(29 nodes) RNA Pol II CTD phosphorylation and interaction with CE network (Gaeumannomyces tritici)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GGTG_01635	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1765 aa)
	GGTG_00907	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1042 aa)
	GGTG_00871	mRNA cap guanine-N7 methyltransferase. (486 aa)
	GGTG_00955	CDK-activating kinase assembly factor MAT1. (354 aa)
	GGTG_01102	Dual specificity phosphatase catalytic domain-containing protein. (703 aa)
	GGTG_01448	Uncharacterized protein. (170 aa)
	GGTG_12744	RPOL9 domain-containing protein. (277 aa)
	GGTG_11298	DNA-directed RNA polymerase II subunit RPB3. (340 aa)
	GGTG_11279	RNA polymerase II transcription factor B subunit 1. (661 aa)
	GGTG_11190	VWFA domain-containing protein. (540 aa)
	GGTG_10356	DNA repair helicase rad15. (791 aa)
	GGTG_10304	Uncharacterized protein. (561 aa)
	GGTG_10089	DNA-directed RNA polymerase N/8 kDa subunit. (77 aa)
	GGTG_09739	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1278 aa)
	GGTG_09646	RPOL4c domain-containing protein. (143 aa)
	GGTG_09463	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (412 aa)
	GGTG_09429	DNA-directed RNA polymerase I. (155 aa)
	GGTG_08820	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (155 aa)
	GGTG_08799	Uncharacterized protein. (737 aa)
	GGTG_07057	Uncharacterized protein. (78 aa)
	GGTG_06562	Cyclin_C_2 domain-containing protein. (442 aa)
	GGTG_06227	RNA_pol_L_2 domain-containing protein. (130 aa)
	GGTG_04448	RNA polymerase II transcription factor B subunit 4. (382 aa)
	GGTG_04121	DNA-directed RNA polymerase I. (233 aa)
	GGTG_03847	Uncharacterized protein. (85 aa)
	GGTG_03791	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (496 aa)
	GGTG_02735	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (426 aa)
	GGTG_01966	Uncharacterized protein. (379 aa)
	GGTG_01691	DNA repair helicase RAD25. (818 aa)

Your Current Organism:

Gaeumannomyces tritici

NCBI taxonomy Id: 644352
Other names: G. tritici R3-111a-1, Gaeumannomyces graminis var. tritici R3-111a-1, Gaeumannomyces tritici R3-111a-1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GGTG_00871	GGTG_00907	J3NHY5	J3NI23	mRNA cap guanine-N7 methyltransferase.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.992
GGTG_00871	GGTG_01102	J3NHY5	J3NIM4	mRNA cap guanine-N7 methyltransferase.	Dual specificity phosphatase catalytic domain-containing protein.	0.821
GGTG_00871	GGTG_01448	J3NHY5	J3NJL8	mRNA cap guanine-N7 methyltransferase.	Uncharacterized protein.	0.717
GGTG_00871	GGTG_01635	J3NHY5	J3NK53	mRNA cap guanine-N7 methyltransferase.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.791
GGTG_00871	GGTG_01966	J3NHY5	J3NL25	mRNA cap guanine-N7 methyltransferase.	Uncharacterized protein.	0.682
GGTG_00871	GGTG_02735	J3NHY5	J3NN77	mRNA cap guanine-N7 methyltransferase.	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily.	0.732
GGTG_00871	GGTG_04121	J3NHY5	J3NS76	mRNA cap guanine-N7 methyltransferase.	DNA-directed RNA polymerase I.	0.736
GGTG_00871	GGTG_04448	J3NHY5	J3NT50	mRNA cap guanine-N7 methyltransferase.	RNA polymerase II transcription factor B subunit 4.	0.821
GGTG_00871	GGTG_06562	J3NHY5	J3NZ62	mRNA cap guanine-N7 methyltransferase.	Cyclin_C_2 domain-containing protein.	0.667
GGTG_00871	GGTG_08799	J3NHY5	J3P5K9	mRNA cap guanine-N7 methyltransferase.	Uncharacterized protein.	0.656
GGTG_00871	GGTG_08820	J3NHY5	J3P5N0	mRNA cap guanine-N7 methyltransferase.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.741
GGTG_00871	GGTG_09463	J3NHY5	J3P7H2	mRNA cap guanine-N7 methyltransferase.	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family.	0.858
GGTG_00871	GGTG_09739	J3NHY5	J3P8A5	mRNA cap guanine-N7 methyltransferase.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.828
GGTG_00871	GGTG_10304	J3NHY5	J3P9Y0	mRNA cap guanine-N7 methyltransferase.	Uncharacterized protein.	0.689
GGTG_00871	GGTG_11298	J3NHY5	J3PCT0	mRNA cap guanine-N7 methyltransferase.	DNA-directed RNA polymerase II subunit RPB3.	0.825
GGTG_00871	GGTG_12744	J3NHY5	J3PGW4	mRNA cap guanine-N7 methyltransferase.	RPOL9 domain-containing protein.	0.721
GGTG_00907	GGTG_00871	J3NI23	J3NHY5	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	mRNA cap guanine-N7 methyltransferase.	0.992
GGTG_00907	GGTG_00955	J3NI23	J3NI72	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	CDK-activating kinase assembly factor MAT1.	0.727
GGTG_00907	GGTG_01102	J3NI23	J3NIM4	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Dual specificity phosphatase catalytic domain-containing protein.	0.904
GGTG_00907	GGTG_01448	J3NI23	J3NJL8	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.996