch_1428COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003661:IPR003594:IPR 009082:IPR004358; KEGG: bcv:Bcav_1156 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: D0WPL5 Putative two-component system histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (438 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (318 aa)
Arch_1458PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...] (659 aa)
Arch_1460Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (566 aa)
Arch_1502PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: kra:Krad_1118 PfkB domain protein; PFAM: PfkB domain protein; SPTR: A6W717 PfkB domain protein; PFAM: pfkB family carbohydrate kinase. (315 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (342 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (316 aa)
Arch_1588PTS system, glucose subfamily, IIA subunit; COGs: COG2190 Phosphotransferase system IIA components; InterPro IPR001127:IPR011055; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component. (161 aa)
Arch_1589PTS system, N-acetylglucosamine-specific IIBC subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR003352:IPR018113:IPR 010974:IPR011535; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosph [...] (531 aa)
Arch_1603COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: kse:Ksed_01000 signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: C2BTB8 Two component system histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (359 aa)
Arch_1627COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR009082:IPR 005467:IPR004358; KEGG: kra:Krad_3621 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: D0WJT8 PhoR protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoaccept [...] (509 aa)
Arch_1642COGs: COG0515 Serine/threonine protein kinase; InterProIPR017441:IPR008271:IPR020635:IPR002290:IPR 011009:IPR000719:IPR017442; KEGG: bcv:Bcav_0797 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: D0WJV4 Putative tyrosine protein kinase:Serine/threonine protein kinase; PFAM: Protein kinase domain. (543 aa)
Arch_1644KEGG: bcv:Bcav_0782 hypothetical protein; SPTR: C0VYH1 Putative uncharacterized protein; PFAM: Lipopolysaccharide kinase (Kdo/WaaP) family. (435 aa)
Arch_1665Histidine kinase; COGs: COG5002 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR009082:IPR005467:IPR 004358; KEGG: bcv:Bcav_0770 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C5BYS3 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (393 aa)
gpmAPhosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (246 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (219 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (300 aa)
Arch_1751Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: bcv:Bcav_0378 diacylglycerol kinase catalytic region; PFAM: diacylglycerol kinase catalytic region; SPTR: D0WKA0 Putative diacylglycerol kinase catalytic domain protein; PFAM: Diacylglycerol kinase catalytic domain. (386 aa)
Arch_1809Hypothetical protein; InterPro IPR011009; KEGG: xce:Xcel_3367 hypothetical protein; SPTR: D1BRV0 Putative uncharacterized protein. (662 aa)
Arch_0036PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: bcv:Bcav_1099 fructokinase; PFAM: PfkB domain protein; SPTR: C1RNV6 Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase. (316 aa)
Arch_0045PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002139; KEGG: rer:RER_20210 5-dehydro-2-deoxygluconokinase; PFAM: PfkB domain protein; SPTR: C0W6K8 Possible 5-dehydro-2-deoxygluconokinase; PFAM: pfkB family carbohydrate kinase. (329 aa)
Arch_0046KEGG: sro:Sros_5538 hypothetical protein; SPTR: D0YPL4 Deoxyribose-phosphate aldolase superfamily protein. (287 aa)
Arch_0056ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: pac:PPA2359 putative transcriptional repressor protein; PFAM: ROK family protein; SPTR: Q6A633 Putative transcriptional repressor protein; PFAM: ROK family. (300 aa)
Arch_0102COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR005543:IPR017442:IPR 005503:IPR000719:IPR011009:IPR017441:IPR008271; KEGG: xce:Xcel_0018 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; flagellar basal body-associated protein FliL; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA domain containing protein; SPTR: D0WKX3 Putative serine/threonine protein kinase; PFAM: Protein kinase domain; PASTA domain. (633 aa)
Arch_0192Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
Arch_0240Pyruvate, phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR002192:IPR008279:IPR000121:IPR013815:IPR 013816:IPR015813:IPR010121:IPR018274; KEGG: tfu:Tfu_0863 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: D0WM96 Pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/ [...] (912 aa)
Arch_02542-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (291 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (507 aa)
Arch_0264ATP-binding protein; COGs: COG0572 Uridine kinase; KEGG: bcv:Bcav_3297 ATP-binding protein; SPTR: C5C1D0 ATP-binding protein. (220 aa)
Arch_0330ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: bln:Blon_0644 ROK family protein; PFAM: ROK family protein; SPTR: A7BBZ4 Putative uncharacterized protein; PFAM: ROK family. (305 aa)
Arch_0352COGs: COG0083 Homoserine kinase; InterPro IPR014721:IPR020568; KEGG: cai:Caci_1201 homoserine kinase; SPTR: D0WRS3 Homoserine kinase. (275 aa)
Arch_0384Aminoglycoside phosphotransferase; COGs: COG3281 Uncharacterized protein probably involved in trehalose biosynthesis; InterPro IPR002160:IPR002575:IPR011009; KEGG: cmi:CMM_2112 putative phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: D0WRV4 Pep2 protein; PFAM: Phosphotransferase enzyme family. (459 aa)
Arch_0411COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR013656:IPR011495; KEGG: bcv:Bcav_2829 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: D0WS29 Sensor histidine kinase; PFAM: Histidine kinase; Signal transduction histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. (474 aa)
Arch_0416COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: bcv:Bcav_2821 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: D0WS36 Putative signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (396 aa)
Arch_0437PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: xce:Xcel_0908 PfkB domain protein; PFAM: PfkB domain protein; SPTR: D0YQL2 Carbohydrate kinase; PFAM: pfkB family carbohydrate kinase. (366 aa)
Arch_0470InterPro IPR001996; KEGG: cai:Caci_8113 phosphotransferase system PTS EIIB protein; SPTR: C7QIN6 Phosphotransferase system PTS EIIB protein. (79 aa)
Arch_0491COGs: COG1428 Deoxynucleoside kinase; InterPro IPR002624; KEGG: cbt:CLH_1831 deoxyguanosIne kinase; PFAM: deoxynucleoside kinase; SPTR: A8U7A9 Deoxynucleoside kinase family protein; PFAM: Deoxynucleoside kinase. (222 aa)
Arch_0527COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: cai:Caci_0638 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: C2KNP1 Histidine kinase. (376 aa)
Arch_0530Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: kse:Ksed_07210 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SPTR: D0WNH3 Sensor histidine kinase; manually curated; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (242 aa)
Arch_0899COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015813:IPR015795:IPR011037:IPR 018209:IPR015794:IPR001697; KEGG: bcv:Bcav_2215 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: D0WMQ1 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (472 aa)
Arch_0555COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: krh:KRH_11260 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: C0W772 Nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family. (138 aa)
Arch_0556Dihydroxyacetone kinase, L subunit; COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004007:IPR012737; KEGG: car:cauri_1454 dihydroxyacetone kinase; PFAM: Dak phosphatase; SPTR: A7BCU2 Putative uncharacterized protein; TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: DAK2 domain; TIGRFAM: dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. (202 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa)
Arch_0626Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR014729:IPR015865:IPR015864:IPR002606; KEGG: bcv:Bcav_2486 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; SPTR: D0WR17 Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (331 aa)
Arch_0642Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003594:IPR009082:IPR003661:IPR 005467; KEGG: xce:Xcel_2991 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C2KNB8 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (257 aa)
Arch_0715Haloacid dehalogenase domain protein hydrolase; COGs: COG0546 phosphatase; InterPro IPR005834; KEGG: rer:RER_36620 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: D0WQQ9 Phosphatase, HAD family; PFAM: haloacid dehalogenase-like hydrolase. (237 aa)
Arch_07182-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (917 aa)
Arch_0726Polyphosphate--glucose phosphotransferase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: xce:Xcel_2049 ROK family protein; PFAM: ROK family protein; PRIAM: Polyphosphate--glucose phosphotransferase; SPTR: D1BFU6 Polyphosphate glucokinase; PFAM: ROK family. (256 aa)
Arch_0731Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR001345:IPR013078; KEGG: aau:AAur_3898 phosphoglycerate mutase family protein; PFAM: Phosphoglycerate mutase; SPTR: A1RBG3 Phosphoglycerate mutase family protein; PFAM: Phosphoglycerate mutase family. (200 aa)
Arch_0735COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR011053:IPR004167:IPR003016:IPR000089:IPR 014276:IPR001078; KEGG: rmu:RMDY18_07280 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: A7BC68 Putative uncharacterized protein; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: [...] (564 aa)
Arch_0012Aminoglycoside phosphotransferase; InterPro IPR002575:IPR011009; KEGG: blj:BLD_1766 putative homoserine kinase type II; PFAM: aminoglycoside phosphotransferase; SPTR: A7BJ81 N-acetylhexosamine kinase; PFAM: Phosphotransferase enzyme family. (358 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (406 aa)
Arch_0754Serine/threonine protein kinase with PASTA sensor(s); COGs: COG2815 conserved hypothetical protein; InterProIPR011009:IPR008271:IPR020635:IPR002290:IPR 005543:IPR000719:IPR017442; KEGG: bcv:Bcav_1908 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA domain containing protein; SPTR: A7BDG0 Putative uncharacterized protein; PFAM: Protein kinase domain; PASTA domain. (641 aa)
Arch_0756KEGG: bcv:Bcav_1909 hypothetical protein; SPTR: D0WQK7 Putative transcriptional regulatory protein. (120 aa)
Arch_0769COGs: COG1435 Thymidine kinase; InterPro IPR001267; KEGG: bcv:Bcav_1932 thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase; SPTR: D0WQI6 Thymidine kinase; PFAM: Thymidine kinase. (215 aa)
Arch_0828(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (772 aa)
aroK3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (515 aa)
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (18%) [HD]