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nusB nusB efp efp Arch_0820 Arch_0820 sigA sigA Arch_0749 Arch_0749 Arch_0736 Arch_0736 Arch_0730 Arch_0730 Arch_0688 Arch_0688 Arch_0678 Arch_0678 mraZ mraZ nrdR nrdR lexA lexA recX recX Arch_0642 Arch_0642 Arch_0641 Arch_0641 infB infB nusA nusA tsf tsf Arch_0544 Arch_0544 Arch_0530 Arch_0530 Arch_0529 Arch_0529 Arch_0527 Arch_0527 Arch_0526 Arch_0526 Arch_0490 Arch_0490 Arch_0478 Arch_0478 Arch_0467 Arch_0467 Arch_0466 Arch_0466 Arch_0452 Arch_0452 Arch_0435 Arch_0435 Arch_0416 Arch_0416 Arch_0415 Arch_0415 whiB whiB Arch_0403 Arch_0403 Arch_0401 Arch_0401 Arch_0378 Arch_0378 Arch_0376 Arch_0376 Arch_0371 Arch_0371 prfA prfA Arch_0336 Arch_0336 Arch_0335 Arch_0335 Arch_0334 Arch_0334 Arch_0329 Arch_0329 Arch_0324 Arch_0324 Arch_0321 Arch_0321 Arch_0315 Arch_0315 Arch_0311 Arch_0311 Arch_0282 Arch_0282 Arch_0280 Arch_0280 Arch_0279 Arch_0279 Arch_0268 Arch_0268 Arch_0171 Arch_0171 Arch_0146 Arch_0146 Arch_0130 Arch_0130 Arch_0115 Arch_0115 Arch_0109 Arch_0109 Arch_0044 Arch_0044 Arch_0035 Arch_0035 Arch_0009 Arch_0009 dnaA dnaA Arch_0859 Arch_0859 Arch_1767 Arch_1767 Arch_1749 Arch_1749 Arch_1733 Arch_1733 whiB-4 whiB-4 Arch_1722 Arch_1722 Arch_1675 Arch_1675 Arch_1671 Arch_1671 Arch_1670 Arch_1670 Arch_1666 Arch_1666 Arch_1665 Arch_1665 Arch_1664 Arch_1664 Arch_1635 Arch_1635 Arch_1627 Arch_1627 Arch_1626 Arch_1626 Arch_1622 Arch_1622 Arch_1618 Arch_1618 Arch_1604 Arch_1604 Arch_1603 Arch_1603 Arch_1590 Arch_1590 Arch_1585 Arch_1585 Arch_1581 Arch_1581 Arch_1557 Arch_1557 Arch_1551 Arch_1551 mfd mfd greA greA Arch_1488 Arch_1488 Arch_1483 Arch_1483 Arch_1478 Arch_1478 Arch_1459 Arch_1459 Arch_1437 Arch_1437 Arch_1430 Arch_1430 Arch_1429 Arch_1429 Arch_1428 Arch_1428 whiB-3 whiB-3 Arch_1419 Arch_1419 Arch_1418 Arch_1418 hpf hpf nusG nusG rplA rplA Arch_1394 Arch_1394 fusA fusA tuf tuf infA infA whiB-2 whiB-2 Arch_1282 Arch_1282 Arch_1260 Arch_1260 Arch_1235 Arch_1235 Arch_1224 Arch_1224 prfB prfB Arch_1197 Arch_1197 Arch_1191 Arch_1191 Arch_1189 Arch_1189 Arch_1187 Arch_1187 Arch_1180 Arch_1180 Arch_1149 Arch_1149 Arch_1131 Arch_1131 Arch_1130 Arch_1130 Arch_1095 Arch_1095 Arch_1078 Arch_1078 Arch_1077 Arch_1077 Arch_1076 Arch_1076 Arch_1067 Arch_1067 rsfS rsfS Arch_1056 Arch_1056 lepA lepA hrcA hrcA infC infC argR argR Arch_0938 Arch_0938 Arch_0929 Arch_0929 Arch_0922 Arch_0922 Arch_0898 Arch_0898 Arch_0887 Arch_0887 Arch_0871 Arch_0871 Arch_0870 Arch_0870 Arch_0869 Arch_0869 rbpA rbpA Arch_0865 Arch_0865 Arch_0864 Arch_0864
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proteins of unknown 3D structure
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nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (159 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa)
Arch_0820Protein of unknown function DUF28; COGs: COG0217 conserved hypothetical protein; InterPro IPR002876:IPR017856; KEGG: ami:Amir_2110 protein of unknown function DUF28; PFAM: protein of unknown function DUF28; SPTR: D0WQF1 Protein YebC; PFAM: Domain of unknown function DUF28; TIGRFAM: conserved hypothetical protein TIGR01033. (254 aa)
sigARNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (510 aa)
Arch_0749InterPro IPR011006:IPR001789; KEGG: bcv:Bcav_1893 response regulator receiver protein; SPTR: D0WQL5 Two-component system response regulator. (131 aa)
Arch_0736COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000815:IPR016156:IPR012999:IPR 004099:IPR006258; KEGG: jde:Jden_1475 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: D0WQM8 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase. (458 aa)
Arch_0730(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] (937 aa)
Arch_0688Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: bcv:Bcav_1772 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: C5C4Q0 Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (132 aa)
Arch_0678Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: tfu:Tfu_1114 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Q47QW5 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726. (256 aa)
mraZMraZ protein; COGs: COG2001 conserved hypothetical protein; InterPro IPR003444:IPR020603; KEGG: krh:KRH_14910 cell division protein MraZ; PFAM: MraZ domain; SPTR: D0WQW6 MraZ protein; TIGRFAM: MraZ protein; PFAM: MraZ protein; TIGRFAM: mraZ protein; Belongs to the MraZ family. (143 aa)
nrdRATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (167 aa)
lexATranscriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (262 aa)
recXRegulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. (195 aa)
Arch_0642Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003594:IPR009082:IPR003661:IPR 005467; KEGG: xce:Xcel_2991 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C2KNB8 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (257 aa)
Arch_0641Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR011991:IPR001867; KEGG: xce:Xcel_2992 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D1BZA1 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (228 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (971 aa)
nusATranscription termination factor NusA; Participates in both transcription termination and antitermination. (325 aa)
tsfTranslation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (288 aa)
Arch_0544Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR013838:IPR000843:IPR001761:IPR010982; KEGG: rop:ROP_52910 putative LacI family transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: A7BCA6 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family. (331 aa)
Arch_0530Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: kse:Ksed_07210 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SPTR: D0WNH3 Sensor histidine kinase; manually curated; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (242 aa)
Arch_0529Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR000792:IPR001789:IPR011006:IPR 016032; KEGG: ckp:ckrop_0504 two-component system, response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WNH1 Two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (225 aa)
Arch_0527COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: cai:Caci_0638 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: C2KNP1 Histidine kinase. (376 aa)
Arch_0526Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR001789:IPR013249:IPR000792:IPR 011006; KEGG: kra:Krad_4263 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; SPTR: D0YQC0 Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (219 aa)
Arch_0490InterPro IPR011991:IPR001845; KEGG: cms:CMS_0559 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: B0RD80 Putative ArsR-family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family. (99 aa)
Arch_0478Protein of unknown function UPF0029; COGs: COG1739 conserved hypothetical protein; InterPro IPR020569:IPR001498:IPR015269:IPR020568; KEGG: cur:cur_1185 hypothetical protein; PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; SPTR: D0WRC8 IMPACT family member YigZ; PFAM: Uncharacterized protein family UPF0029; TIGRFAM: conserved hypothetical protein TIGR00257. (217 aa)
Arch_0467Addiction module toxin, Txe/YoeB family; COGs: COG4115 conserved hypothetical protein; InterPro IPR009614; KEGG: dhd:Dhaf_2026 addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB; SPTR: C4G508 Putative uncharacterized protein; TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family. (89 aa)
Arch_0466InterPro IPR007337; KEGG: lba:Lebu_0151 addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; SPTR: C7ND10 Addiction module antitoxin, RelB/DinJ family; TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family. (86 aa)
Arch_0452COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR017871:IPR003439:IPR003593; KEGG: mlu:Mlut_09750 ATPase component of ABC transporters with duplicated ATPase domain; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: D0WRE3 ABC transporter, ATP-binding protein; PFAM: ABC transporter. (560 aa)
Arch_0435Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: pac:PPA2330 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: D0YQM2 LacI family transcription regulator; PFAM: Bacterial regulatory proteins, lacI family; family. (335 aa)
Arch_0416COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: bcv:Bcav_2821 histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: D0WS36 Putative signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (396 aa)
Arch_0415Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR000792:IPR001789:IPR011006:IPR 016032; KEGG: bcv:Bcav_2822 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WS35 Two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (230 aa)
whiBTranscription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (82 aa)
Arch_0403InterPro IPR011991:IPR005149; KEGG: art:Arth_0527 PadR family transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: C2KN54 PadR family transcriptional regulator; PFAM: Transcriptional regulator PadR-like family. (182 aa)
Arch_0401Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR011991:IPR000524; KEGG: kse:Ksed_02920 predicted transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: D0WP12 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family. (129 aa)
Arch_0378Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: sro:Sros_3351 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: D0WRV0 HTH-type transcriptional regulator MalR; PFAM: Bacterial regulatory proteins, lacI family; family. (336 aa)
Arch_0376COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR012335:IPR012336; KEGG: bcv:Bcav_1333 thioredoxin domain protein; SPTR: D0WRU8 Thioredoxin-related protein; PFAM: Thioredoxin. (310 aa)
Arch_0371KEGG: cai:Caci_1238 hypothetical protein; SPTR: D0WRU2 Putative ATP/GTP-binding protein, doubtful CDS. (95 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (370 aa)
Arch_0336COGs: COG4877 conserved hypothetical protein; KEGG: ami:Amir_1210 hypothetical protein; SPTR: C6WRB0 Putative uncharacterized protein. (71 aa)
Arch_0335Anti-sigma factor; InterPro IPR014295; KEGG: cdi:DIP0710 putative anti sigma factor; SPTR: D0WRQ3 Anti-sigma factor RshA; TIGRFAM: anti-sigma factor; TIGRFAM: anti-sigma factor, TIGR02949 family. (93 aa)
Arch_0334RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterProIPR000838:IPR007627:IPR013249:IPR014293:IPR 014284:IPR013325:IPR013324; KEGG: bcv:Bcav_1265 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: D0WRQ2 RNA polymerase sigma-70 factor; TIGRFAM: RNA polymerase sigma-70 factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymer [...] (201 aa)
Arch_0329Regulatory protein GntR HTH; COGs: COG2186 Transcriptional regulators; InterPro IPR011991:IPR000524:IPR011711; KEGG: bcv:Bcav_3776 regulatory protein GntR HTH; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: D0WKM6 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain. (267 aa)
Arch_0324KEGG: mpa:MAP0512c hypothetical protein; SPTR: Q743S9 Putative uncharacterized protein. (210 aa)
Arch_0321KEGG: cdi:DIP2121 hypothetical protein; SPTR: D0WPQ4 PAS/PAC domain protein; TIGRFAM: PAS domain S-box. (479 aa)
Arch_0315InterPro IPR000551:IPR010093:IPR009061; KEGG: jde:Jden_1818 DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; SPTR: D0WRN3 DNA binding domain, excisionase family protein; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family. (70 aa)
Arch_0311KEGG: mtc:MT2002 hypothetical protein; SPTR: Q8VJT9 Putative uncharacterized protein. (78 aa)
Arch_0282KEGG: xce:Xcel_0448 hypothetical protein; SPTR: D0WMF2 Putative membrane protein. (131 aa)
Arch_0280InterPro IPR000835:IPR011991; KEGG: bcv:Bcav_3256 transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: D1BBA8 Transcriptional regulator, MarR family; PFAM: MarR family. (158 aa)
Arch_0279DNA binding domain protein, excisionase family; InterPro IPR010093:IPR009061:IPR000843; KEGG: bcv:Bcav_3263 excision promoter, Xis; SPTR: D0WME4 Putative excisionase; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family. (71 aa)
Arch_0268Transcriptional regulator, DeoR family; COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324:IPR009057; KEGG: bcv:Bcav_3288 transcriptional regulator, DeoR family; PFAM: putative sugar-binding domain protein; SPTR: D0YR88 Sugar-binding family transcriptional regulator; PFAM: Sigma-70, region 4; Putative sugar-binding domain. (316 aa)
Arch_0171Transcriptional regulator, MerR family; InterPro IPR000551:IPR009061; KEGG: bfa:Bfae_12190 predicted transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: D0WLG6 Heat shock regulator protein HspR; PFAM: MerR family regulatory protein. (214 aa)
Arch_0146Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367:IPR007167:IPR011991:IPR008988; KEGG: bfa:Bfae_31300 Mn-dependent transcriptional regulator; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; SPTR: C7MB03 Mn-dependent transcriptional regulator; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain. (225 aa)
Arch_0130Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: mva:Mvan_4015 UbiC transcription regulator-associated domain-containing protein; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: A7BEH3 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. (251 aa)
Arch_0115Glutaredoxin-like protein NrdH; COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109:IPR012335:IPR011909:IPR012336; KEGG: bcv:Bcav_0095 glutaredoxin-like protein NrdH; PFAM: glutaredoxin; SPTR: D0WKQ6 Glutaredoxin; TIGRFAM: glutaredoxin-like protein NrdH; PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein NrdH. (83 aa)
Arch_0109Appr-1-p processing domain protein; COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: sse:Ssed_1314 hypothetical protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: D0WKT6 Appr-1-p processing enzyme family domain protein; PFAM: Macro domain. (302 aa)
Arch_0044Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: msm:MSMEG_4659 GntR-family protein transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: C2KTD8 Transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. (258 aa)
Arch_0035Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761:IPR010982; KEGG: pac:PPA1457 LacI family transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Q6A7R0 Putative LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family. (342 aa)
Arch_0009COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: cef:CE2684 hypothetical protein; PFAM: AAA-4 family protein; SPTR: C0VWZ2 Transcriptional regulator; PFAM: Divergent AAA domain. (578 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (544 aa)
Arch_0859Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: jde:Jden_1312 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: D0WMY6 Ribosomal RNA small subunit methyltransferase B; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (484 aa)
Arch_1767Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: ami:Amir_0404 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: C6WGQ5 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. (227 aa)
Arch_1749Transcriptional regulator, LuxR family; InterPro IPR000792:IPR016032:IPR011991; KEGG: sco:SCO1353 transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Q7WWP4 Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, luxR family. (308 aa)
Arch_1733Transcriptional regulator, DeoR family; COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR009057:IPR007324; KEGG: krh:KRH_18930 deoxyribonucleoside regulator; PFAM: putative sugar-binding domain protein; SPTR: C0W0V8 DeoR family transcriptional regulator; PFAM: Putative sugar-binding domain. (313 aa)
whiB-4Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (106 aa)
Arch_1722Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001808:IPR018490:IPR012318:IPR 014710:IPR011991; KEGG: sgr:SGR_3333 Crp/Fnr family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: D0WK55 Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. (225 aa)
Arch_1675InterPro IPR001845:IPR011991; KEGG: nml:Namu_2556 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: C8X7G0 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (102 aa)
Arch_1671Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: cdi:DIP1749 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Q6NFY6 Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937. (84 aa)
Arch_1670FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR016156:IPR013027:IPR004099; KEGG: cdi:DIP1748 putative oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: C2CQM4 CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain. (538 aa)
Arch_1666Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake. (214 aa)
Arch_1665Histidine kinase; COGs: COG5002 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR009082:IPR005467:IPR 004358; KEGG: bcv:Bcav_0770 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C5BYS3 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (393 aa)
Arch_1664Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006:IPR016032:IPR001867; KEGG: mlu:Mlut_03750 PhoP-like protein; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C0W5A5 Response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (229 aa)
Arch_1635Hypothetical protein; KEGG: jde:Jden_1612 LPXTG-motif cell wall anchor domain protein; SPTR: C7R5I7 LPXTG-motif cell wall anchor domain protein; TIGRFAM: LPXTG-motif cell wall anchor domain. (428 aa)
Arch_1627COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR009082:IPR 005467:IPR004358; KEGG: kra:Krad_3621 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: D0WJT8 PhoR protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoaccept [...] (509 aa)
Arch_1626Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006:IPR001867; KEGG: xce:Xcel_2937 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D0WJT7 DNA-binding response regulator PhoP; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (248 aa)
Arch_1622Cold-shock DNA-binding domain protein; COGs: COG1278 Cold shock protein; InterPro IPR011129:IPR016027:IPR002059:IPR012340; KEGG: bcv:Bcav_0848 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: D0WJT4 Cold-shock domain protein; PFAM: 'Cold-shock' DNA-binding domain. (143 aa)
Arch_1618Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367:IPR008988:IPR007167:IPR011991; KEGG: jde:Jden_1989 iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; FeoA family protein; SMART: iron dependent repressor; SPTR: C7R0G3 Iron (Metal) dependent repressor, DtxR family; PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain. (225 aa)
Arch_1604Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR001789:IPR000792:IPR011006:IPR016032:IPR 011991; KEGG: rer:RER_47120 NarL family two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: C0ZN12 Putative NarL family two-component response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (201 aa)
Arch_1603COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: kse:Ksed_01000 signal transduction histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: C2BTB8 Two component system histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (359 aa)
Arch_1590Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR004341; KEGG: dda:Dd703_1406 transcriptional antiterminator, BglG; PFAM: PRD domain protein; CAT RNA-binding domain protein; SPTR: C2GFH3 Transcriptional antiterminator; PFAM: CAT RNA binding domain; PRD domain. (280 aa)
Arch_1585InterPro IPR000835:IPR011991; KEGG: bcv:Bcav_0980 transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: C1YV56 Transcriptional regulator, MarR family; PFAM: MarR family. (176 aa)
Arch_1581Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system. (68 aa)
Arch_1557Transcriptional regulator, ArsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845:IPR011991; KEGG: kse:Ksed_25700 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: C8NVC6 ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family. (129 aa)
Arch_1551Transcriptional regulator, ArsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845:IPR011991; KEGG: nml:Namu_2556 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: C8X7G0 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family. (100 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1168 aa)
greAGreA/GreB family elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (159 aa)
Arch_1488Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR010982; KEGG: sth:STH770 LacI family transcriptional repressor; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: C0W1U4 Putative uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family. (337 aa)
Arch_1483InterPro IPR005149:IPR011991; KEGG: cby:CLM_2307 transcriptional regulator, PadR family; PFAM: transcriptional regulator PadR family protein; SPTR: C1FQA7 Transcriptional regulator, PadR family; PFAM: Transcriptional regulator PadR-like family. (106 aa)
Arch_1478Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR010982; KEGG: sco:SCO5692 transcriptional regulator; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: C0W8S7 Regulatory protein LacI family protein; PFAM: Bacterial regulatory proteins, lacI family; family. (343 aa)
Arch_1459Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR004341; KEGG: bad:BAD_0367 transcription antiterminator LicT; PFAM: CAT RNA-binding domain protein; PRD domain protein; SPTR: B1S6B5 Putative uncharacterized protein; PFAM: CAT RNA binding domain; PRD domain. (281 aa)
Arch_1437GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR000795:IPR004161:IPR000640:IPR005225:IPR 006298:IPR009022:IPR009000; KEGG: jde:Jden_0793 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain protein; SPTR: D0WPN3 GTP-binding protein TypA/BipA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small [...] (641 aa)
Arch_1430COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR009061; KEGG: bcv:Bcav_1154 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; PRIAM: Adenylate cyclase; SPTR: D0WPL7 Putative adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain. (345 aa)
Arch_1429Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: bcv:Bcav_1155 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: A7B947 Putative uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (226 aa)
Arch_1428COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003661:IPR003594:IPR 009082:IPR004358; KEGG: bcv:Bcav_1156 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: D0WPL5 Putative two-component system histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (438 aa)
whiB-3Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (110 aa)
Arch_1419Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: mva:Mvan_1752 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D0WPH5 DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (224 aa)
Arch_1418COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003661:IPR003594:IPR 009082:IPR004358; KEGG: bcv:Bcav_1241 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: D0WPH4 Sensor histidine kinase MtrB; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (554 aa)
hpfRibosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (222 aa)
nusGNusG antitermination factor; Participates in transcription elongation, termination and antitermination. (288 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (233 aa)
Arch_1394KEGG: cdi:DIP2121 hypothetical protein; SPTR: D0WPQ4 PAS/PAC domain protein; TIGRFAM: PAS domain S-box. (442 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (706 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa)
whiB-2Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (98 aa)
Arch_1282Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR000792:IPR001789:IPR011991:IPR011006:IPR 016032; KEGG: jde:Jden_0656 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: C7R1A5 Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (222 aa)
Arch_1260KEGG: xce:Xcel_0979 hypothetical protein; SPTR: C1RFG8 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3117). (59 aa)
Arch_1235Multiple antibiotic resistance (MarC)-related protein; COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: cai:Caci_8100 multiple antibiotic resistance (MarC)-related protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: D0YNY9 Membrane protein; PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427. (207 aa)
Arch_1224KEGG: xce:Xcel_1029 TadE family protein; SPTR: A1R814 Putative TadE-like family protein. (121 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (376 aa)
Arch_1197Addiction module antitoxin, RelB/DinJ family; InterPro IPR007337; KEGG: blt:Balat_1584 hypothetical protein; PFAM: RelB antitoxin; SPTR: C6AG15 Putative uncharacterized protein; TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family. (87 aa)
Arch_1191Hypothetical protein; KEGG: lca:LSEI_1243 XRE family transcriptional regulator; SPTR: C0CY08 Putative uncharacterized protein. (142 aa)
Arch_1189Transcriptional regulator, XRE family; COGs: COG1476 transcriptional regulator protein; InterPro IPR010982:IPR001387; KEGG: mlu:Mlut_02550 predicted transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: D0YR80 Transcriptional regulator; PFAM: Helix-turn-helix. (65 aa)
Arch_1187Transcriptional regulator, MerR family; COGs: COG0789 transcriptional regulator protein; InterPro IPR009061:IPR000551:IPR015358:IPR012925; KEGG: cur:cur_0383 MerR family transcriptional regulator; PFAM: TipAS antibiotic-recognition domain protein; regulatory protein MerR; Transcription regulator MerR DNA binding; SMART: regulatory protein MerR; SPTR: B1VF04 Putative transcriptional regulator (MerR family); PFAM: MerR family regulatory protein; MerR, DNA binding; TipAS antibiotic-recognition domain. (262 aa)
Arch_1180InterPro IPR009057:IPR001647:IPR012287; KEGG: cjk:jk0810 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: C5VD50 Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family. (223 aa)
Arch_1149Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524:IPR011991; KEGG: apr:Apre_0169 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: C0W8Y6 GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family. (126 aa)
Arch_1131Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003594:IPR009082:IPR005467:IPR003661:IPR 004358; KEGG: xce:Xcel_2991 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: D1BZA0 Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (266 aa)
Arch_1130Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR000463:IPR001867; KEGG: xce:Xcel_2992 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D0YTJ0 Transcriptional regulatory protein ResD; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (227 aa)
Arch_1095Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: xce:Xcel_2358 transcriptional regulator, IclR family; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: D1BVQ5 Transcriptional regulator, IclR family; manually curated; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator. (243 aa)
Arch_1078Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR011006:IPR000792:IPR001789:IPR011991; KEGG: jde:Jden_1659 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WNC4 DNA-binding response regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (207 aa)
Arch_1077COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR003018:IPR011712; KEGG: bcv:Bcav_1613 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: GAF domain protein; ATP-binding region ATPase domain protein; SPTR: D0WNC3 Putative two-component sensor; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain. (544 aa)
Arch_1076ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; COGs: COG4987 ABC-type transport system involved in cytochrome bd biosynthesis fused ATPase and permease components; InterProIPR011527:IPR014223:IPR003439:IPR017940:IPR 017871:IPR003593; KEGG: bcv:Bcav_1614 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: C0W2T3 ABC superfamily ATP binding cassette transporter, ABC protein CydC; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family [...] (586 aa)
Arch_1067Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR012336:IPR005746:IPR017936:IPR017937:IPR 012335:IPR013766:IPR006662; KEGG: cur:cur_1977 thioredoxin; PFAM: Thioredoxin domain; SPTR: B1VIY8 Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. (121 aa)
rsfSIojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (155 aa)
Arch_1056KEGG: ere:EUBREC_3502 hypothetical protein; SPTR: C0FM79 Putative uncharacterized protein. (196 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (619 aa)
hrcAHeat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (342 aa)
infCTranslation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (202 aa)
argRArginine repressor, ArgR; Regulates arginine biosynthesis genes. (169 aa)
Arch_0938COGs: COG2345 transcriptional regulator protein; InterPro IPR001845; KEGG: jde:Jden_1139 putative transcriptional regulator; PFAM: regulatory protein ArsR; SPTR: D0WMJ3 Putative DNA-binding transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family. (243 aa)
Arch_0929COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR017871:IPR003593:IPR003439; KEGG: bcv:Bcav_2326 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: D0WMK2 ABC transporter, ATP-binding protein; PFAM: ABC transporter. (537 aa)
Arch_0922Transcriptional regulator, XRE family; InterPro IPR010982:IPR001387; KEGG: xce:Xcel_0778 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: D0WML6 DNA-binding protein; PFAM: Helix-turn-helix. (102 aa)
Arch_0898Response regulator receiver and ANTAR domain protein; COGs: COG3707 Response regulator with putative antiterminator output domain; InterProIPR011006:IPR001789:IPR008327:IPR005561:IPR 011991; KEGG: bfa:Bfae_14950 response regulator with putative antiterminator output domain; PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; SPTR: D0WMQ2 Two-component system response regulator; PFAM: Response regulator receiver domain; ANTAR domain. (209 aa)
Arch_0887Conserved hypothetical protein; Displays ATPase and GTPase activities. (311 aa)
Arch_0871COGs: COG1716 FOG: FHA domain; InterPro IPR008984:IPR000253; KEGG: bcv:Bcav_2102 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: D0WMV9 GarA protein; PFAM: FHA domain. (150 aa)
Arch_0870InterPro IPR009061:IPR000551; KEGG: bcv:Bcav_2101 transcriptional regulator, MerR family; SMART: regulatory protein MerR; SPTR: D0WMW0 Regulatory protein, MerR family. (250 aa)
Arch_0869InterPro IPR009061:IPR000551; KEGG: bcv:Bcav_2099 transcriptional regulator, MerR family; SMART: regulatory protein MerR; SPTR: C5C6E6 Transcriptional regulator, MerR family. (187 aa)
rbpAHypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. (117 aa)
Arch_0865Hypothetical protein; KEGG: tcu:Tcur_2317 transcriptional regulator-like protein; SPTR: D0WMW9 Putative uncharacterized protein. (301 aa)
Arch_0864COGs: COG2378 transcriptional regulator protein; KEGG: kse:Ksed_13990 predicted transcriptional regulator; SPTR: D0WMX0 Putative uncharacterized protein. (301 aa)
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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