(56 nodes) Propanoate metabolism network (Gaeumannomyces tritici)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GGTG_08582	Uncharacterized protein. (1594 aa)
	GGTG_08586	Extracellular metalloprotease. (436 aa)
	GGTG_08594	Uncharacterized protein. (490 aa)
	GGTG_08881	Epimerase domain-containing protein. (334 aa)
	GGTG_00678	Uncharacterized protein. (318 aa)
	GGTG_02030	Epimerase domain-containing protein. (348 aa)
	GGTG_01942	Uncharacterized protein. (297 aa)
	GGTG_01910	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (515 aa)
	GGTG_01563	Methylmalonate-semialdehyde dehydrogenase. (585 aa)
	GGTG_01316	Probable acetate kinase. (468 aa)
	GGTG_00963	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	GGTG_00865	2-oxoisovalerate dehydrogenase subunit beta. (411 aa)
	GGTG_00794	Propionate-CoA ligase. (703 aa)
	GGTG_09969	SET domain-containing protein. (377 aa)
	GGTG_10277	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (542 aa)
	GGTG_10723	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (444 aa)
	GGTG_11046	Uncharacterized protein. (483 aa)
	GGTG_11305	Acetyl-coenzyme A synthetase. (668 aa)
	GGTG_09933	SET domain-containing protein 8. (403 aa)
	GGTG_09772	2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
	GGTG_09520	S-(Hydroxymethyl)glutathione dehydrogenase. (418 aa)
	GGTG_09122	ADH_N domain-containing protein. (416 aa)
	GGTG_09043	Uncharacterized protein. (725 aa)
	GGTG_09025	Carnitinyl-CoA dehydratase. (287 aa)
	GGTG_11497	Uncharacterized protein. (472 aa)
	GGTG_11582	SET domain-containing protein. (305 aa)
	GGTG_11865	S-(Hydroxymethyl)glutathione dehydrogenase. (460 aa)
	GGTG_12033	2-methylcitrate dehydratase. (574 aa)
	GGTG_12279	Uncharacterized protein. (432 aa)
	GGTG_12313	Leucoanthocyanidin reductase. (360 aa)
	GGTG_12376	Uncharacterized protein. (565 aa)
	GGTG_12537	Uncharacterized protein. (394 aa)
	GGTG_13728	Epimerase domain-containing protein. (346 aa)
	GGTG_13957	Acetyl-CoA carboxylase. (2333 aa)
	GGTG_14226	ADH_N domain-containing protein. (85 aa)
	GGTG_02739	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
	GGTG_03049	Uncharacterized protein. (484 aa)
	GGTG_03227	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (468 aa)
	GGTG_03837	Uncharacterized protein. (650 aa)
	GGTG_03873	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	GGTG_03967	Uncharacterized protein. (328 aa)
	GGTG_04054	3-hydroxyisobutyrate dehydrogenase. (349 aa)
	GGTG_04388	NADPH-dependent methylglyoxal reductase GRE2. (351 aa)
	GGTG_04989	Uncharacterized protein. (293 aa)
	GGTG_05225	Dihydrolipoyl dehydrogenase. (508 aa)
	GGTG_05290	Epimerase domain-containing protein. (339 aa)
	GGTG_05936	Epimerase domain-containing protein. (387 aa)
	GGTG_06541	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (332 aa)
	GGTG_07351	Uncharacterized protein. (405 aa)
	GGTG_07407	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (471 aa)
	GGTG_07512	Enoyl-CoA hydratase/isomerase. (278 aa)
	GGTG_07590	AB hydrolase-1 domain-containing protein. (537 aa)
	GGTG_07631	Uncharacterized protein. (318 aa)
	GGTG_07827	Peroxisomal hydratase-dehydrogenase-epimerase. (896 aa)
	GGTG_07927	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (499 aa)
	GGTG_08398	Uncharacterized protein. (2016 aa)

Your Current Organism:

Gaeumannomyces tritici

NCBI taxonomy Id: 644352
Other names: G. tritici R3-111a-1, Gaeumannomyces graminis var. tritici R3-111a-1, Gaeumannomyces tritici R3-111a-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GGTG_00678	GGTG_00794	J3NHE1	J3NHQ7	Uncharacterized protein.	Propionate-CoA ligase.	0.466
GGTG_00678	GGTG_00865	J3NHE1	J3NHX9	Uncharacterized protein.	2-oxoisovalerate dehydrogenase subunit beta.	0.994
GGTG_00678	GGTG_01942	J3NHE1	J3NL01	Uncharacterized protein.	Uncharacterized protein.	0.486
GGTG_00678	GGTG_05225	J3NHE1	J3NVB2	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.886
GGTG_00678	GGTG_06541	J3NHE1	J3NZ41	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.484
GGTG_00678	GGTG_07827	J3NHE1	J3P2T5	Uncharacterized protein.	Peroxisomal hydratase-dehydrogenase-epimerase.	0.475
GGTG_00678	GGTG_09772	J3NHE1	J3P8D8	Uncharacterized protein.	2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.481
GGTG_00678	GGTG_10277	J3NHE1	J3P9V3	Uncharacterized protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.964
GGTG_00678	GGTG_10723	J3NHE1	J3PB50	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.417
GGTG_00678	GGTG_11046	J3NHE1	J3PC23	Uncharacterized protein.	Uncharacterized protein.	0.886
GGTG_00678	GGTG_11305	J3NHE1	J3PCT7	Uncharacterized protein.	Acetyl-coenzyme A synthetase.	0.466
GGTG_00678	GGTG_12279	J3NHE1	J3PFK4	Uncharacterized protein.	Uncharacterized protein.	0.417
GGTG_00678	GGTG_13957	J3NHE1	J3PKA7	Uncharacterized protein.	Acetyl-CoA carboxylase.	0.736
GGTG_00794	GGTG_00678	J3NHQ7	J3NHE1	Propionate-CoA ligase.	Uncharacterized protein.	0.466
GGTG_00794	GGTG_00865	J3NHQ7	J3NHX9	Propionate-CoA ligase.	2-oxoisovalerate dehydrogenase subunit beta.	0.472
GGTG_00794	GGTG_00963	J3NHQ7	J3NI80	Propionate-CoA ligase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.817
GGTG_00794	GGTG_01316	J3NHQ7	J3NJ82	Propionate-CoA ligase.	Probable acetate kinase.	0.900
GGTG_00794	GGTG_01563	J3NHQ7	J3NJY1	Propionate-CoA ligase.	Methylmalonate-semialdehyde dehydrogenase.	0.917
GGTG_00794	GGTG_01910	J3NHQ7	J3NKW9	Propionate-CoA ligase.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.774
GGTG_00794	GGTG_01942	J3NHQ7	J3NL01	Propionate-CoA ligase.	Uncharacterized protein.	0.804