(42 nodes) Valine, leucine and isoleucine biosynthesis network (Gaeumannomyces tritici)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GGTG_08265	2-isopropylmalate synthase. (634 aa)
	GGTG_02474	HET domain-containing protein. (135 aa)
	GGTG_14031	Uncharacterized protein. (346 aa)
	GGTG_13921	HET domain-containing protein. (837 aa)
	GGTG_13406	HET domain-containing protein. (734 aa)
	GGTG_13289	Uncharacterized protein. (492 aa)
	GGTG_13222	HET domain-containing protein. (753 aa)
	GGTG_13070	HET domain-containing protein. (843 aa)
	GGTG_13015	HET domain-containing protein. (751 aa)
	GGTG_11796	HET domain-containing protein. (709 aa)
	GGTG_11560	HET domain-containing protein. (649 aa)
	GGTG_11003	Branched-chain-amino-acid aminotransferase 1. (392 aa)
	GGTG_10911	HET domain-containing protein. (707 aa)
	GGTG_10834	HET domain-containing protein. (814 aa)
	GGTG_10453	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (381 aa)
	GGTG_10060	HET domain-containing protein. (902 aa)
	GGTG_09837	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (366 aa)
	GGTG_09304	HET domain-containing protein. (637 aa)
	GGTG_08844	Uncharacterized protein. (207 aa)
	GGTG_08700	HET domain-containing protein. (243 aa)
	GGTG_07043	HET domain-containing protein. (519 aa)
	GGTG_06866	Uncharacterized protein. (417 aa)
	GGTG_06707	Uncharacterized protein. (620 aa)
	GGTG_06700	HET domain-containing protein. (1190 aa)
	GGTG_06635	HET domain-containing protein. (626 aa)
	GGTG_06454	HET domain-containing protein. (736 aa)
	GGTG_06245	L-serine dehydratase. (355 aa)
	GGTG_06016	Dihydroxy-acid dehydratase. (602 aa)
	GGTG_05988	Acetolactate synthase. (699 aa)
	GGTG_05882	HET domain-containing protein. (877 aa)
	GGTG_04383	Acetolactate synthase; Belongs to the TPP enzyme family. (562 aa)
	GGTG_04263	Acetolactate synthase small subunit. (312 aa)
	GGTG_04074	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (778 aa)
	GGTG_03209	Dihydroxy-acid dehydratase. (636 aa)
	GGTG_02940	Uncharacterized protein. (200 aa)
	GGTG_02560	C6 zinc finger domain-containing protein. (586 aa)
	GGTG_02394	Uncharacterized protein. (448 aa)
	GGTG_02244	HET domain-containing protein. (733 aa)
	GGTG_00888	Threonine dehydratase. (608 aa)
	GGTG_00684	Branched-chain-amino-acid aminotransferase. (426 aa)
	GGTG_00616	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (405 aa)
	GGTG_00026	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (401 aa)

Your Current Organism:

Gaeumannomyces tritici

NCBI taxonomy Id: 644352
Other names: G. tritici R3-111a-1, Gaeumannomyces graminis var. tritici R3-111a-1, Gaeumannomyces tritici R3-111a-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GGTG_00026	GGTG_00616	J3NFI0	J3NH78	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.620
GGTG_00026	GGTG_00888	J3NFI0	J3NI03	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	Threonine dehydratase.	0.594
GGTG_00026	GGTG_03209	J3NFI0	J3NPK1	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	Dihydroxy-acid dehydratase.	0.914
GGTG_00026	GGTG_04074	J3NFI0	J3NS27	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.698
GGTG_00026	GGTG_04263	J3NFI0	J3NSL2	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	Acetolactate synthase small subunit.	0.953
GGTG_00026	GGTG_04383	J3NFI0	J3NSY4	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	Acetolactate synthase; Belongs to the TPP enzyme family.	0.853
GGTG_00026	GGTG_05988	J3NFI0	J3NXI2	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	Acetolactate synthase.	0.969
GGTG_00026	GGTG_06016	J3NFI0	J3NXL0	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	Dihydroxy-acid dehydratase.	0.968
GGTG_00026	GGTG_06707	J3NFI0	J3NZK9	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	Uncharacterized protein.	0.968
GGTG_00026	GGTG_08265	J3NFI0	J3P428	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	2-isopropylmalate synthase.	0.499
GGTG_00616	GGTG_00026	J3NH78	J3NFI0	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	0.620
GGTG_00616	GGTG_00684	J3NH78	J3NHE7	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Branched-chain-amino-acid aminotransferase.	0.904
GGTG_00616	GGTG_00888	J3NH78	J3NI03	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Threonine dehydratase.	0.873
GGTG_00616	GGTG_03209	J3NH78	J3NPK1	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Dihydroxy-acid dehydratase.	0.966
GGTG_00616	GGTG_04074	J3NH78	J3NS27	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.555
GGTG_00616	GGTG_04263	J3NH78	J3NSL2	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Acetolactate synthase small subunit.	0.821
GGTG_00616	GGTG_04383	J3NH78	J3NSY4	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Acetolactate synthase; Belongs to the TPP enzyme family.	0.837
GGTG_00616	GGTG_05988	J3NH78	J3NXI2	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Acetolactate synthase.	0.837
GGTG_00616	GGTG_06016	J3NH78	J3NXL0	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Dihydroxy-acid dehydratase.	0.972
GGTG_00616	GGTG_06245	J3NH78	J3NY92	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	L-serine dehydratase.	0.847