(31 nodes) Butanoate metabolism network (Gaeumannomyces tritici)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GGTG_04263	Acetolactate synthase small subunit. (312 aa)
	GGTG_10919	Pyruvate carboxyltransferase domain-containing protein. (398 aa)
	GGTG_11109	Uncharacterized protein. (388 aa)
	GGTG_11134	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (532 aa)
	GGTG_11706	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (639 aa)
	GGTG_11930	Uncharacterized protein. (373 aa)
	GGTG_10454	Aldedh domain-containing protein. (503 aa)
	GGTG_00963	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	GGTG_01008	Acetoacetate-CoA ligase. (692 aa)
	GGTG_01910	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (515 aa)
	GGTG_02519	Integral membrane protein. (378 aa)
	GGTG_02580	NmrA domain-containing protein. (309 aa)
	GGTG_02606	3-hydroxybutyryl-CoA dehydrogenase. (320 aa)
	GGTG_02739	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (434 aa)
	GGTG_02997	DAO domain-containing protein. (429 aa)
	GGTG_03226	Succinate-semialdehyde dehydrogenase. (489 aa)
	GGTG_03227	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (468 aa)
	GGTG_03325	Potassium-activated aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa)
	GGTG_03873	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	GGTG_03971	Succinate-semialdehyde dehydrogenase. (539 aa)
	GGTG_04383	Acetolactate synthase; Belongs to the TPP enzyme family. (562 aa)
	GGTG_04384	Alpha-acetolactate decarboxylase. (253 aa)
	GGTG_05579	Uncharacterized protein. (274 aa)
	GGTG_05745	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (530 aa)
	GGTG_05988	Acetolactate synthase. (699 aa)
	GGTG_06898	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (475 aa)
	GGTG_07512	Enoyl-CoA hydratase/isomerase. (278 aa)
	GGTG_07590	AB hydrolase-1 domain-containing protein. (537 aa)
	GGTG_09772	2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
	GGTG_12550	AMP-binding domain-containing protein. (721 aa)
	GGTG_10675	Cysteine sulfinic acid decarboxylase. (509 aa)

Your Current Organism:

Gaeumannomyces tritici

NCBI taxonomy Id: 644352
Other names: G. tritici R3-111a-1, Gaeumannomyces graminis var. tritici R3-111a-1, Gaeumannomyces tritici R3-111a-1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GGTG_00963	GGTG_01008	J3NI80	J3NIC6	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetate-CoA ligase.	0.940
GGTG_00963	GGTG_02519	J3NI80	J3NML3	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Integral membrane protein.	0.870
GGTG_00963	GGTG_02606	J3NI80	J3NMU7	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyryl-CoA dehydrogenase.	0.981
GGTG_00963	GGTG_02739	J3NI80	J3NN81	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.903
GGTG_00963	GGTG_03325	J3NI80	J3NPW8	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Potassium-activated aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.414
GGTG_00963	GGTG_03873	J3NI80	J3NRG9	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.885
GGTG_00963	GGTG_05579	J3NI80	J3NWB5	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.870
GGTG_00963	GGTG_05745	J3NI80	J3NWT4	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.946
GGTG_00963	GGTG_06898	J3NI80	J3P051	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.995
GGTG_00963	GGTG_07512	J3NI80	J3P1W4	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase/isomerase.	0.867
GGTG_00963	GGTG_07590	J3NI80	J3P242	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	AB hydrolase-1 domain-containing protein.	0.637
GGTG_00963	GGTG_10919	J3NI80	J3PBP8	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Pyruvate carboxyltransferase domain-containing protein.	0.939
GGTG_00963	GGTG_11930	J3NI80	J3PEJ9	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.870
GGTG_00963	GGTG_12550	J3NI80	J3PGC5	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	AMP-binding domain-containing protein.	0.940
GGTG_01008	GGTG_00963	J3NIC6	J3NI80	Acetoacetate-CoA ligase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.940
GGTG_01008	GGTG_01910	J3NIC6	J3NKW9	Acetoacetate-CoA ligase.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.421
GGTG_01008	GGTG_02519	J3NIC6	J3NML3	Acetoacetate-CoA ligase.	Integral membrane protein.	0.552
GGTG_01008	GGTG_02606	J3NIC6	J3NMU7	Acetoacetate-CoA ligase.	3-hydroxybutyryl-CoA dehydrogenase.	0.933
GGTG_01008	GGTG_02739	J3NIC6	J3NN81	Acetoacetate-CoA ligase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.940
GGTG_01008	GGTG_03226	J3NIC6	J3NPL8	Acetoacetate-CoA ligase.	Succinate-semialdehyde dehydrogenase.	0.554