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| mutM | Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (295 aa) | ||||
| EGD55593.1 | DNA-(apurinic or apyrimidinic site) lyase; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (231 aa) | ||||
| EGD54645.1 | COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (294 aa) | ||||